1.Plate fixation and small splint for intraarticular fracture of distal radius:comparison of curative effects
Chinese Journal of Tissue Engineering Research 2014;(4):631-636
BACKGROUND:At present, there are many clinical trials concerning plate fixation and smal splint for distal radius fracture, but there is lack of systemic evaluation.
OBJECTIVE:To evaluate the curative effect of the plate fixation and smal splint in the treatment of intraarticular fractures of the distal radius.
METHODS:We retrieved the Chinese biomedical database (1979-2008), China National Knowledge Infrastructure (1979-2008), VIP database (1989-2008) and Wanfang Digital Periodical Group (1998-2008). Of them, China National Knowledge Infrastructure contained Chinese periodical databases, important meeting ful-text databases, and Master-Doctor thesis database. Foreign databases included PubMed (1966-2008), EMbase (1980-2008) and the Cochrane Library (2008, 4th). The ful text that could access was supplemented by manual search back issues of Traditional Chinese Medicine, Tianjin University Library repository. Clinical randomized control ed trials addressing plate fixation with smal splint in the treatment of intraarticular distal radius fractures were col ected. The data were extracted independent by two evaluators and methodological quality assessment was performed. According to the search strategy and data col ection methods, 363 English articles and 488 Chinese articles were found, including 401 periodical literatures, 79 conference proceedings, and 8 theses. After reading title, abstract, ful text, 12 articles met the inclusion criteria. Meta analysis was conducted with RevMan 5.0.20 software provided by the Cochrane Col aboration Network.
RESULTS AND CONCLUSION:The evaluation of this system involves locking compression plate, normal internal fixation with plate, smal splints and plaster external fixation methods. Meta analysis of the results shows that the curative effects of locking compression plate in the treatment of intraarticular fracture of distal radius were better than that of common plate, smal splint or gypsum. Moreover, there were few complications. There is no significant difference in the effects between common plate fixation in treatment of intraarticular fracture of distal radius and the fixation with smal splint or gypsum.
2.PURIFICATION AND PHYSICOCHEMICAL CHARACTERIZATION OF ALLERGEN I from Dermatophagoides farinae
Chinese Journal of Parasitology and Parasitic Diseases 1987;0(03):-
Dermatophagoid.es farinae allergen Ⅰ (Der f Ⅰ ) has been extracted and purified from spent culture medium of Dermatophagoid.es farinae by affinity chromatography coupled with anti-Der f Ⅰ McAb for the first time in China. Furthermore,its physicochemical properties were analysed. By SDS-PAGE,.Der f Ⅰ was estimated to have a molecular weight of 24 kDa and appeared as only one protein band. By isoelectric focusing ,it was revealed to have pIs of 4. 8 - 7. 5 with six protein bands,suggesting that Der f Ⅰ is heterogeneous with complicated composition.
3.Minimal incision osteotomy for tailor's bunion
Jianmin WEN ; Weidong SUN ; Si CHEN
Orthopedic Journal of China 2006;0(23):-
[Objective] To retrospectively analyze the treatment of tailor's bunion with minimal incision osteotomy,and to investigate the indications and effects of this procedure.[Method]Thirty-seven patients(69 feet)underwent the procedure from July 2002 to August 2007.The axial and lateral films of all feet with loading were taken before and after operation.AOFAS were recorded and analyzed preoperatively and postoperatively.[Result]The forth intermetatarsal angle was 14.36??7.32? before operation and 9.36??2.92?after operation.The unguis aduncus angle of digitus quintus pedis was 20.44??7.36? before operation and 4.36??1.35?after operation.The forth reforming intermetatarsal angle was 10.36??.2.81? before operation and 7.83??2.37?after operation.The exstrophy angle of the fifth metatarsal was 5.46??1.70? before operation and 2.13??0.38?after operation.The score of AOFAS was 45.7?5.6 before operation and 85.3?5.1 after operation.[Conclusion]The treatment of tailor's bunion with minimal incision osteotomy is easy to operate and its therapeutic effect is convincing.
4.The Value of Diffusion Weighted Imaging Used in Breast Disease
Caiqiao ZHU ; Yao CHEN ; Jianmin WEN
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To evaluate the value of diffusion weighted imaging(DWI)in breast disease.[Methods]7 cases suspected by molybdenum target and clinic were detected by MRI.we calculated ADC through two different b,also make time-signal plot.Then we compared the diagnostic conclusion to the normal MRI conclusion acquired with histopathological demonstration.[Results]3 cases were malignant,2 cases were benign and 2 cases were normal.The diagnostic coincidence rate of DWI and normal MRI was 100%.[Conclusion]DWI is a rapid and feasible method in detecting breast lesions.ADC is an effective parameter in discriminating malignant and benign breast lesions.
5.Investigation and Analysis of Usage of Chinese Patent Medicine of Western Medicine ;Doctors in General Hospitals
Bei WANG ; Jinxin LI ; Jianmin WEN
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(9):120-125
Objective To know the usage of Chinese patent medicine of western medicine doctors in general hospitals. Methods By means of informal discussion with experts, present situation was known; By means of screening questions in questionnaire, nationwide investigation was conducted by this questionnaire about Chinese patent medicine and the results were examined by statistical analysis. Results That the abuse of Chinese patent medicine by western medical doctors was quite common. The overall quality of their prescriptions was not good. Most of the doctors have never received specialized continuing education of traditional Chinese medicine, only having preliminary knowledge or nothing on syndrome differentiation and treatment of traditional Chinese medicine. Conclusion The management department should take following measures: further enhance continuing education of TCM;formulate related policies;improve present situation.
