1.Personality in patients with body-dysmorphic disorder
Aiguo HUANG ; Jianguo CHEN ; Yongjian SHEN
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(4):314-316
Objective To study the similarities and differences of personality in patients with body-dysmorphic disorder(BDD),obsessive-compulsive disorder(OCD) and ordinary person.As well as to provide information for clinical therapy. Methods All BDD patients( n =29),OCD controls( n =30) and normal controls( n =30) completed Self Rating Scale of Body Image (SRSBI) and Minnesota Multiphasic Personality Inventory (MMPI). Results Ten clinical scales score of MMPI in BDD were found significant higher than normal controls which including hypochondriasis,depression,hysteria, psychopathic deviate, masculinity-femininity, paranoia,psychasthenia,schizophrenia,and social introversion.Four clinical scales[(68.18±8.70),(65.44±8.73),(61.39±9.37),(60.70±12.88)] were significant higher than OCD controls[(61.09±13.29),(58.82±10.26 ),(56.23±9.58),(50.03±12.63)] which including psychopathic deviate,psychasthenia,schiaophrenia and social introversion( P <0.05). But hysteria scale was significant lower than OCD controls( P <0.01). Conclusion BDD patients have abnormal personality which is more significant than OCD patients. Significant abnormal personality are likely the psychopathology of BDD from which the clinic symptom produced.
2.The application of CAN bus to automatic biochemistry analyzer
Lizhi CHENG ; Zhaolu FANG ; Jianguo SHEN
Chinese Medical Equipment Journal 1989;0(03):-
This paper introduces the design of automatic biochemistry analyzer based on CAN field bus. The hardware and software of a single network node and several problems are narrated. Some related flow charts and source codes are also given. The involvement of CAN bus in the design of automatic biochemistry analyzer enhances the efficiency and the degree of automatization.
3.Investigation of Microorganism Pollution in Central Air Condition System of Public Buildings in Hebei
Fengling HOU ; Zhixin SHEN ; Jianguo LI
Journal of Environment and Health 2007;0(12):-
0.05), but there is great difference in contamination degrees among different public buildings(P
5.To take advantage of tumor hospital resources for clinical epidemiological study
Haizhen CHEN ; Kang SHEN ; Xuming WU ; Liping YANG ; Jianguo CHEN
Chinese Journal of Medical Science Research Management 2013;26(5):封2-封4,360
The tumor hospital has its unique resources superiority.To collect and utilize the information from tumor patients,information from their diagnosis and treatment,and biological specimens,through clinical epidemiology methods and design,would facilitate the deep development in the management and research at tumor hospitals in the new circumstances.Nantong Tumor Hospital,a first rate 3A hospital,and also one of the earliest-run specialized tumor hospitals in prefecture-level cities,possesses own basis for clinical epidemiological research,medical follow-up,and application of biobanking.In this paper we report the specific work plan and work contents,including:to establish a hospital-based cancer registry system for serving clinical epidemiology; to set up a follow-up system for clinical cases with tumor,in order to assess the effect of factors on tumor treatment and to analyse their survival rates; to build a biobank of tumor cases with perfect epidemiological information and background,fitting in with the needs of the development of translational medicine.The bottleneck problems in the work are also discussed.
6.Influence of psychological intervention on visual acuity, quality of life and satisfaction degree of nurse- patient relationship in patients with cataract during perioperative period
Limin XIANG ; Jianguo SHEN ; Meijin HOU ; Huiyu CHEN
Chinese Journal of Practical Nursing 2012;28(11):66-67
ObjectiveTo investigate the influence of psychological intervention on visual acuity,quality of life and satisfaction degree of nurse-patient relationship in patients with cataract during perioperative period. Methods120 cases of cataract patients from September 2009 to March 2010 during perioperative period in our hospital were enrolled,and randomly divided into the experimental group and the control group with 60 cases in each group.The control group received routine nursing,the experimental group was given psychological intervention based upon routine nursing.The postoperative visual acuity,the quality of life and the satisfaction degree with nurse-patient relationship were compared between the two groups. ResultsThe postoperative visual acuity,quality of life and satisfaction degree with nurse-patient relationship were higher in the experimental group than those in the control group. ConclusionsThe psychological intervention for cataract patients can improve their visual acuity,quality of life and satisfaction degree with nurse-patient relationship,and it is worthy of wide application.
