Objective To introduce the birth and development of model of end-stage liver disease(MELD) and evaluate its effect on liver transplantation(LT) as a new scoring system.Methods Literatures of MELD applied in LT were analyzed retrospectively.Results MELD scoring system was used for predicting the prognosis of patients with end-stage liver disease and the death risk of candidates on waiting LT extensively and the order of organ sharing was determined by its predicable results.Conclusion MELD has been had a successful initial implementation for predicting the short-term survival probability and mortality in patients with end-stage liver disease,and meeting the goal of providing a system of allocation that emphasizes the urgency of the candidate while diminishing the reliance on waiting time,which has been proven to be a powerful tool for auditing the liver allocation system.

The urinary continence mechanism in the fetal and neonatal periods is the foundation of the development of continence function in the lower urinary tract (LUT).At present,it is rarely reported what is the fetus and newborns' LUT continence,and the domestic reviews about these knowledge is blank.The authors searched all the research reports about LUT continence and its mechanism in the fetal and neonatal period both in the human and animals,and reviewed the urinary continence of the fetus and newborns at first time at home,to fill the domestic blank of this field.

Objective To study the diagnosis and therapy of recurrent cholelithiasis caused by peripapillary duodenal diverticulum.Methods The clinical data of 40 patients with repeated formation of bile duct stones caused by peripapillary duodenal diverticulum were retrospectively reviewed,and the data on surgical treatment were analyzed.Results All the patients underwent duodenal diverticulum operation and subtotal gastrectomy (Billroth Ⅱ).Twenty-one patients in addition underwent R-Y cholangiojejunostomy,14 patients and 5 patients underwent choledochotomy with T-tube drainage and duodenotomy with Oddi sphincterotomy,respectively.In forty patients,three patients presented temporarily biliary fistula,two patients lost touch,three-eighty fully recover from an illness in three years.Conclusion Recurrence of bile duct stones caused by peripapillary diverticulum may be cured by duodenal diverticulum operation combined with bile duct surgery,which is a feasible and efficacious treatment.

Objective To explore the status and perioperative management of liver transplantation in treatment of portal hypertension. Methods Clinical data of 56 patients with portal hypertension who underwent (orthotropic) liver transplantation (OLT) from February 2000 to April 2004 were studied retrospectively.(Incidence) of complications,and in-hospital mortality and survival rate were analyzed. Platelet count after OLT was measured and liver blood flow was monitored by Doppler. Results Among the 56 OLT patients, 6 cases(10.7%) underwent simultaneous splenectomy. Incidence of complications was 40.3%,and in-hospital mortality and 1-,2-,and 3- year survival rate after OLT were 12.5% and 87.46%,85.19% and 81.58% respectively. Platelet count reached a nadir at post-transplant day 3. Conclusions OLT is an (effective) method for radical treatment of portal hypertension. Perioperative management is of vital importance for success of the operation and patient′s prognosis.

Objective To observe the effect of supervised rehabilitation on functional recovery in hemiplegia patients after stroke.Methods 65 patients with acute stroke were divided into supervised rehabilitation group and no-supervised rehabilitation group. They were assessed with Ueda Test and Barthel Index before and after treatment. Results The scores of the Barthel Index in supervised rehabilitation group were significantly superior to those of the not supervised rehabilitation group (P <0.05), while the scores of Ueda Test between these two groups were not significantly different (P>0.05). Conclusion Supervised rehabilitation can improve the function recovery, especially in activities of daily living.

Objective To investigate changes in craniomaxillofacial soft and hard tissues following orthodontic treatment by MBT edgewise technique with fix appliance in patients with Angle classⅡdivisionⅠmalocclusion. Methods Fifty patients with Angle classⅡdivisionⅠmalocclusion were selected in this study. All patients were treated with MBT edgewise technique. Cephalometrics tracings were performed before treatment and after treatment. Cephalometrics measurements were statistically analysed by t-test. Results After the orthodontic treatment, the main changes were the reduction of maxillary and mandibular prominence and the increasement of the Pg′B′-FH and Pog-Pog′and upper-lower prominence as well. The appearance of uncovered teeth by their lips was obviously improved. The changes of soft issue profile are the increment of nasolabial angle and the changes among UL-U1, LL-L1 and the E-line. Conclusion Patients with Angle classⅡdivisionⅠmalocclusion have normal overjet and overbite, and also have a better appearance of soft tissue after the extraction treatment.

