BACKGROUND:At present, there are many clinical trials concerning plate fixation and smal splint for distal radius fracture, but there is lack of systemic evaluation.
OBJECTIVE:To evaluate the curative effect of the plate fixation and smal splint in the treatment of intraarticular fractures of the distal radius.
METHODS:We retrieved the Chinese biomedical database (1979-2008), China National Knowledge Infrastructure (1979-2008), VIP database (1989-2008) and Wanfang Digital Periodical Group (1998-2008). Of them, China National Knowledge Infrastructure contained Chinese periodical databases, important meeting ful-text databases, and Master-Doctor thesis database. Foreign databases included PubMed (1966-2008), EMbase (1980-2008) and the Cochrane Library (2008, 4th). The ful text that could access was supplemented by manual search back issues of Traditional Chinese Medicine, Tianjin University Library repository. Clinical randomized control ed trials addressing plate fixation with smal splint in the treatment of intraarticular distal radius fractures were col ected. The data were extracted independent by two evaluators and methodological quality assessment was performed. According to the search strategy and data col ection methods, 363 English articles and 488 Chinese articles were found, including 401 periodical literatures, 79 conference proceedings, and 8 theses. After reading title, abstract, ful text, 12 articles met the inclusion criteria. Meta analysis was conducted with RevMan 5.0.20 software provided by the Cochrane Col aboration Network.
RESULTS AND CONCLUSION:The evaluation of this system involves locking compression plate, normal internal fixation with plate, smal splints and plaster external fixation methods. Meta analysis of the results shows that the curative effects of locking compression plate in the treatment of intraarticular fracture of distal radius were better than that of common plate, smal splint or gypsum. Moreover, there were few complications. There is no significant difference in the effects between common plate fixation in treatment of intraarticular fracture of distal radius and the fixation with smal splint or gypsum.

One cases of vertically fractured molar was treated by following methods:the gap was exparded,the furcation lesion was drained;then a fixed prosthesis was inserted to restore the affected area.No symptom was observed in 2-year follow-up.

Objective To observe the correlation of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) appearances and blood stasis syndrome in breast cancer.Methods The clinical data of 100 patients with breast cancer confirmed by operation and pathology were retrospectively reviewed.70 cases without blood stasis syndrome,30 cases with blood stasis syndrome.All the cases underwent MRI using PHILIPS Achieva 1.5T magnetic resonance scanner before surgery.Results In no blood stasis group,76.67％ inhomogeneous enhancement,edge enhancement 43.33％,spiculation proportion 50.00％,which were significantly lower than those in the blood stasis group (88.57％,75.71％,83.33％).The mass ratio of the shape between the two groups had no significant difference (P ＞ 0.05).No blood stasis group and stagnation of blood group TIC curve was mainly type Ⅳ,type Ⅲ curve ratio of no blood stasis group (3.33％) was significantly lower than blood stasis group(12.86％) (P ＜0.01).In blood stasis group,Emax/1 and tumor size were higher than without blood stasis syndrome group.the percentage of V per minute outflow of blood stasis group was lower than without blood stasis syndrome group.Conclusion The clinician should make a preliminary evaluation of the prognosis before operation,in order to timely and reasonably choose the method of integrated traditional Chinese and Western medicine.

OBJECTIVE:To establish a method for the assaying of danazol in anti-hyperplasia of mammary glands cream.METHODS:The UV-spectrophometry was adopted to determine the content of dianozol with the wavelength at285nm.RESULTS:The dianzol was in linear relationship within the concentration range of5～25?g/ml(r=0.9999).The average recovery rate was99.2%(RSD=0.32%,n=5).CONCLUSION:The method is simple,rapid and accurate,which is suitable for the content determination and quality control of the preparation.

[Objective] To observe the proliferation of T and B Lymphocyte in mouse after treated by Hirsutella sinensis strain fermentation.[Methods] Mice were treated with 1.0g?kg-1,0.1g?kg-1 of Hirsutella sinensis strain fermentation by intragastric administration.The proliferation of T and B Lymphocyte from the spleen of mouse is detected by the MTT assay .[Results] Hirsutella sinensis strain fermentation and Cordyceps Sinensis can distinctly increasse the stimulation index (SI) of T and B lymphocyte transformation.[Conclusion] Hirsutella sinensis strain fermentation and Cordyceps Sinensis are able to enhance immune function of normal mouse.