7.Expressions and significances of RUNX3 and CyclinD1 in pancreatic carcinoma
Zhichuan LIN ; Jianguo LI ; Chunnuan WU ; Hongwu SHEN ; Zongkai ZOU
Chinese Journal of Pancreatology 2011;11(4):272-274
Objective To investigate the expressions of RUNX3 and CyclinDl in pancreatic carcinoma and their significance. Methods Expressions of RUNX3, CyclinD1 in 47 cases with pancreatic carcinoma, 18 cases with cystadenoma of pancreas and 12 normal pancreas cases were detected by immunohistochemistry, and the relationship between their expressions and clinicopathological parameters was analyzed. Results The positive expression rates of RUNX3 in pancreatic carcinoma, cystadenoma of pancreas, normal pancreas cases were 57.4% (27/47), 94.4% (17/18), 100% (12/12); the positive expression rates of CyclinD1 in pancreatic carcinoma, cystadenoma of pancreas, normal pancreas cases were 72.3% (34/47), 44.4%(8/18), 8.3% (1/12). RUNX3 expression was not related to the age and sex, but it was negatively associated with clinical staging, lymph node metastasis, the differentiation degree (P <0.05 ). CyclinD1 expression was not related to the age and sex, but it was positively associated with clinical staging, lymph node metastasis, the differentiation degree (P <0.05 ). The expression of RUNX3 and CyclinD1 was negatively associated (r = - 0.375, P = 0.009). Conclusions The expression of RUNX3 is decreased in pancreatic carcinoma. The expression of CyclinD1 is increased in pancreatic carcinoma. They may play an important role in the carcinogenesis and progression of pancreatic carcinoma.
8.TCM diagnostic method flow reconstruction and optimized management in the mass injuries emergency previewing reception
Yingchao SHEN ; Jianguo LI ; Zhenlong XUE ; Lanying HUANG
International Journal of Traditional Chinese Medicine 2011;33(11):1009-1011
ObjectiveTo study the effect of TCM diagnostic method flow reconstruction and optimized management in the mass injuries emergency previewing reception.MethodsWorking mode of TCM optimized receiving and dispatching flow were established and enforced.Results27 batch of 216 cases were received by emergency previewing reception in 2009~2010.Compared to 2009,patient dispatching time was shorten by 3.0 min,area dispatching time was shorten by 2.9 min in average.Emergency treatment satisfaction was elevated from 65% to 95% and rescue successful rate was increased from 82.3% to 89.6%.ConclusionTCM diagnostic method flow reconstruction and optimized management improved the level of management of in the mass injuries emergency previewing reception and obtained better results.
9.Treatment of primary trigeminal neuralgia with radiofrequency thermocoagulation on semilunar ganglion
Suoliang WANG ; Xiaodong SHEN ; Hui WANG ; Jianguo Lü ; Zhonghua WANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2009;30(6):751-753
Objective To observe the clinical effects and complications of primary trigeminal neuralgia treatment with radiofrequency thermocoagulation on gasserian ganglion. Methods Under the guidance of C-arm or DSA and with Hartel method, we percutaneously punctured the oval foramen to gasserian ganglion and performed radiofrequency times. Results Pain was completed eliminated in 53 of the 56 patients, which was regarded as degree Ⅰ of clinical cure with the curativeness rate being 96.4%; 1 case was of degree Ⅱ; 1 case was of degree Ⅲ; 1 case had no effect. The rate of satisfactory effectiveness was 96.4% and the total rate of efficacy was 98.2%. No severe complications were observed. Conclusion Radiofrequency thermocoagulation is a safe and effective method to treat primary trigeminal neuralgia with few severe complications.
10.Research Progress of Trastuzumab in the Treatment of HER-2 Positive Breast Cancer
Wenlong LIANG ; Lin LIU ; Xi CHEN ; Bin SHEN ; Jianguo ZHANG
Progress in Modern Biomedicine 2017;17(27):5385-5388
Breast cancer is one of the most common malignancies happened in female patients.The incidence of breast cancer in Chinese females has increased in recently years.Human epidermal growth factor receptor-2 (HER-2) exhibits gene amplification or high expression of receptor protein in about one third of breast cancer patients.HER-2 positive breast cancer patients has poor prognosis,high risk of recurrence and short survival.Trastuzumab is a specific inhibitor of human epidermal growth factor receptor-2 [1],which has been widely used in the treatment of HER-2-positive breast cancer patients,and trastuzumab molecular targeting therapy compared with the traditional chemotherapy,with the advantages of high specificity and low toxicity.It changes the natural disease progression of patients with HER-2-positive breast cancer and prolongs the patient's survival time.This article will review the researches on the four aspects,which including the development and the application of trastuzumab in the treatment of HER-2 positive breast cancer.