1.To impel the development of medical science and technology embarking from the science and technology of the people's Livelihood
Chinese Journal of Medical Science Research Management 2010;23(1):10-12
Embarking from the people's livelihood science and technology, it is the important direction of new time health work to impel the medicine science and technology to serve the people's livelihood and to develop the people's livelihood. And it is also the request inevitably of the reform of health and medical community institutional. This article discussed the basic content of the people's livelihood science and technology, expounded that the medicine is the important component of the people's livelihood science and technology and has an important position in the development of the people's livelihood science and technology. At the same time, the article analyzed the problems which exist in the service of people's livelihood, of medicine science and technology in the current. And it was proposed that the policy should be reformed and innovated to speeds up the medical science and technology service of people's livelihood.
2.Imaging Manifestations of Pneumocystis Carinii Pneumonia in AIDS(A Report of 18 Cases)
Hengrui SHI ; Jianmin ZHAO ; Ming JIANG
Journal of Practical Radiology 2001;0(05):-
Objective To study the X-ray and CT findings of pneumocystis carinii pneumonia(PCP)in AIDS.Methods 18 cases with PCP in AIDS proved by clinic and pathologically were collected.HIV antibody was positive in all cases.Chest radigraphy and CT scan were taken in all cases.The imaging findings were analysed.Results The typical features of PCP on radiography and CT included unsymmetric diffuse mesh or reticulo-nodular changes,symmetric ground-glass opacification and many more even lobar consolidations which distributed in bilateral hilar regions and middle-lower lung fields.The atypical manifestations included cystic lesions,lobar consolidation,hilar and/or mediastinal adenopathy,pleural effusion,pneumothorax,atelectasis,mass and cavity-mass.Conclusion Plain chest film and CT scan are of important value in diagnosis of PCP.It is possible to diagnose PCP in patients with typical imaging manifestations positive HIV and in combination with clinical data.
3.Effects of Hirsutella Sinensis Strain Fermentation on The Proliferation of T and B Lymphocyte in Mouse
He HUANG ; Jianmin JIANG ; Huiying FU
Journal of Zhejiang Chinese Medical University 2006;0(04):-
[Objective] To observe the proliferation of T and B Lymphocyte in mouse after treated by Hirsutella sinensis strain fermentation.[Methods] Mice were treated with 1.0g?kg-1,0.1g?kg-1 of Hirsutella sinensis strain fermentation by intragastric administration.The proliferation of T and B Lymphocyte from the spleen of mouse is detected by the MTT assay .[Results] Hirsutella sinensis strain fermentation and Cordyceps Sinensis can distinctly increasse the stimulation index (SI) of T and B lymphocyte transformation.[Conclusion] Hirsutella sinensis strain fermentation and Cordyceps Sinensis are able to enhance immune function of normal mouse.
4.Changes in body shape,heart rate and blood pressure of 76 elderly women after aerobic exercise for 24 weeks
Tao JIANG ; Jianmin LI ; Jin HE
Chinese Journal of Tissue Engineering Research 2007;0(17):-
To observe the effect of aerobic exercise on the body shape,cardiovascular,physiology and biochemical indexes of elderly women,we trained 76 old women (volunteers,mean age 58 years old) from urban area of Yulin from 14th July 2005 to 14th January 2006,60 minutes every time,3 times a week. The heart rate during exercise was controlled within 110-125 times per minute. The changes in their body shape (body mass and waistline),cardiovascular function (resting heart rate and blood pressure) and biochemical indexes before and after exercise were observed. The results showed that after 24 weeks of aerobic exercise,the body mass and waistline of the subjects were decreased compared with that before exercise (P
5.Informatization of health appropriate technologies
Yanli LIU ; Jianmin JIANG ; Senxiang LIN ; Libo JIANG
Chinese Journal of Medical Science Research Management 2012;25(2):131-132
Health appropriate technologies are applied nationwide in our country and have produced good results. But the informatization of health appropriate technologies lags behind and is still at a preliminary stage.As the network of Zhejiang basic health appropriate technologies has been estabished,this paper discusses some issues related with the informatization of health appropriate technologies.
