1.Bibliometrics research of Tibetan medicine lamiophlomis rotate
International Journal of Traditional Chinese Medicine 2011;33(11):1017-1019
ObjectiveLamiophlomis rotate is the rare perfumes Tibetan medicine.This article aimed to explore the current research of Lamiophlomis rotate on the base of literature.MethodsEstablish database of researching literature on Lamiophlomis rotate in domestic published between 2000 and 2010.Results Altogether 210 articles distributed in 112 kinds of journals were found.These articles involved with 8 areas of clinical research(113 article),pharmacological research(18 article),component analysis(35 article),preparation process (15 article),breed and cultivation of seeds (4 article),new drug testing (3 article),biological characteristics and drug economics.32 articles gained fimancial assistance from fund.Three articles on breed and cultivation of seeds gained financial assistance from fund,occupying 75.00% of such research.Conclusion There were few articles published in core journals,besides relatively scattered distribution of researching institute and journals.Studies on breed and cultivation of seeds should be strengthened.
2.Clinical study on valsartan and simvastatin in early diabetic nephropathy
Hongdan LIU ; Jianhua LI ; Jing FAN
Chinese Journal of Primary Medicine and Pharmacy 2008;15(10):1597-1598
Objective To observe the effects and the functions of valsartan and simvastatin in early diabetic nephropathy. Methods A total of 80 patients with early diabetic nephropahy were randomly divided into two groups.The patients in control group(n=40)received valsartan at a dose of 80rag/day ,while in treated group(n=40)on the base of the same treatment as control group, added simvastatin 20 mg/everyrfight. To compare the differences of lipids,urine albumin excretion rate(UAER) and C-reactive protein(CRP) before or after treatments through 12 weeks. Re-sults The UAER of two groups decreased obviously after therapy,especially the treated group(P<0.01) ;the lipids and CRP also decreased evidently in the treated group (P<0.05). Conclusion The lipids, UAER, CRP of patients in early diabetic nephropathy could be down-regulated,with combined medication of the simvastatin and valsartan, and the injury of renal alleviated.
3.Establishment of a biostereometric system for measurement of breast volume
Lei SHAN ; Jianhua GAO ; Jihong FAN
Chinese Journal of Medical Aesthetics and Cosmetology 2001;0(03):-
Objective To establish the biostereometric system of breast volume measurement and to estimate the precision and reliability of the designed system. Methods Biostereometric system of breast volume measurement was built upon the biostereometrics based on computer stereo vision and image processing. One laser projector was used as illuminating source, two CCD cameras were mounted for photo-taken, a series of parallel points were provided through a piece of grating. The volumes of 12 female breast models were tested by water displacement (golden standard) and biostereometric analysis. Results The maximum size of marks we photographed was within 120 mm?140 mm?80 mm. The characters of the system was rapid, non-contact and noninvasive. The validity and reliability of determination of breast volume between biostereometric system and golden standard had no significant difference, compared to water displacement (P=0.473). Conclusions Biostereometric system of breast volume measurement will be suited for the clinical application. The study offers a noninvasive, non-contact, rapid and accurate morphologic method and provides a new theory foundation for morphological analysis.