Objective To review and summerize effectiveness and method of the Boston's balloon dilation in cardiac achalasia. Methods The intensified guide wire was inserted into stomach through mouth cavity under TV controll. The Boston's balloon was inserted to the cardiac stricture through the guide wire and dilatated with 15% contrast medium with to a maximum diameter for five minutes and then the balloon was dilatated again for 3～5 minutes, all together for 3～4 times. The severe stricture must be pre dilatated with 20～25mm diameter balloon. Results The balloon insertion was technically successful in all 26 patients. The once succese of ballon dilation was achieved in 24 patients and twice in other 2. Follow up time was from 2 weeks to 31 months(mean 10.6 months). Recurrent stenosis had not occurred in all patients. Remission rate of dysphagia was 100%. Esophageal reflux occurred in 3 patients. Conclusions The Boston's balloon dilatation is simple and effective for treatment of cardiac achalasia. The method sometimes may replace surgical procedure.

Objective To study the embryotoxicity and teratogenicity of monocrotophos in mice.Methods Sixty pregnant Kunming mice were randomly divided into four groups,15 in each:three groups were exposed to the monocrotophos at the doses of 0.05,0.10 and 0.20 mg/kg,10 ml/kg through gavage,during the period of organ formation(from 7th day to 16th day),once a day and the control group to distilled water.The pregnant mice were weighted in day of 0,6,12,18,and 20,and were sacrificed on 20th day of pregnancy.The numbers of living,dead and absorbed fetus were counted,and the uterus and placenta were weighted.The deformity examination was conducted.Results The maternal body weight of exposure groups were lower than those of control group in 12,18 and 20 day of pregnancy.With the increased doses of monocrotophos,the weights of pregnant mice showed a downward trend.Compared with the control group,the rates of dead fetus and absorbed fetus increased significantly,and the rates of living fetus,the fetal body weight and body length,tail length and placental weight decreased significantly(P

Objective To assess the role of dynamic-enhanced MR angiography (MRA) by comparing with DSA and CT arterial portography (CTAP).Methods Sixteen patients with liver diseases (mainly HCC) were included in the study. All patients underwent dynamic MRI of the liver using SENSE, digital subtraction angiography (DSA) and CTAP within two-week. MRA was reconstructed from raw data. The arterial phase of the modified MRA was compared with DSA for the evaluation of hepatic arteries and the portal phase compared with CTAP. In dynamic MRI, a fixed dosage (20 ml) of contrast medium and scan timing were used. Results The main branches and variations of the hepatic arterial system were well displayed on the dynamic-enhanced MRA, although the distant intrahepatic branches were showed poorly. Portal veins on MRV were showed as well as or even superiorly to CTAP. In addition, the inferior vena cava (IVC) was well demonstrated on MRV in most cases. MRV revealed 1 vascular variation which was not found on DSA and CTAP.Conclusion The dynamic-enhanced MRA using SENSE was a effective modality in demonstrating the hepatic vascular system. It may be a first choice modality in preoperative evaluation of orthotopic liver transplantation.

Objective To investigate the characteristics of pulmonary infection and susceptible factors following orthotopic liver transplantation (OLT). Methods Clinical data of 128 patients who underwent OLT from Feb. 1999 to Dec. 2004 were studied retrospectively in order to analyze primary pathogens, infectious time and susceptible factors.Results Forty-eight ( 37.5 %) of 128 patients had pulmonary infections and 27 ( 56.3 %) of them developed within postoperative 7 days. Thirty-four ( 70.8 %) cases suffered from mixed infection and 6 ( 12.5 %) died in the hospital after OLT. The primary pathogenic germs included Pseudomonas aeruginosa, Acinetobacter baumannii/haenolyticus, Golden staphylococcus, Aspergilosis and so on.Conclusion Pulmonary infection can be caused by various pathogens and associated with patients' constitution, mechanical ventilation, immunosuppressive drugs and so on.