1.Personality in patients with body-dysmorphic disorder
Aiguo HUANG ; Jianguo CHEN ; Yongjian SHEN
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(4):314-316
Objective To study the similarities and differences of personality in patients with body-dysmorphic disorder(BDD),obsessive-compulsive disorder(OCD) and ordinary person.As well as to provide information for clinical therapy. Methods All BDD patients( n =29),OCD controls( n =30) and normal controls( n =30) completed Self Rating Scale of Body Image (SRSBI) and Minnesota Multiphasic Personality Inventory (MMPI). Results Ten clinical scales score of MMPI in BDD were found significant higher than normal controls which including hypochondriasis,depression,hysteria, psychopathic deviate, masculinity-femininity, paranoia,psychasthenia,schizophrenia,and social introversion.Four clinical scales[(68.18±8.70),(65.44±8.73),(61.39±9.37),(60.70±12.88)] were significant higher than OCD controls[(61.09±13.29),(58.82±10.26 ),(56.23±9.58),(50.03±12.63)] which including psychopathic deviate,psychasthenia,schiaophrenia and social introversion( P <0.05). But hysteria scale was significant lower than OCD controls( P <0.01). Conclusion BDD patients have abnormal personality which is more significant than OCD patients. Significant abnormal personality are likely the psychopathology of BDD from which the clinic symptom produced.
2.Investigation of Microorganism Pollution in Central Air Condition System of Public Buildings in Hebei
Fengling HOU ; Zhixin SHEN ; Jianguo LI
Journal of Environment and Health 2007;0(12):-
0.05), but there is great difference in contamination degrees among different public buildings(P
3.The application of CAN bus to automatic biochemistry analyzer
Lizhi CHENG ; Zhaolu FANG ; Jianguo SHEN
Chinese Medical Equipment Journal 1989;0(03):-
This paper introduces the design of automatic biochemistry analyzer based on CAN field bus. The hardware and software of a single network node and several problems are narrated. Some related flow charts and source codes are also given. The involvement of CAN bus in the design of automatic biochemistry analyzer enhances the efficiency and the degree of automatization.
5.Characteristics of neuropsychiatric impairment symptoms in patients with severe acute respiratory syndrome
Yamei TANG ; Yinyin ZHANG ; Jianguo LI ; Jun SHEN ; Yigang XING
Chinese Journal of Tissue Engineering Research 2005;9(24):208-209
BACKGROUND:Severe acute respiratory syndrome (SARS),an acute infection with a mutant coronavirus,is characterized by acute pulmonary inflammatory injury accompanied by possible multiple organ injuries. Besides somatic symptoms,affective disorder constitutes an obvious neuropsychiatric symptom in SARS patients.OBJECTIVE:To analyze the clinical features of SARS with neuropsychiatric involvement.DESIGN:A retrospective case analysis.SETTING:Department of Neurology,Department of Respiratory Diseases and Department of Radiology of Affiliated Hospital of Sun Yat-sen University.PARTICIPANTS:Totally 325 SARS patients treated in the Second Affiliated Hospital of Sun Yat-sen University and the 8th People's Hospital of Guangzhou from February 2003 to May 2003 were involved,including 173cases who developed neuropsychiatric symptoms.METHODS:The clinical data of 325 of SARS including 173 cases with neuropsychiatric symptoms were retrospectively analyzed.MAIN OUTCOME MEASURES:Clinical neuropsychiatric symptoms,ophthalmoscopic examination,and pathological findings in autopsy.RESULTS: ①The incidence of neuropsychiatric involvement was about 53.2% in SARS patients. The manifestations consisted mostly of headache (67.1%),dizziness(28.9%),conscious-ness disturbance(10.4%),mental disorder(4.6%), local orientational disorder(0.6%),seizures(1.2%),and affective disorders (30.6%);anxiety occurred in 20.2%,depression in 6.4%,suicidal tendency in 1.2%,and phobia in 7.5% of the patients with neuropsychiatric involvement. ②Among the 325 patients,56 were in critical condition of whom 47 had accompanying neuropsychiatric impairment,with significantly greater incidence than that in mild cases (P<0.01). ③Ophthalmoscopic examination performed in 4 patients showed blurred margin of the optic disc with retinal venous congestion. ④Autopsy in 2 cases identified edema of the perivascular tissue and vascular wall of the small veins with mononuclear cell and lymphocyte infiltration,neuron degeneration and demyelination in focal brain tissues.CONCLUSION:The manifestations of neuropsychiatric involement can vary in association with the severity of SARS,and the typical pathological changes include edema,neuronal demyelination etc.in the brain.
