In-stent restenosis after interventional treatment remains an unsolved and important clinical problem. The proliferation and migration of arterial smooth muscle cells are key events frequently followed by vascular restenosis after angioplasty and continuous inflammation may also be the other important factor for the restenosis after stenting. Study of the pathogenesis of restenosis may find some potentially novel therapeutic pathways for attenuating in-stent restenosis.

Objective:To solve the management problems of using mobile cart, PDA, flat-panel computer and other mobile devices in hospital, promote the evolution of mobile device management to intelligent management. Methods: Select the mobile device management system for hospital use based on their own characteristics.Results: Manage all the mainstream operating system and terminal equipment; manage the hardware and software of mobile terminal and assets in hospital.Conclusion: Improve the management, reduce the maintenance workload, save the cost of operation and maintenance.

The international meeting of the 10th anniversary of the AADO, convoked from Oct.8 to Oct. 10 in 2002 in Shanghai, was sponsored by AADO and organized by the two orthopedics departments of Changhai Hospital and Ruijin Hospital, Shanghai. The supporters of this meeting were Stryker Pacific, Stryker Trauma and Stryker China. There were 180 conventioneers who came from all over the mainland China, America, Germany, India, Japan, Hong Kong and Taiwan. They were clinical specialists in traumatology, managers from traffic departments and experts in vehicle design. 17 theses were selected for the meeting. The theme of the meeting was musculoskeletal trauma in developing countries with focus on road traffic injuries &geriatric fall injuries. Many experts in orthopedic trauma were invited to give presentations at the meeting on the theme.

Objective To evaluate the diagnosing and typing value of ultrasonography in adult congenital ureter cysts.Methods Ultrasonography findings were depicted of 29 cases with adult congenital ureter cysts confirmed by surgical and pathological examinations. Results In 29 cases of congenital ureter cyst, 14 occurred in right lateral, 12 in left lateral, and 3 in bilateral, totally being 32 cysts. The largest size of the cyst in diameter was (5.2) cm, and the smallest was (0.4) cm. Twenty-eight cases was diagnosed correctly by ultrasonography,in which the accuracy was (96.6)%(28/29). According to the sonographic patterns of size, shape, periodical change,1 case hydronephrosis, surgical and pathological results, 32 adult ureter cysts were divided into four types: type Ⅰ, papillary(12); type Ⅱ, round or ellipse(9);type Ⅲ, semilunar(4);and type Ⅳ, oblate(7). Conclusions Ultrasonographic appearance of adult ureter cyst is specific, and ultrasonography is of great value.

Objective To investigate the expression of E-cadherin(E-cad)and the relationship with the Lauren classification,the degree of histological differentiation,the clinical stage,the depth of invasion,lymph node metastasis and distant metastasis of gastric cancer. Methods 80 cases architecture of gastric cancer and normal tissue were collected.The expression level of E-cad in 80 cases of gastric carcinomas and their metastatic lymph node tissues were examined by immunohistochemical assays.Results The expression rate of E-cad in 80 cases of gastric carcinomas Was 55.00%.The expression level of E-cad was positively correlated with the Lauren classification,the degree of histological differentiation,the clinical stage,the depth of invasion,lymph node metastasis and distant metastasis(P＜0.05),but Was not correlated to patients sex,age and tumor size.The expression rates of E-cad in metastatic gastric carcinoma of primary lesions and lymph nodes metastasis were 35.48%and 32.26%. respectively. Furthermore, E-cad expression in metastatic gastric carcinoma was significandy correlated with primary lesions and lymph node memstasis(r=0.4978,P＜0.05).Conclusion The expression level of E-cad in gastric carcinoma Was closely correlated with the degree of tumor differentiation,infiltration and transferring.

[Objective]To observe the clinical effect of the treatment with Acupuncture Baihui and Acupoint Injection of Baihui with the injection of Herba Erigerontis on the post cerebral infarction depression(PCID).[Methods] 260 PCID patients were randomly divided into 3 groups.The first group was the amitriptyline group (80 cases),the treatment with the basis of service on the cerebral infarction and plus oral amitriptyline.The second group was acupuncture group (80 cases),treated with the basis of service on the cerebral infarction and plus acupuncture Baihui treatment.The third group was acupuncture and acupoint injection group (100 cases),the treatment with the basis of service on the cerebral infarction and plus acupuncture and acupoint injection of Baihui with the injection of Herba Erigerontis.Observe the changes of HAMD,SDS,MeSSS,MMSE,Barthel Index (BI) score of 3 groups before and after treatment for 4 w,8 w,and assess the efficacy of the treatment.[Results] After treatment,HAMD,SDS,MeSSS,MMSE,Barthel Index (BI) score were significantly improved in 3 groups,among them,the acupuncture group and amitriptyline group were improved similar on the observation score,acupuncture and acupoint injection group was significantly better than acupuncture group and amitriptyline.[Conclusion] Initial examinations show that it can significantly relieve the symptoms of PCID depression by Baihui,and worthy of clinical application.

