1.To impel the development of medical science and technology embarking from the science and technology of the people's Livelihood
Chinese Journal of Medical Science Research Management 2010;23(1):10-12
Embarking from the people's livelihood science and technology, it is the important direction of new time health work to impel the medicine science and technology to serve the people's livelihood and to develop the people's livelihood. And it is also the request inevitably of the reform of health and medical community institutional. This article discussed the basic content of the people's livelihood science and technology, expounded that the medicine is the important component of the people's livelihood science and technology and has an important position in the development of the people's livelihood science and technology. At the same time, the article analyzed the problems which exist in the service of people's livelihood, of medicine science and technology in the current. And it was proposed that the policy should be reformed and innovated to speeds up the medical science and technology service of people's livelihood.
2.Imaging Manifestations of Pneumocystis Carinii Pneumonia in AIDS(A Report of 18 Cases)
Hengrui SHI ; Jianmin ZHAO ; Ming JIANG
Journal of Practical Radiology 2001;0(05):-
Objective To study the X-ray and CT findings of pneumocystis carinii pneumonia(PCP)in AIDS.Methods 18 cases with PCP in AIDS proved by clinic and pathologically were collected.HIV antibody was positive in all cases.Chest radigraphy and CT scan were taken in all cases.The imaging findings were analysed.Results The typical features of PCP on radiography and CT included unsymmetric diffuse mesh or reticulo-nodular changes,symmetric ground-glass opacification and many more even lobar consolidations which distributed in bilateral hilar regions and middle-lower lung fields.The atypical manifestations included cystic lesions,lobar consolidation,hilar and/or mediastinal adenopathy,pleural effusion,pneumothorax,atelectasis,mass and cavity-mass.Conclusion Plain chest film and CT scan are of important value in diagnosis of PCP.It is possible to diagnose PCP in patients with typical imaging manifestations positive HIV and in combination with clinical data.
3.Effects of Hirsutella Sinensis Strain Fermentation on The Proliferation of T and B Lymphocyte in Mouse
He HUANG ; Jianmin JIANG ; Huiying FU
Journal of Zhejiang Chinese Medical University 2006;0(04):-
[Objective] To observe the proliferation of T and B Lymphocyte in mouse after treated by Hirsutella sinensis strain fermentation.[Methods] Mice were treated with 1.0g?kg-1,0.1g?kg-1 of Hirsutella sinensis strain fermentation by intragastric administration.The proliferation of T and B Lymphocyte from the spleen of mouse is detected by the MTT assay .[Results] Hirsutella sinensis strain fermentation and Cordyceps Sinensis can distinctly increasse the stimulation index (SI) of T and B lymphocyte transformation.[Conclusion] Hirsutella sinensis strain fermentation and Cordyceps Sinensis are able to enhance immune function of normal mouse.
4.Changes in body shape,heart rate and blood pressure of 76 elderly women after aerobic exercise for 24 weeks
Tao JIANG ; Jianmin LI ; Jin HE
Chinese Journal of Tissue Engineering Research 2007;0(17):-
To observe the effect of aerobic exercise on the body shape,cardiovascular,physiology and biochemical indexes of elderly women,we trained 76 old women (volunteers,mean age 58 years old) from urban area of Yulin from 14th July 2005 to 14th January 2006,60 minutes every time,3 times a week. The heart rate during exercise was controlled within 110-125 times per minute. The changes in their body shape (body mass and waistline),cardiovascular function (resting heart rate and blood pressure) and biochemical indexes before and after exercise were observed. The results showed that after 24 weeks of aerobic exercise,the body mass and waistline of the subjects were decreased compared with that before exercise (P
5.Informatization of health appropriate technologies
Yanli LIU ; Jianmin JIANG ; Senxiang LIN ; Libo JIANG
Chinese Journal of Medical Science Research Management 2012;25(2):131-132
Health appropriate technologies are applied nationwide in our country and have produced good results. But the informatization of health appropriate technologies lags behind and is still at a preliminary stage.As the network of Zhejiang basic health appropriate technologies has been estabished,this paper discusses some issues related with the informatization of health appropriate technologies.
