Objective To observe the clinical effect of ilaprazole in the treatment of peptic ulcer.Methods 100 patients with peptic ulcer were randomly divided into omeprazole group and ilaprazole group,50 cases in each group.The patients were given omeprazole or ilaprazole combined with amoxicillin and clarithromycin.The treatment effects and clinical symptom relief satisfaction rate were compared between the two groups.Results After treatment,the results under gastroscopy:in ilaprazole group,20 cases cured,16 cases healed,9 cases were effective and 5 cases were invalid.Those in omeprazole group were 14 cases,12 cases,12 cases,12 cases respectively.The differences between the two groups were statistically significant(U =3.78,P ＜ 0.05).The removal rate of Helicobacter pylori and clinical symptom relief satisfaction rate of ilaprazole group were significantly higher than those of the omeprazole group(x2 =3.84,4.57,P ＜ 0.05).Conclusion Ilaprazole can obtain good clinical effect in treatment of peptic ulcer,with high symptom relief satisfaction rate and clearance of Helicobacter pylori.

Objective To investigate the clinical efficacy of Fuzheng Huayu Capsule in the treatment of liver cirrhosis (decompensated) and its impact on quality of life in patients with TCM therapy research.Methods 160 cases of liver cirrhosis (decompensated) patients were chosen as research subjects.They were divided into experimental groupand control group according to random number table.Both groups used routine liver antiviral therapy,the experimental group was given Fuzhenghuayu tablets therapy,the control group only received conventional therapy.After 6 months of treatment,and treatment for the two groups of patients were evaluated quality of life conditions.Results Compared with before treatment,HA,LN,PC Ⅲ,Ⅳ-C of the indicators were significantly decreased,and the difference was statistically significant (t =10.89,15.88,10.42,12.38,4.41,9.27,4.97,6.55,all P ＜ 0.05).After the two groups of patients for the treatment of fibrotic indicators analysis found more significant decline in the observation group,the difference was statistically significant (t =5.32,3.88,5.25,5.01,all P ＜ 0.05).2 Compared with before treatment,ALT,AST levels of the two groups were significantly decreased,the difference had statistically significant (t =2.02,17.87,2.62,7.96,all P ＜0.05).for two groups of patients was compared with that total efficiency (87.50％ vs 66.25 ％),the difference was statistically significant (x2 =10.16,P ＜ 0.05).Compared with pre-treatment,two patients in the field of physiology,psychology field,the field of social relations,environmental areas and total score was significantly higher,the difference was statistically significant (t =13.94,12.37,11.12,10.71,16.45,8.60,6.54,8.35,4.86,8.04,all P ＜ 0.05) ; The two groups of patients after treatment compare the scores and scores found in the observation group was significantly more elevated,compared with the control group,the difference was statistically significant (t =4.97,3.81,4.98,2.56,5.05,all P ＜ 0.05).Conclusion In the treatment of hepatitis cirrhosis,Fuzheng Huayu Capsule can significantly improve the degree of liver fibrosis,improve the quality of life of patients and improve clinical outcomes.

BACKGROUND:Costal cartilage, auricular cartilage, materials for teeth and silica gel have been widely applied in rhinoplasty, but consequent adverse events, such as rejection, prosthesis displacement and implanted skin redness make the outcomes far from satisfaction. OBJECTIVE:To explore the effect of expanded polytetrafluoroethylene prosthesis for lower dorsum with small nasal septum.METHODS/DESIGN:This was a prospective, single-central, randomized, and open-label study that finished in the Qinghai University Affiliated Hospital, China. 100 patients hospitalized in the Department of Otorhinolaryngology for rhinoplasty between January 2014 and June 2015 were enrolled, and randomized into experimental and control groups (n=50 per group). The experimental group was subjected to the polytetrafluoroethylene prosthesis implantation, while the control group received the silica gel implantation. All patients were followed up for 12 months. The primary outcome measure was the postoperative satisfaction at 12 months. The secondary outcome measures were the changes of the nasal internal structure indexes, ultrasonic results of the nasal internal soft tissues and the incidence of adverse events. This study was approved by the Ethics Committee of the Qinghai University Affiliated Hospital and in accordance with the Declaration of Helsinki, formulated by the World Medical Association. All participants had signed the informed consents prior to participation in the study. DISCUSSION:Polytetrafluoroethylene prosthesis and silica gel both exhibit high biosafety in rhinoplasty. Compared with silica gel, the polytetrafluoroethylene prosthesis can effectively adjust the nasal appearance mini-invasively and obtain satisfactory outcomes;therefore, it is expected to be a substitute of filling materials applied in nasal plastic surgery.