4.Heart-lung transplantation for 4 patients with Eisenmenger’s syndrome
Huimin FAN ; Zhongmin LIU ; Jianhua GUO
Chinese Journal of Organ Transplantation 2003;0(05):-
Objective To summarize the experience of heart-lung transplantation.Methods Four patients with Eisenmenger’s syndrome underwent heart-lung homoplastic transplantation. All patients were complicated with severe pulmonary hypertension in New York Heart Association ( NYHA ) functional class IV. Cannulation for cardiopulmonary bypass consisted of a cannula in the high ascending aorta and separate vena caval cannulas. The heart-lung graft was moved into the chest, beginning with passage of the lung before the phrenic nerve pedicle. The bronchus was trimmed, leaving two cartilaginous rings proximal to the orifice of the upper lobe. The tracheal anastomosis was performed with a continuous 4-0 polypropylene suture, with the posterior portion continuously and anterior interrupted. The lungs were then ventilated (
5.Effects of Fluoxetine and Electroacupuncture on G-protein Level in Platelet Membrane from Patients with Major Depression
Yuqing SONG ; Dongfeng ZHOU ; Jianhua FAN
Chinese Mental Health Journal 2002;0(11):-
Objective: Affective disorder patients can be effectively treated by electro-acupuncture methods without many side effects, but the mechanism of the treatment is not known. The object of this study was to discover whether there is change of guanine-nucleotide-binding protein (G-protein) level in platelets membrane from major depression patients before and after treatment by fluoxetine and electro-acupuncture. Methods:We utilized selective antibodies to quantitate the levels of the G-protein ? subunits in platelets membrane of 78 major depression patients (24 received fluoxetine treatment, 24 received electo-acupuncture treatment and 30 received placebo treatment) and 30 matched comparison subjects.Result:Levels of both G?i and G?q of the patient groups were higher than matched normal comparison subjects before treatment of fluoxetine and electro-acupuncture,the level of G?i and G?q did not change after the treatment of fluoxetine, electro-acupuncture and placebo. The level of G?s wasn't significantly different with matched comparison subjects.Conclusion:The levels of G?i、G?q in platelets membrane from major depression patients are higher than normal, the high levels of G?i and G?q in platelets membrane may be a trait abnormality for major depression patients, not a state abnormality for major depression.
6.Application of Rasch analysis in clinical nursing examination
Xiufen CHEN ; Lin WANG ; Jianhua GE ; Juan FAN ; Hong LI
Chinese Journal of Practical Nursing 2010;26(7):9-11
Objective To evaluate the strictness and self-consistency of the charge nurses in the nurses examination using venipunctnre trocar operation as research object.Methods FACETS,the polyhedral Rasch software was used in the examination.Results The strictness and self-consistency of charge nurses were evidently different.Conclusions The variable strictness and self-consistency of the charge nurses in the examination leads to unreliability of the results.Developing a scientific and reliable evaluation system is essential to improve the ability of the teaching nurses and the student nurses as well as the hospital nursing quality.
7.Protective effect of intravenous infusion injection of safflor yellow and hydroxyl safflor yellow A on acute myocardial ischemia injury in rats
Jianhua FU ; Qiong ZHANG ; Changzheng FAN ; Jiangang LIU
International Journal of Traditional Chinese Medicine 2011;33(8):692-694
Objective The comparison research of protective effect between intravenous infusion injection of safflor yellow and hydroxyl safflor yellow A on acute myocardial ischemia injury in rats. Methods Qualified 60 male Wistar rats were divided into 5 groups at random (12 in each group):Blank control group, AMI model (treated with normal saline) group, intravenous infusion injection of safflor yellow (90 mg/kg) group, HSYA low dosage (20 mg/kg) group and high dosage (40 mg/kg) group. The acute myocardial ischemia injury in rats was induced by ligating the anterior descending coronary artery in Wistar rats and administered different dosage of safflor yellow and hydroxyl safflor yellow A with intraperitoneal injection. Myocardial infarction degree (MID) was calculated by detecting myocardial infarction area with nitroblue tetrazolium(NBT) assay. The changes of ST-elevation, CK-MB, cTnT, SOD activities and MDA contents were detected and analyzed. Results The intravenous injection of safflor yellow and HSYA low dosage group can significantly decreased ST-elevation [difference is (0.087?.022)mv,(0.091?.014)mv],MID[difference is (20.13?.17)%,(18.36+9.38)%], CK-MB [difference is (1460.70+219.73)U/L, (1472.72?85.61)U/L], cTnT[difference is (2.345?.883)ng/ml, (2.358?.843)ng/ml], and MDA [difference is(5.71 ?.67) mmol/ml, (5.76?.84)mmol/ml] contents in serum, increased SOD[difference is(58.27?.99)U/ml,(56.49+5.19)U/ml]activities in serum.Conclusion It showed that intra venous injection of safflor yellow and hydroxyl safflor yellow A had the same protective effect on acute myocardial ischemia injury in rats. Hydroxyl safflor yellow A is an important portion of safflor yellow.