6.The trend of change and clinical significance of early-phase inflammatory indices after cervical fixation
Chen LIANG ; Jianmin SUN ; Xingang CUI ; Zhensong JIANG ; Tao LI
Chinese Journal of Tissue Engineering Research 2015;(53):8560-8566
BACKGROUND:The infection after spinal internal fixation was its serious complications. A number of studies have shown that erythrocyte sedimentation rate and C-reactive protein are of great importance in judging infections. OBJECTIVE:To analyze the trend of change of erythrocyte sedimentation rate and C-reactive protein for patients without infection after the cervical fixation. METHODS:Total y 56 patients, who underwent cervical fixation from October 2013 to July 2014, were retrospectively analyzed, and then divided into anterior cervical group (n=29) and posterior cervical group (n=27). Patients in the anterior cervical group underwent anterior cervical decompression bone graft internal fixation. Patients in the posterior cervical group underwent posterior cervical unilateral open door decompression internal fixation. The peripheral blood was col ected before fixation and at the early morning of the 1, 3, 6, 9 days after fixation. Erythrocyte sedimentation rate and C-reactive protein values were determined. The fol ow-up of patients was more than one year. Signs of infection did not appear. RESULTS AND CONCLUSION:(1) General rule:After the cervical fixation, the erythrocyte sedimentation rate was increased significantly and reached a peak on postoperative day 6. The peak level gradual y decreased but has not returned to normal at the 9 postoperative days. The C-reactive protein increased significantly on the first postoperative day and reached a peak on postoperative day 3. The peak level rapidly decreased but has not returned to normal at the 9 postoperative days. The level of erythrocyte sedimentation rate of patients in the posterior cervical group was significantly higher than that in the anterior cervical group at 3, 6 and 9 days after internal fixation (P<0.05). There was no significant difference in the C-reactive protein between these two groups (P>0.05). (2) These results demonstrate that C-reactive protein is an important indicator of monitoring the inflammatory response of patients after cervical internal fixation, which was conductive to the judgment of early infection after internal fixation. The abnormal inflammatory indices of erythrocyte sedimentation rate and C-reactive protein do not suggest a presence of blade infection after internal fixation. C-reactive protein can reach the peak at 3 days after fixation. It is recommended to check blood at 2 and 3 days. If there is no apparent rebound, then the possibility of infection is smal . It may indicate the presence of infection if the inflammatory indices increased again or decreased slowly after the decrease.
7.CT Features of Brain Lesions in AIDS
Jianmin ZHAO ; Wen LI ; Hengrui SHI ; Ming JIANG
Journal of Practical Radiology 2001;0(07):-
Objective To discuss the CT characteristics of AIDS's brain common disease,so that to improve the diagnostic level.Methods CT features of brain lesions in 25 patients with AIDS were retrospectively analyzed.Results Acute HIV encephalitis(n=6),CT features included low density at the basis festival area and the ventriculi laterals,no enhancement on contrast-enhanced scan in 1 case.Subacute HIV brain illness(n=5),CT images showed different degree of atrophy.Toxoplasmosis(n=4),CT images showed iso-dense tubercles with edema in the deep part of brain white matter or iso-dense circle at the edema area.Cytomegalovirus encephalitis(n=3),CT images showed symmetrical low density at bilateral cerebral occipital lobe,internal capsule and thalamus.Progressive multifocal leukoencepathy(n=3),CT showed multiple low density at the inferior surface of brain cortex,the gyri close of focus was clearer,and far of tapetum room system.Mixed infectious(n=4),mixed CT characteristics.Conclusion CT is beneficial in the differential diagnosis of brain disease in AIDS.
8.Study on the construction of policy system for the application of appropriate health technologies in rural areas
Jianmin JIANG ; Wei ZHU ; Zhijun XIA ; Jie SHEN ; Xin WEN
Chinese Journal of Medical Science Research Management 2012;25(3):175-178
To enhance the capacity for extending and applying appropriate health technologies in rural areas in China,this paper proposes a supportive policy system that incoperates macro,average and microlevels. Thepolicysystemfocusesonorientation, incentives, regulationsand standardization,and its objectives and measures of each level are described.The policy system will contribute to the sustainable development rural health work.