Objective To report the treatment of intracranial fusiform or wide-necked aneurysms with combined endovascular stenting and Guglielmi detachable coils packing, and to evaluate its indication, technique, outcome, and complications. Methods The coronary stents were implanted across the necks of 5 fusiform aneurysms and 12 wide-necked aneurysms. Microcatheters were introduced into the aneurysmal sac through stent mesh, and GDCs were used to embolize the aneurysms. Results The stents were deployed in 16 cases, and total occlusion was obtained in 13 cases,while more than 90% in 3 cases. One aneurysm was embolized with GDCs alone after the attempt of stenting was failed. All the patients recovered well with patency of the parent arteries. Conclusion Endovascular therapy combined with stent implantation and microcoil placement may be a valid alteration for the treatment of intracranial fusiform or wide-necked aneurysms. Further study was necessary for long-term outcome.

OBJECTIVE To investigate the properties of nosocomial infections among acute stroke victims,analyze the risk factors associated with these infections,and find out effective methods of care and management.METHODS Between Jan 2003 to Dec 2006,428 cases of stroke victims were studied to analyze the special properties and risk factors related to hospital infections among them.RESULTS Their nosocomial infection rate was 8.93%,repetitive infection rate was 9.41%,and the top five infected sites were the lower respiratory tract,digestive tract,urinary tract,upper respiratory tract and skin,with their respective rates as 47.66%,17.76%,15.19%,9.81%and 6.31%.The occurrence of hospital infections was associated with stroke as well as the quality of the nursing care process,invasive procedures,duration of stay in the hospital,dietary conditions,etc.CONCLUSIONS Nosocomial infection is still a high frequent complication in cerebral stroke and those related factors should be paid attention.To effectively decrease nosocomial infections related to stroke,it is necessary to improve nursing care and supervision as well as control over the quality of care.

Purpose:To explore the clinical feature,and treatment of primary cervical lymphoma. Methods:Clinical data and follow-up survey data of 26 cases were retrospectively analyzed with SSPS software. Results:Primary cervical lymphoma could occur in any age group of women. The misdiagnosis rate was as high as 57.69% (15/26 case).Three of 26 patients died,the five years survival rate was 88.46%.Conclusions:Primary cervical lymphoma is rare,which was very often misdiagnosised. The treatment consisted of an combination of chemotherapy,operation and radiotherapy,which could improve curative results and reduce relapse.

Mucus secreted mainly by epithelial goblet cells and submucosal glands covering the respiratory tract plays an important role in the protection from external aggressions, such as solid particles, pathogens and chemical agents by mucociliary clearance. The viscoelastic properties of mucus are mainly determined by the presence of extensively-glycosylated high molecular weight mucins. A lot of factors influence the expression and secretion of mucins in airway, lead to mucus overproduction, which is a distinguishing feature of chronic obstructive pulmonary disease (COPD) and causes disruption of the mucociliary clearance function, resulting in airway block, chronic infection and death.

Objective To investigate the safety and efficacy of domestic contrast iodixanol injection in the application of interventional neuroradiology. Methods A total of 442 patients from 11 research centers using iodixanol injection for whole brain DSA examination or interventional therapy were enrolled in a prospective,multicenter,and non-controlled clinical trial. The recording and evaluation indicators included the adverse reactions after drug treatment,changes of creatinine and urea nitrogen indicators before and after drug treatment,DSA types,DSA effects,the dosage of contrast agent,etc. The renal function damage, incidence of adverse drug reactions,and image quality were counted and analyzed. Results All the 442 patients were completed the examination or treatment. (1)All the results of intraoperative angiography achieved excellent,including 98. 2% (n = 434)were excellent and 1. 8% (n = 8)were good. There were significant differences in the comparison of angiographic results in the 4 different types of DSA (SIEMENS,PHILIPS,GE,and TOSHIBA)(χ2 = 31. 518,P < 0. 001 ). (2 )Only 1 patient had increased serum creatinine > 44. 2 μmol / L. There was no urea nitrogen abnormality of clinical signifi-cance. None of the patients had renal insufficiency. (3)Three patients had adverse drug reaction (0. 7%) during procedure,including 2 patients had dermal allergic reactions and 1 patient had transient blurred vision. Conclusion Domestic iodixanol injection is safe and effective and has less adverse reaction in the clinical application of interventional neuroradiology. The different types of DSA may impact on the contrast image quality.