8.A review of clinical characteristics and laboratory data of Alstr(o)m syndrome and two cases report
Jianhua LUO ; Ruiping YU ; Yan GU ; Bo LIU ; Yuanshuo FAN
Chinese Journal of Endocrinology and Metabolism 2011;27(11):897-900
Objective Alstr(o)m syndrome (AS) is a rare,autosomal recessive inherited disease characterized by various clinical manifestations.The aim of this study was to review the clinical characteristics and laboratory findings of AS.Methods Two cases of AS was reported.Combined with the clinical data of 7 cases of AS which had been reported in China,the clinical characteristics and laboratory findings of AS were reviewed.Results Visual disorder( median onset age:6.0 years ) and dysaudia( median onset age:10.3 years ) were found in 9 patients,short stature and obesity in 8 patients,acanthosis nigricans in 7 patients,diabetes mellitus( median onset age:14.5 years) in 6 patients,and heart disease in 4 patients; hyperuricemia was detected in 6 patients,hepatic dysfunction and hypertriglyceridemia in 5 patients.Conclusions Visual disorder was the first presentation in patients with AS.Deafness,obesity,diabetes,and short stature were common.These findings were helpful in making an early and accurate diagnosis and appropriate treatment.
9.Methods and effects of abdominal and pelvic shielding for pediatric chest CT examinations
Jianhua GU ; Xiuliang LU ; Weihai ZHUO ; Dunhuang FAN
Chinese Journal of Radiological Medicine and Protection 2014;34(4):298-301
Objective To investigate the methods and effects of abdominal and pelvic shielding for pediatric chest CT examinations.Methods The 705-D phantom made by Computerized Imaging Reference Systems (CIRS) was used to replace a 5-year-old child,thermoluminescent dosimeters were set in the abdomen and pelvis to measure the organ and tissue doses.Chest scans were conducted with the routine protocol for pediatric chest CT examinations.Doses to main organs and tissues in the abdomen and pelvis were measured after chest CT scans without lead apron,with lead apron covering anterior of the abdomen and pelvis and with apron wrapping same part,respectively.Results Absorbed doses to some abdominal organs near the irradiation field were up to several mGy in a procedure of pediatric chest CT examination.There were statistically significant differences among the dose values for three different scans at the same location (x2 =16.00,P < 0.05).Statistically significant difference was also found between the dose values for scans,which were measured with wrapping and covering approaches (Z =-2.52,P < 0.05).Compared to the doses in the condition of no shielding,the doses in testis and colon reduced by 71.2% and 42.3%,respectively,if the abdomen and pelvis was wrapped with a lead apron (0.35 mm Pb),and reduced by 55.9% and 26.1%,respectively,if the same lead apron was used to cover the anterior of the abdomen and pelvis.Conclusions In pediatric chest CT examinations,the use of a lead apron can effectively shield the abdomen and pelvis,and plays an important role in protection of the gonad and colon.The wrapping measure is worth being recommended.
10.Application of the double balloon device in labor induction for women with preeclampsia and eclampsia
Yanmei SUN ; Cuifang FAN ; Jianhua CHEN ; Zhizhen DUAN
Journal of Chinese Physician 2013;15(9):1187-1189
Objective To evaluate the efficacy and safety of labor induction by the double balloon device in women with preeclampsia and eclampsia.Methods Labor induction was carried out in 37 women with preeclampsia and eclampsia from July 2011 to November 2012.All the labor inductions were performed using the double balloon device.Results The cervical Bishop scores of 37 cases of patients with preeclampsia and eclampsia were significantly lower before using double balloon device [(3.38 ± 0.50) scores] compared with after using double balloon device [(6.44 ± 0.63) scores] with a statistically significant difference (t =23.54,P <0.01).Blood pressure had no obvious change before and after using double balloon device [SBP(158.38 ± 13.89)mmHg vs (162.48 ± 12.56)mmHg,P > 0.05,and SDP(112.71± 15.53) mmHg vs (108.19 ± 8.37) mmHg,P > 0.05].The rate of vaginal delivery was 89.2% (33/37),and the total hours of labor were (5.8 ± 0.63) h.Compared with selective cesarean section,vaginal delivery after double balloon to promote cervical mature had less blood loss (t =9.19,P <0.01),quicker postpartum recovery,shorter hospitalization time (t =11.18,P < 0.01),lower birth body mass (t =2.96,P <0.01) and higher scores of 1 minutes Apgar score (t =2.34,P <0.05).Conclusions The double balloon device appeared to be a safe and effective method to induce labor in women with preeclampsia and eclampsia.Wide scale studies and further use of the device for labor induction in women with preeclampsia and eclampsia were warranted.