9.The predictive model of carotid angiopathy set from randomly sampled community data
Lusha TONG ; Wenhong JIANG ; Shenqiang YAN ; Min LOU ; Jianmin ZHANG
Chinese Journal of Emergency Medicine 2014;23(7):801-805
Objective To establish a practical and effective predictive model for predicting carotid plaque/thickened intima,and to provide a novel perspective for stroke screening.Methods A retrospective analysis of the community screening data collected from September 2012 to March 2013 was performed.The data of blood pressure,serum lipid profile and fasting blood glucose and ultrasonographic checks of carotid artery were documented.One thousand subjects were randomly sampled from totally 14 226 individuals and divided into 2 groups according to the presence of carotid plaque/thickened intima.Analysis of relevant data of subjects with Logistic regression were performed.Predictive model was established according to the odds ratio for each risk factor and evaluated by C statistics.Results In the randomly sampled 1000 subjects,164 ones were found to be with carotid plaque/thickened intima.The mean age was (60.23 ± 10.09) years old,110 (67.1%) were male.Smoker,hypertension,angina pectoris,diabetes and hyperlipidemia were seen more often in the subjects with carotid plaque/thickened intima.Logistic regression analysis showed the independent risk factors for carotid plaque/thickened intima included advanced age (OR =1.15,95% CI:1.12-1.84,P<0.01),male (OR=3.97,95%CI:2.49-6.33,P<0.01),smoking (OR=1.80,95%CI:1.24-2.56,P =0.002),diabetes (OR =1.80,95% CI:1.15-2.98,P =0.012),hypertension (OR =2.82,95% CI:1.15-2.98,P < 0.01),high total cholesterol level (OR =1.63,95% CI:1.31-2.02,P < 0.01) and high LDL-C (low density lipoprotein-cholesterol) level (OR =1.70,95 % CI:1.35-2.14,P < 0.01).The advanced age was found to be the strongest predictive factor in this model.The C statistics of this model is 0.804,which overweighs other models previously reported.The optimal cutoff point for prediction was 3.5,with a sensitivity of 0.713 and a specificity of 0.757.Conclusion An practical and effective model for predicting carotid plaque/thickened intima established from sampling data of community residents is favorable for both stroke screening and primary stroke prevention.
10.Apixaban for prevention of venous thromboembolism after major orthopedic surgery: a Meta-analysis
Jianmin WANG ; Liying CAO ; Shengping YANG ; Mingjing JIANG ; Guan WANG
Chinese Journal of Trauma 2013;29(10):960-965
Objective To systematically assess the clinical efficacy and safety of apixaban versus enoxaparin in the prevention of venous thromboembolism (VTE) after major orthopedic surgery.Methods Based on the principles and methods of Cochrane systematic review,the Cochrane Library,PubMed,EMBASE,Chinese Bio-medicine Database,China Journal Full-text Database,VIP Database were searched from their establishment to March 2012 in whatever languages.Related journals were handsearched as well.Randomized controlled trials (RCTs) of comparing apixaban and enoxaparin in the prevention of venous thromboembolism after major orthopedic operation were included.Cochrane Collaboration' s tool was used for assessing risk of bias in the included trials.Cochrane Collaboration' s software RevMan 5.1 was used for statistical analysis.Results Four RCTs totaling 12 897 patients were included.Apixaban treatment showed significant differences in aspects of total VTE and all-cause mortality [relative risk (RR) =0.63,95% CI(0.41,0.96)],major VTE [RR =0.59,95% CI(0.19,0.98)] and symptomatic deep vein thrombosis (DVT) [RR =0.50,95% CI(0.26,0.97)] when compared with enoxaparin,but the difference in fatal pulmonary embolism was insignificant[RR =1.57,95% CI(0.41,5.99)].For patients undergoing total knee arthroplasty,apixaban was associated with significantly fewer major bleeding events[RR =0.55,95% CI(0.32,0.96)] and fewer total bleeding events[RR =0.79,95% CI(0.66,0.95)] than enoxaparin.For patients undergoing total hip replacement,however,the two treatments revealed no statistically significant differences.With regard to the incidence of drug-related serious adverse events,the two treatments displayed no significant difference[RR =0.97,95% CI(0.59,1.58)].Conclusion Apixaban is effective in the prevention of VTE after major orthopedic surgery and can significantly reduce the risk of postoperative VTE.