6.MRI and pathological discrimination of early pyogenic spondylitis from brucella spondylitis
Tao LIU ; Jianmin SUN ; Xingang CUI ; Zhensong JIANG
Chinese Journal of Tissue Engineering Research 2014;(4):499-504
BACKGROUND:Pathological examination and MRI have been widely used in clinic, but their combination is rarely reported in discrimination of early spine infections.
OBJECTIVE:To determine the accuracy of pathology and MRI for discrimination between early pyogenic spondylitis and brucella spondylitis.
METHODS:Twenty-two patients with pyogenic spondylitis and 20 patients with brucella spondylitis who had CT-guided percutaneous biopsy and MRI of the spine were retrospectively reviewed. Pathological observations included structure and activity of bone lesions, tissue cells and their main components;MRI observations included signal and sign changes at lesion sites. Statistical analysis was performed with the chi-square test.
RESULTS AND CONCLUSION:The patients with pyogenic spondylitis had a significantly higher incidence of pathological and MRI findings as fol ows (P<0.05):neutrophil infiltration;intervertebral disc abnormal signal, location of vertebral body lesions anterior+posterior, obviously shape change in the vertebral body, paraspinal abnormal signal, presence of intraosseous or paraspinal abscess. Pathological and MRI examination was accurate for early differentiation of pyogenic spondylitis from brucella spondylitis.
7.Apixaban for prevention of venous thromboembolism after major orthopedic surgery: a Meta-analysis
Jianmin WANG ; Liying CAO ; Shengping YANG ; Mingjing JIANG ; Guan WANG
Chinese Journal of Trauma 2013;29(10):960-965
Objective To systematically assess the clinical efficacy and safety of apixaban versus enoxaparin in the prevention of venous thromboembolism (VTE) after major orthopedic surgery.Methods Based on the principles and methods of Cochrane systematic review,the Cochrane Library,PubMed,EMBASE,Chinese Bio-medicine Database,China Journal Full-text Database,VIP Database were searched from their establishment to March 2012 in whatever languages.Related journals were handsearched as well.Randomized controlled trials (RCTs) of comparing apixaban and enoxaparin in the prevention of venous thromboembolism after major orthopedic operation were included.Cochrane Collaboration' s tool was used for assessing risk of bias in the included trials.Cochrane Collaboration' s software RevMan 5.1 was used for statistical analysis.Results Four RCTs totaling 12 897 patients were included.Apixaban treatment showed significant differences in aspects of total VTE and all-cause mortality [relative risk (RR) =0.63,95% CI(0.41,0.96)],major VTE [RR =0.59,95% CI(0.19,0.98)] and symptomatic deep vein thrombosis (DVT) [RR =0.50,95% CI(0.26,0.97)] when compared with enoxaparin,but the difference in fatal pulmonary embolism was insignificant[RR =1.57,95% CI(0.41,5.99)].For patients undergoing total knee arthroplasty,apixaban was associated with significantly fewer major bleeding events[RR =0.55,95% CI(0.32,0.96)] and fewer total bleeding events[RR =0.79,95% CI(0.66,0.95)] than enoxaparin.For patients undergoing total hip replacement,however,the two treatments revealed no statistically significant differences.With regard to the incidence of drug-related serious adverse events,the two treatments displayed no significant difference[RR =0.97,95% CI(0.59,1.58)].Conclusion Apixaban is effective in the prevention of VTE after major orthopedic surgery and can significantly reduce the risk of postoperative VTE.
8.System model for transfer and application of the appropriate health technologies in rural areas
Jianmin JIANG ; Qisheng GAO ; Wei ZHU ; Zhijun XIA ; Liang ZHANG
Chinese Journal of Medical Science Research Management 2014;27(2):155-158
Considering the core concept of the system theory,the author describes the conception,components and main functions of the subjects,the objects and behavioral factors for the popularization and application of appropriate health technologies.This theoretically built up the system model for transfer and application of the appropriate health technologies in Chinese rural areas.
