Objective To observe clinical efficacy of Changyunning granula in treatment ofulcerative colitis.Methods 90 cases from March 2014 to August 2015 were randomly divided into observation group and control group of 45 patients in control group received conventional Western medicine treatment, observation group received more Granule intestinal treatment, patients were followed up and recorded Ig and C3 change the situation serum TNF-αand IL-8 changes, colonoscopy curative effect.Results The study group patients IgA, IgG, IgM, C3, respectively (3.65 ±0.48,13.41 ±2.36, 1.98 ±0.39,1.15 ±0.32)g/L, were better than control group (3.78 ±0.39,15.69 ±2.41, 2.45 ±0.36,1.63 ±0.29) g/L, and the difference was statistically significant (P<0.05).After observation group patients serum TNF-αand IL-8 were (26.9 ±6.9,12.5 ±3.8) ng/L, than control group (37.5 ±7.4,27.3 ±6.8)ng/L, and the difference was significant (P<0.05).Clinical observation group after treatment colonoscopy was 93.30%, better than control group, 68.89%, and the difference was statistically significant (P<0.05).Conclusion The clinical effect of intestinal Granule more precise treatment of ulcerative colitis, compared with conventional Western medicine has no significant side effects, it is worthy of further research and application.

Objective Beijing plans to run a DRGs-PPS pilot.Cost estimation of each DRG group needs a set of scientific reasonable standards for inpatient charge category.MethodsResource consumption accounting Classify charge item by practitioners,services,resources; medical consumables are singled out to emphasize the value of medical personnel's services; some of old categories are subdivided in order to be compatible with new categories.Results 19 old charge categories of patient discharge chart turn to 31 new items by dividing medical service into treatment,surgery,nursing,imaging,examination,management,paramedic,pharmacy,etc.ConclusionRegulating the charge categories of services,medical data is more consistent by using the same statistical coverage.Also it accurately present the incoming of all operationstreatment,surgery,nursing,imaging,examination,management,paramedic,pharmacy,etc.It gives government directions of decision-making to adjust the weight of DRG groups.

AIM: To improve the quality standard of Compound Xilingjiedu Tablets(Flos Lonicerae, Fructus Forsythiae, etc.). METHODS: Fructus Forsythiae、Fructus Arctii and Radix Glycyrrhizae were identified by TLC. The chlorogenic acid content of Flos Lonicerae was determined by HPLC. RESULTS: TLC spot developed were fairly clear. The method of content determination of chlorogenic acid by HPLC was practicable. CONCLUSION: The method is able to control the quality of products effectively.

OBJECTIVE:To investigate the anti-apoptosis effect and the mechanism of GM 1 ganglioside on nerve cell af?ter the spinal cord injury.METHODS:The rats with compressed injury at the T8.9level of spinal cord were employed as the model.Then the rats were divided into two groups at random,one for the control and one for GMI treatment.The rats in each group were administrated normal saline solution(20?l)and GM 1 (30?g,20?l)intrathecally10minutes after injury,respective?ly.The apoptosis of nerve cells in the injured spinal cord were examined by TUNEL and flow cytometry with nerve cells labeled with Annexin V/PI;and Caspase3activity was measured by fluorometric immunosorbent enzyme assay.RESULTS:The apoptotic cells appeared in both groups at4h and reached their peak on3rd day after the injury.The proportion of apoptotic cells and the intracelluar Caspase3activity in the GM 1 treated group were significant lower than those in the control group(P