6.Effects of glucose-insulin-potassium on baroreflex sensitivity, left ventricular function and ventricular arrhythmia in the subacute phase of myocardial infarction in rats
Jianguo LIU ; He SHU ; Fuming SHEN ; Chaoyu MIAO ; Dingfeng SU
Academic Journal of Second Military Medical University 2004;25(4):433-433
Objective:Glucose-insulin-potassium(GIK) is clinically used for reducing mortality in acute myocardial infarction(MI). It is known that ventricular arrhythmia, left ventricular dysfunction and impaired baroreflex sensitivity(BRS) are the three major determinants for predicting the mortality after acute MI. The present work was designed to study the effects of GIK on BRS, ventricular arrhythmia, and left ventricular function in rats with coronary artery ligature. Sprague-Dawley rats were used and the myocardial infarction was produced by ligature of the left anterior descending artery. Five weeks after coronary artery ligation, BRS was measured in conscious state with a computerized blood pressure monitoring system and left ventricular function and electrocardiogram were determined in the anaesthetized state in the subacute phase of myocardial infarction. It was found that GIK did not affect the blood pressure and heart period in both conscious and anaesthetized rats. GIK did not enhance BRS, but reduced ventricular arrhythmia and improved left ventricular function by reducing left ventricular end diastolic pressure in anaesthetized rats with MI. It is proposed that reducing ventricular arrhythmia and improving left ventricular function contribute to the effect of GIK on reducing the mortality after MI.
7.TCM diagnostic method flow reconstruction and optimized management in the mass injuries emergency previewing reception
Yingchao SHEN ; Jianguo LI ; Zhenlong XUE ; Lanying HUANG
International Journal of Traditional Chinese Medicine 2011;33(11):1009-1011
ObjectiveTo study the effect of TCM diagnostic method flow reconstruction and optimized management in the mass injuries emergency previewing reception.MethodsWorking mode of TCM optimized receiving and dispatching flow were established and enforced.Results27 batch of 216 cases were received by emergency previewing reception in 2009~2010.Compared to 2009,patient dispatching time was shorten by 3.0 min,area dispatching time was shorten by 2.9 min in average.Emergency treatment satisfaction was elevated from 65% to 95% and rescue successful rate was increased from 82.3% to 89.6%.ConclusionTCM diagnostic method flow reconstruction and optimized management improved the level of management of in the mass injuries emergency previewing reception and obtained better results.
8.Expressions and significances of RUNX3 and CyclinD1 in pancreatic carcinoma
Zhichuan LIN ; Jianguo LI ; Chunnuan WU ; Hongwu SHEN ; Zongkai ZOU
Chinese Journal of Pancreatology 2011;11(4):272-274
Objective To investigate the expressions of RUNX3 and CyclinDl in pancreatic carcinoma and their significance. Methods Expressions of RUNX3, CyclinD1 in 47 cases with pancreatic carcinoma, 18 cases with cystadenoma of pancreas and 12 normal pancreas cases were detected by immunohistochemistry, and the relationship between their expressions and clinicopathological parameters was analyzed. Results The positive expression rates of RUNX3 in pancreatic carcinoma, cystadenoma of pancreas, normal pancreas cases were 57.4% (27/47), 94.4% (17/18), 100% (12/12); the positive expression rates of CyclinD1 in pancreatic carcinoma, cystadenoma of pancreas, normal pancreas cases were 72.3% (34/47), 44.4%(8/18), 8.3% (1/12). RUNX3 expression was not related to the age and sex, but it was negatively associated with clinical staging, lymph node metastasis, the differentiation degree (P <0.05 ). CyclinD1 expression was not related to the age and sex, but it was positively associated with clinical staging, lymph node metastasis, the differentiation degree (P <0.05 ). The expression of RUNX3 and CyclinD1 was negatively associated (r = - 0.375, P = 0.009). Conclusions The expression of RUNX3 is decreased in pancreatic carcinoma. The expression of CyclinD1 is increased in pancreatic carcinoma. They may play an important role in the carcinogenesis and progression of pancreatic carcinoma.
9.Effect of Intravenous Injection of Radix Astragali seu Hedysari on Acute Myocardiac Infarction in Anesthetized Dogs
Jianguo LIU ; Fengmian XU ; Weimin DU ; Fuming SHEN ; Dingfeng SU
Chinese Traditional Patent Medicine 1992;0(05):-
Objective:To investigate the protective effect of Intravenous Injection of Radix Astragali seu Hedysari on acute myocardiac infarction (AMI) in anesthetized dogs. Methods: Twenty health dogs were treated by ligating descending anterior of coronary with two-step method. The changes of electrocardiogram before and after ligation were recorded. After 4 hours myocardium were taken out and dyed with NBT to make sure of the extent of myocardiac infarction.Results: Intravenous Injection of Radix Astragali seu Hedysari could decrease the lethality of AMI, ameliorated ST changes on electrocardiogram induced by AMI, and reduced infarction area. Conclusions: Intravenous Injection of Radix Astragali seu Hedysari is effective in the treatment of AMI in anesthetized dogs.
10.Association of intuna-media thickness of common carotid artery with intercellular adhesion molecule-1 and C-reactive protein in type 2 diabetic patients
Shufang LU ; Jianguo SHEN ; Qiqian ZHU ; Lili GUAN
Chinese Journal of Endocrinology and Metabolism 1986;0(04):-
The intima-media thickness (IMT) of common carotid artery was measured using B-mode ultrasonography in 55 patients with type 2 diabetes mellitus (DM) and 25 normal controls. The serum levels of soluble intercellular adhesion molecule-1 ( sICAM-1) and high-sensitivity C-reactive protein ( hs-CRP) were measured by ELISA and high-sensitivity particle enhanced immunonephelometry respectively. The results suggest that sICAM-1 and hs-CRP were risk factors of thickened IMT in type 2 DM.