AIM: To study the anti-inflammatory effect of the Antivirus Oral Liquid(AOL) in experimental rabbit conjunctivitis model. METHODS: Rabbit's staphococcus aureus conjunctivitis models and cantharides tincture conjunctivitis models were made to observe different groups of animals' symptom of eye stimulation,negative rate of bacteria and conjunctiva histopathology.And then AOL compared with the effect of amphemycin gutta or Shumu(gutta.) RESULTS: It showed that AOL possessed significant anti-inflammatory effect on bacterial conjunctivitis.The negative rate of bacteria was more than 90% after being given AOL for 4 days successively.Compared with the models group,the hyperemia and edemda were markedly relieved.The result showed that AOL possessed significant anti-inflammatory effect on irritable conjunctivitis.The hyperemia and edema were markedly relieved at the second day after being given AOL,and the inflammatory symptoms had almost disappeared after being given AOL for 4 days successively. CONCLUSION: AOL has a good effect on the therapy of staphylococcus aureus conjunctivitis and cantharides tincture.