BACKGROUND:Non-hematopoietic cell of mesenchymal stem cells (MSCs) or mesenchymal progenitor cells can differentiate into bone,cartilage,muscle,tendon,fat and bone marrow matrix in vivo and in vitro,thus becoming very valuable seed cells source in the field of tissue engineering.OBJECTIVE:To construct the tissue engineered tendon withⅠcollagen-polyglycolic acid as a scaffold and bone marrow MSCs as seed cells,and to observe the effect of tissue engineered tendon on repairing achilles tendon defects. DESIGN,TIME AND SETTING:Randomized controlled animal experiment was performed in the Xiangya Medical College of Central South University in 2003.MATERIALS:Healthy adult rabbits,irrespective of genders,weighing 1.5-2.5 kg,were offered by Animal Center of Xiangya Medical College,Central South University. Polyglycolic acid were purchased from Shandong Weigao Group Kanglida Medical Products Co.,Ltd (KLD Medical).SD rats were sourced from Department of Experimental Animals,Central South University.METHODS:Rabbit bone marrow was extracted to harvest MSCs with centrrfugation and adherence method,then bone marrow MSCs were isolated and amplified. Tail tendon was extracted from SD rats and prepared into type Ⅰ collagen solution,which was mixed and suture cultured with polyglycolic acid to construct collagen-polyglycolic acid scaffold. Other bone marrow MSCs,which were not induced in vitro,were incubated on collagen-polyglycolic acid scaffold to construct tissue engineered rabbit tendon models,with those without cells serving as controls. Thirty rabbit angle skins were cut open to separate tendon and produce a 3-cm defect. Fifteen rats in the experiment group was repaired with tissue engineered tendon,which was previously prepared with autologous bone marrow MSCs,while fifteen rats in the control group was given Ⅰ collagen-polyglycolic acid scaffold.MAIN OUTCOME MEASURES:Effect of tissue engineered tendon on repairing achilles tendon defects in rabbit.RESULTS:No matter whether contains autologous bone marrow MSCs,type I collagen-polyglycolic acid scaffold transplanted into animals exhibited column gel shape by general observation. At 4 weeks following transplantation,cordlike tissues were seen in the transplantation site,polyglycolic acid suture was degraded. At 8 weeks,the tissue engineered tendon tissues were cordlike shaped,white,lustrous and dense. They were well connected with receptor tendon tissues in the experiment group,without adhesion to peripheral tissues. In the control group,the tissues were slender and adhered to peripheral tissues. CONCLUSION:Using typeⅠ collagen-polyglycolic acid as a scaffold and bone marrow MSCs as seed cells,tissue engineered tendon can dramatically promote the repair of achilles tendon defects.

Objective To explore the effect of cilazapril on motor and cognitive function in hypertension with brain stroke. Method 42 hypertensive patients with stroke were divided into cilazapril treatment group(22 cases) and traditi onal treatment group (20 cases). The cilazapril group was treated with Inhibace 2.5 mg～5 mg daily. The traditional group was treated with nifedipine and/or di uretic. The blood pressure was measured twice a day during the treatment course. The activity of daily living (ADL), motor and cognitive function were assessed with Barthel index, Fugl-Meyer and MMSE assessment respectively before and 6 we eks after treatment. Results There were no difference between the two groups on blood pressure effectiveness, but blood pressure was more stable in the cilazapril gro up. Improvement of ADL and lower limb motor function in cilazapril treatment gro up were improved significantly than those of traditional treatment group(P<0.05). Although there was no difference between the two groups in the total value of cognitive function assessment, but the directional ability and memory function in group wa s higher than those in traditional group (P<0.05). Conclusion Cilazapril can decrease blood pressure steadily and can improve the activity of daily living and cognitive function in stroke patients.

Objective To investigate the effect of goserelin combined with marvelon in treatment of en -dometriosis(EM)and its effect on estrogen levels .Methods 120 EM patients were randomly divided into the ob-servation group(60 cases)and the control group(60 cases)according to the digital table.Two groups underwent laparoscopy .3.6 mg sustained release goserelin was injected subcutaneously from the anterior abdominal wall once every four weeks on the first time of menses recovery .The treatment continued during the following six months.The observation group were treated with marvelon on the basis of this , 1 tablet each day, 21 days of con-tinuous treatment and then began to take medicine on the 5 th day of the next menstruation during the following six months.The two groups were followed up for two years .The level of luteinizing hormone(LH), follicle-stimula-ting hormone(FSH)and estradiol(E2), the cumulative pregnancy rate, recurrence rate and peri menopausal sta-tus of the two groups were observed before and after treatment .Results The total effective rate was 96.67%and 83.33%respectively for the observation group and the control group .The difference had statistical significance (P<0.05).The level of E2, FSH, and LH at 1 month, 3 months, 6 months after treatmnet was lower than that before treatment(P<0.05).The level of E2, FSH, LH of two groups had no statistical difference (P<0.05). The cumulative pregnancy rate of the observation group was higher than that of the control group while the recur -rence rate was lower than that of the control group ( P<0.05 ) .The perimenopausal symptom score ( Kupperman score)of the two groups had no significant difference (P>0.05).Conclusion Goserelin combined with marvel-on can effectively improve the effect of laparoscopic surgery in treatment of endometriosis , lower estrogen level , improve patients'pregnancy rate , and reduce the recurrence rate .