6.Biomechanical quantitative study in hallux valgus deformity associated with the second metatarsalgia
Jianmin WEN ; Haiwei HU ; Yongsheng SUN
Chinese Journal of Orthopaedics 2000;0(02):-
Objective To study the relation between the pressure in forefoot and the second metatarsalgia in hallux valgus deformity, finally to quantitatively analyze the pressure under the second metatarsal head which is a dangerous factor leading to second metatarsalgia. Methods Three groups volunteered for this study by a self-devised foot pressure measurement system: fifty-eight normal subjects (116 feet) without pain and deformity in foot, thirty-two patients (45 feet) with hallux valgus and pain only under the second metatarsal head, fifty-six patients (102 feet) with hallux valgus without symptoms of metatarsalgia. The percentage of pressure to weight was the criteria for data analysis. First the pressures under second metatarsal head among three groups were compared with each other. Secondly we used case-control study to identify whether it was high pressure that was likely to result in metatarsalgia. Finally we compared the pressure interval under second metatarsal head among three groups to define the pressure interval which might be a dangerous factor to second metatarsalgia. Results 1)The pressure beneath the second meatatarsal head in patients with metatarsalgia was the highest in the three groups (P
7.Clinical research of dependability between heredity and hallux valgus
Jianmin WEN ; Zhao LIANG ; Yun TONG
Orthopedic Journal of China 2006;0(07):-
[Objective]To explore the dependability between heredity and hallux valgus.[Method]A total(1 491) cases of family heredity of hallux valgus patients were investigated,the ages of these patients,ages of onset,ages of aggravation,hallux valgus angles were analyzed statistically.[Result]Conclusive family medical history exists in 69.48% of the(1 491) hallux valgus patients.There was distinguished difference between the patients with family history and those without heredity background on visiting ages,ages of onset,ages of aggravation;but no any difference between these two groups of patients on hallux valgus angles.[Conclusion]Heredity factor is the main cause of hallux valgus.It can influence only the onset of hallux valgus,but not the severe degree of latter.The patients with family history are earlier than those without heredity background about visiting ages,ages of onset,ages of aggravation.
8.Study on the construction of policy system for the application of appropriate health technologies in rural areas
Jianmin JIANG ; Wei ZHU ; Zhijun XIA ; Jie SHEN ; Xin WEN
Chinese Journal of Medical Science Research Management 2012;25(3):175-178
To enhance the capacity for extending and applying appropriate health technologies in rural areas in China,this paper proposes a supportive policy system that incoperates macro,average and microlevels. Thepolicysystemfocusesonorientation, incentives, regulationsand standardization,and its objectives and measures of each level are described.The policy system will contribute to the sustainable development rural health work.
9.Retrospective analysis of appropriate health technology policy in Zhejiang Province from 1991 to 2012
Yijia MA ; Wei ZHU ; Zhijun XIA ; Xin WEN ; Jianmin JIANG
Chinese Journal of Medical Science Research Management 2013;(2):102-103,114
This paper reviews the development of appropriate health technology policy from 1992 to 2012 in Zhejiang province.The evolvement of recent twenty years is classified into several stages and each is analysed and evaluated.This study provides reference for the establishment of appropriate health technology policy and the transformation of science and technology policy across the country.
10.Preliminary application of Solitaire AB in the thrombectomy of acute arterial occlusion of distal anterior circulation
Yibin FANG ; Wanling WEN ; Yongwei ZHANG ; Qinghai HUANG ; Jianmin LIU
Chinese Journal of Cerebrovascular Diseases 2015;(8):430-434
Objective To investigate the effect of mechanical thrombectomy device Solitaire AB for the treatment of distal occlusion of the intracranial artery caused acute anterior circulation ischemic stroke. Methods The clinical data of 9 patients with arterial occlusion of distal anterior circulation treated by using the Solitaire AB thrombectomy device were analyzed retrospectively. Seven of them had M2 middle cerebral artery occlusion and 2 had A3 occlusion. Their clinical features,imaging data,treatment,and the results of 3-month clinical follow-up were analyzed. The effectiveness of treatment was evaluated through the recanalization rate after stent thrombectomy,the National Institutes of Health Stroke Scale (NIHSS)scores before and after treatment,the modified Rankin scale (mRS)scores,and the 3-month clinical follow-up results. The surgery-related complications and mortality of patients were used to evaluate the safety of the treatment. Results (1 )Of the 9 intracranial arterial occlusions,8 were recanalized successfully. The modified thrombolysis in cerebral infarction (mTICI)was 2b or grade 3. (2)The NIHSS score median 9. 5 (3. 0,15. 5)at discharge dropped significantly compared with 19. 0 (16. 0,22. 0)before procedure. (Z=2. 703,P=0. 007). No permanent complications related to operation occurred. Four of the recanalized patients had good prognosis (mRS 0-1)and 4 had disability (mRS 3-4 ). The mRS score of one non-recanalized patient was 4 at the 3 months follow-up. Conclusion The embolectomy effect is good whom using Solitaire AB device for acute occlusion occurred in the intracranial artery M2 or A3 segment. Its efficacy,safety,and indications still need to be further explored in a larger sample controlled trial.