9.Spinal sagittal imbalance in patients with osteoporotic vertebral compression fractures
Xiangwei ZHANG ; Jianmin SUN ; Xingang CUI ; Zhensong JIANG ; Jun DONG
Chinese Journal of Tissue Engineering Research 2014;(26):4224-4228
BACKGROUND:The reasons for spinal imbalance include spinal deformity, spinal degenerative disease osteoporotic vertebral compression fractures. We believe that the power factor (back muscle) plays a key role in spinal sagittal imbalance. OBJECTIVE:To analyze the reasons for spinal sagittal imbalance by observing clinical manifestations and therapeutic outcomes in patients with osteoporotic vertebral compression fractures. METHODS:A total of 41 patients with osteoporotic compression fractures combined with spinal sagittal imbalance were retrospectively analyzed from January 2012 to May 2013. Al patients were subjected to percutaneous bal oon vertebroplasty under local anesthesia. Before treatment, they received bone density, standing ful-spine lateral X-ray, CT and MR imaging with injured vertebrae as the center. Using standing ful-spine radiographs, the height of anterior border of the injured vertebrae, Cobb angle of kyphosis and improved angle, wedging angle of the injured vertebrae and improved angle were measured. The patients underwent weight loading test and walking test. Preoperative and postoperative data were compared. RESULTS AND CONCLUSION:The patients affected spinal sagittal imbalance symptoms, so the walking distance was significantly shorter than that postoperatively (P<0.05). Moreover, the time of weight loading test was significantly shorter than that postoperatively (P<0.05). In standing ful-spine radiographs, the average difference of Cobb angle was (10.01±0.76)°. The mean difference of vertebral wedging improvement was (4.84±0.40)° (P<0.05). Al patients were fol owed up. Low back pain and sagittal imbalance symptoms were relieved. No severe complications appeared after percutaneous bal oon vertebroplasty. Results indicated that patients with osteoporosis compression fractures can affect the symptoms of spinal sagittal imbalance, which is not only induced by wedging of the injured vertebra. In addition, after percutaneous bal oon vertebroplasty, imbalance symptoms are apparently improved, suggesting that back pain after spinal fracture limits back muscle strength and is an important cause for spinal sagittal imbalance.
10.The predictive model of carotid angiopathy set from randomly sampled community data
Lusha TONG ; Wenhong JIANG ; Shenqiang YAN ; Min LOU ; Jianmin ZHANG
Chinese Journal of Emergency Medicine 2014;23(7):801-805
Objective To establish a practical and effective predictive model for predicting carotid plaque/thickened intima,and to provide a novel perspective for stroke screening.Methods A retrospective analysis of the community screening data collected from September 2012 to March 2013 was performed.The data of blood pressure,serum lipid profile and fasting blood glucose and ultrasonographic checks of carotid artery were documented.One thousand subjects were randomly sampled from totally 14 226 individuals and divided into 2 groups according to the presence of carotid plaque/thickened intima.Analysis of relevant data of subjects with Logistic regression were performed.Predictive model was established according to the odds ratio for each risk factor and evaluated by C statistics.Results In the randomly sampled 1000 subjects,164 ones were found to be with carotid plaque/thickened intima.The mean age was (60.23 ± 10.09) years old,110 (67.1%) were male.Smoker,hypertension,angina pectoris,diabetes and hyperlipidemia were seen more often in the subjects with carotid plaque/thickened intima.Logistic regression analysis showed the independent risk factors for carotid plaque/thickened intima included advanced age (OR =1.15,95% CI:1.12-1.84,P<0.01),male (OR=3.97,95%CI:2.49-6.33,P<0.01),smoking (OR=1.80,95%CI:1.24-2.56,P =0.002),diabetes (OR =1.80,95% CI:1.15-2.98,P =0.012),hypertension (OR =2.82,95% CI:1.15-2.98,P < 0.01),high total cholesterol level (OR =1.63,95% CI:1.31-2.02,P < 0.01) and high LDL-C (low density lipoprotein-cholesterol) level (OR =1.70,95 % CI:1.35-2.14,P < 0.01).The advanced age was found to be the strongest predictive factor in this model.The C statistics of this model is 0.804,which overweighs other models previously reported.The optimal cutoff point for prediction was 3.5,with a sensitivity of 0.713 and a specificity of 0.757.Conclusion An practical and effective model for predicting carotid plaque/thickened intima established from sampling data of community residents is favorable for both stroke screening and primary stroke prevention.