Objective To investigate the effect of carboprost tromethamine combined with oxytocin on postpartum hemorrhage of scarred uterus in late pregnancy, and to provide theoretical basis for the application of carboprost tromethamine combined with oxytocin. Methods From May 2015 to May 2017, 52 pregnant woman with postpartum hemorrhage with scarred uterus in late pregnancy in the sixth hospital in Beijing were divided into the control group and the observation group. The control group was treated with oxytocin, and the observed value was treated with progesterone tromethamine injection and oxytocin. Postpartum hemorrhage, the incidence of postpartum hemorrhage in the two groups were compared. Results The intraoperative blood loss, postoperative 2 h and postoperative 24 h bleeding in the observation group were significantly lower than those in the control group, the difference was statistically significant (P<0.05). The incidence of postpartum hemorrhage in the observation group was 3.85％, significantly lower than 11.54％ in the control group, the difference was statistically significant (P<0.05). Conclusion carboprost tromethamine combined with oxytocin in the treatment of postpartum hemorrhage in the pregnant woman with scarred uterus in late pregnancy is effective and can reduce the rate of postpartum hemorrhage and the amount of bleeding, so it is worthy of popularization and application.

Objective To analyze the effect of applying KTH [knowledge-attitude-belief practice model (KABP model), transtheoretical model of behavior (TTM) and health belief model (HBM)] integrated health education into nursing of elderly patients with hypertension in institutions in poor areas. Methods KTH integrated health education was established. Before the intervention and 12 weeks after intervention, the Questionnaire of Hypertension Knowledge, the Primary Hypertension Patients′Compliance Scale and Chinese version of the World Health Organization Quality of Life Questionnaire (WHOQOL-100) were used to investigate 84 cases of elderly patients with hypertension of four pension institutions in three poverty-stricken counties of Chaoyang city. Results After 12 weeks of intervention, the awareness rate of hypertension knowledge, compliance behavior and quality of life scores were higher than those before intervention, the complete awareness rate was 100.0% (84/84) vs. 3.5% (3/84);the high level of compliance behavior was 48.8%(41/48) vs.15.5%(13/84),the difference was significant (χ2=156.41, 86.27, P<0.01). The total score of quality of life was 86.95±5.41, higher than that before the intervention (76.93±6.60), the difference was statistically significant (t=8.662, P<0.01). Conclusions KTH integrated health education is an effective way to be applied in pension institutions of poor areas.

Objective To explore optimal effectiveness concentration of Iodophor(a iodic complex) disinfectant in order to reduce further the intrapartum infection rate of pericineum incision.Methods Pericineums of 4760 puerperants with lateral perineotomy were sterilized by 5% Iodophor disinfectant solution,these puerperants had child-birth in period from Jun 1998 to Aug,2002 in our hositpal,as experimental group.Other hositalized 3520 puerperants with lateral perineotomy during Mar.1996 to May 1998,their pericineums were sterilized by 0 5% Iodophor disinfectant solution,as control group.Results Intrapartum infection rate of operation-assisted labor,spontaneous delivery was lower in the experimental group than those of control group.There was obvisusly difference(P

The reduced level of high density lipoprotein (HDL) in plasma is a strong predictor of atherosclerotic vascular disease risk. However, like low density lipoprotein (LDL), HDL is readily oxidized by a variety of oxidants in vitro . This review briefly discussed about the susceptibility of HDL to oxidation, the site and physiologic oxidants of HDL oxidation in vivo ,structural change in oxidized HDL, as well as the influence of different changes in structure of oxidized HDL on the protective function of HDL against atherosclerosis.

ObjectiveTo discuss the application of clinical pathway in the health education for spinal cord injured patients in rehabilitation department. Methods56 patients with spinal cord injury were divided into 2 groups: treatment group and control group. Both groups were cared with holistic nursing. However, the health education to the treatment group was given by clinical pathway, while to the control group by traditional way. On the day of discharge, the health education standard and the satisfaction of patients were investigated. ResultsBoth the rates of standard in health education and satisfaction were more in treatment group than in control group. ConclusionApplication of clinical pathway can regulate the health educational behavior, improve the communication between nurses and patients, and the quality of nursing.