Objective To investgate the pathogenesis clinical situation'and methods of diognosis and therapy of temporomandibular joint disorder.Methods Retrospectus was made on 100 cases of temporomandibular joint dis- order patients clinical situation,diagnosis and therapy during 1997-2006.Results The main patients were female, the percentage was 62%,and male's percentage was 38%;the age between 21 and 30 was pathogenic fastigium.The main pathogeny was occlusion and occlusion abnormal function,and the percentage was 56%.Clinical style:chaw muscle disorder genus(45 cases),joint structure disorder genus(29 cases) ,inflammation genus(20 cases),bone joint genus(6 cases).Conclusion The method of integrated therapy should be adopted,in order to alleviate pain and bur- den of abnormal joint,and renew joint's natural function.

OBJECTIVE: To observe the efficacy of Yiqi runchang decoction in the treatment of pediatric constipation. METHODS: 300 young children in out-patient department were randomly divided into treatment group and control group(n=150). Treatment group were treated with Yiqi runchang decoction made by our hospital and control group were given Wangshi baochi pills. Usage and dosage of drug for children were determined based on the age of children. After 20 days of treatment, the clinical efficacy and symptoms of two groups were observed, such as abdominal pain, abdominal distension, anorexia, feeble and perspire. RESULTS: After two treatment courses, treatment group was superior to control group in clinical efficacy and improvement of symptom(P

0.001). The elevation of ?_2m appeared before the abnormality of BUN, blood Cr and urine protein in some patients. It is considered that ?_2m in serum and urine is a sensitive index of the early lesion of renal function in diabetics.

Plasma angiotensin II (PA II )and aldosterone (PA) were measured in 89 cases of diabetes mellitus by means of radioimmunoassay, compared with 40 normal controls. The results showed that PA II and PA increased significantly in diabetic patients without complications and with ketoacidosis (P

OBJECTIVE:To study the strategy of technical innovation and the mode of R&D of pharmaceutical enterprises in China METHODS:Analysis was based on the domestic and foreign literature combined with the actual situation of pharmaceutical enterprises in China RESULTS & CONCLUSION:Pharmaceutical enterprises in China should be on the basis of their distinguishing feature to find out the points of breakthrough in technical innovation,and accordingly decide their strategies of technical innovation;In addition,they should adopt the appropriate mode of R&D in the light of specific conditions,which include their own features,the specialties of pharmaceutical industry and the environment of the market and technique

Non-operative treatment in 105 cases of acute traumatic intracranial hematomas confirmed by CT scan is reported. Results were satisfactory except in 6 cases in which operation was performed because of the worsening of their conditions. In this paper, the indication, method, and advantages of non-operative treatment are also discussed. We believe that the change of state of consciousness, size of hematoma, degree of shift of midline structures and cerebral contusion, and type of hematoma are decisive factors in making the choice of operative or non-operative treatment.

BACKGROUND: Health status of elderly people is an important problem concerned by the whole society. To find the way of preventing loss of functional status of daily life for elderly people is the key to generally improving the quality of life in elderly people.OBJECTIVE: To observe the main characteristics of function loss in healthy elderly people and analyze the influencing factors of the change of functional indexes in elderly people in normal functional status.DESIGN: Contrast observation; Logistic analysis.SETTING: Student's Office, Shangrao Normal College.PARTICIPANTS: All the data were from the sampling questionnaire survey on health status of 1 700 people including retired cadres and employees from 11 cities of Jiangxi province. The survey was conducted by Senile Physical Education Association of Jiangxi Province in January 2004.METHODS: The test was performed depending on 4 indexes in physical self-maintenance scale including dressing, taking food, bathing and toileting along with other indexes of shopping, calling, riding, going upstairs to the third floor, walking for 1 000 m, taking things by fingers and squatting & standing. These 11 indexes were used for evaluating the functional status of daily life in elderly people. According to international definition,people with difficulty in one or more indexes could be defined as ability loss of self-cave in daily life. The participants were demanded to give the score of difficulty in independently completing each activity including not difficult (1), somewhat difficult (2), very difficult (3), completely impossible (4). The total sum of 11 scores was defined as functional status index of daily life. Its value reflected the whole situation of functional status of daily life in elderly people. The higher the index was, the worse the functional status was. Comparison was conducted among groups of different gender and age, and Logistic regression analysis was used for evaluationand analysis.MAIN OUTCOME MEASURES: Evaluation of functional index, function loss rate of daily life, index in independent physical self-maintenance ability of daily life.RESULTS: ① Normal functional status of elderly people is various due to the different age, gender, constitution, marital status, living situation,employment history, economic status and education background etc. ② As far as function loss rate of daily life in healthy elderly people was concerned, male was higher than female, and people taking part-time jobs and rehired after retirement were higher than other retirees. When it came to loss rate of motor function of lower limbs, widowed people were higher than not widowed, and the higher the education, the better motor functional status of lower limbs the male had, while the situation was reversed for female.CONCLUSION: Loss rate of normal functional status of elderly people significantly decreases as their age increases, and it is relevant to the complexity and difficulty of activities of life. Normal functional status of elderly people is related to social support, economic status, psychological and mental status.