Objective To analyze the positive rate of autoantibodies in Xinjiang Uygur patients with different types of auto‐immune liver disease and its diagnostic value .Methods Fifty‐one Uygur outpatients and inpatients with of autoimmune liver disease in our hospital from October 2012 to October 2014 were selected ,including 20 cases of autoimmune hepatitis (AIH ,AIH group) and 31 cases of primary biliary cirrhosis (PBC ,PBC group) .The indirect immunofluorescence and Western blotting were used to detect the serum biochemical indexes and autoantobodies ,and the comparative analysis was performed .Results The levels of various bio‐chemical indexes in the two groups were increased ,in which ALT ,γ‐GT ,ALP and IgM levels had statistical difference between the two groups(P<0 .05) .The positive rates of ANA ,SMA ,LKM‐1 antibody ,LC‐1 antibody ,SDLA/LP antibody and AMA in the AIH group were 65 .0% ,40 .0% ,10 .0% ,5 .0% ,10 .0% and 5 .0% respectively ;the positive rates of ANA ,AMA and M2 subtype (AMA‐M2) in the PBC group were 61 .3% ,100 .0% and 96 .8% respectively .Conclusion The autoantibodies spectrum in Xinjiang Uygur patients with autoimmune liver diseases has certain characteristics .The autoantibodies spectrum detection has an important significance for the diagnosis ,classification and differential diagnosis of autoimmune liver diseases .

BACKGROUND:Studies have shown that inflammatory cytokines may influence the prognosis after myocardial infarction, and play an important role in the process of cardiac remodeling. The non-hematopoietic effects of
erythropoietin have been confirmed:erythropoietin can reduce the inflammatory reaction through bending with
the erythropoietin on the surface of target cel membrane, thus decreasing the reperfusion injury after myocardial ischemia.
OBJECTIVE:To observe the effect of recombinant human erythropoietin on the inflammatory factor expression during cardiac remodeling in rats with acute myocardial infarction.
METHODS: Sprague Dawley rat models of acute myocardial infarction were established through the ligation of the left anterior descending coronary artery. The rats were divided into five groups:sham operation group was
injected with normal saline;operation control group was injected with normal saline after modeling;SB203580 group was injected with highly selective p38 MAPK inhibitor SB203580 after modeling;erythropoietin group was injected with
erythropoietin after modeling;the erythropoietin+SB203580 group was injected with erythropoietin+SB203580 mixed solution after modeling. The tail vein blood samples were col ected before modeling, 1 day, 1 week, 2 weeks and 4 weeks after modeling, and then enzyme-linked immunosorbent assay was used to detect the levels of interleukin-1β, interlrukin-6 and tumor necrosis factor-α.
RESULTS AND CONCLUSION:There were no significant differences in the levels of interleukin-1β, interlrukin-6 and
tumor necrosis factor-αbetween groups before modeling (P>0.05). There were no significant differences in the levels of interleukin-1β, interlrukin-6 and tumor necrosis factor-αbetween different time points in the sham operation group (P>0.05), and the levels were highest at 1 day after modeling in the other four groups, and then decreased at 4 weeks after modeling (P<0.05). After modeling, the level of serum cytokines in the operation control group were higher than those in the other four groups, while level of serum cytokines in the sham operation group was lower than that in the other four groups (P<0.05);among the three groups intervened with drugs, level of serum cytokines was lower in the
erythropoietin+SB203580 group (P<0.05), while there was no significant difference in the level of serum cytokines between erythropoietin group and SB203580 group (P>0.05). Recombinant human erythropoietin can inhibit the expressions of inflammatory factors (interleukin-1β, interlrukin-6 and the tumor necrosis factor-α) during cardiac
remodeling after rat acute myocardial infarction, and the mechanism of recombinant human erythropoietin for inhibiting the expressions of inflammatory factors may related with the transforming growth factorβ1-TAK1-p38 MAPK signal pathway.

Objective To improve the knowledge of mammographic signs of sclerosing adenosis.Methods The X-ray and pathological features of sclerosing adenosis of 17 focuses in 15 cases proved by histology were reviewed in comparison with that of breast cancer.The study was put emphasis upon the difference between sclerosing adenosis and breast cancer on clinic and radiographs.Results On mammography,the lesions appeared as asymmetric and disseminated density in 5/17(29.4%),dense nodules in 10/17(58.8%),calcifications inside the lesions in 3 and focal architectural disorder combined with stellate constriction in 2/17(11.8%).Conclusion The sclerosing adenosis is easily confused with breast carcinoma on radiographic signs,the diagnosis would be combined with clinical history and palpation examination.

Objective To investigate the relationship between the activity of Na +/K +pump on RBC membrane and abnormal potassium transportation through cellular membrane in hypokalemic patients Methods Activity of RBC ATPase in 17 cases of hypokalemic paralysis patients and 16 cases of healthy controls was tested Results Activity of RBC ATPase was statistically higher in hypokalemic periodic paralysis (HOPP)group[( 25 6?3 5) ?mol?(10 7RBC) 1 ?h 1 ], and lower in nephridium oxidosis group [(1 9?0 8) ?mol?(10 7RBC) 1 ?h 1 ]than in control group[(6 2?0 9) ?mol?(10 7 RBC) 1 ?h 1 , P