Objective To detect the expression of NF‐κB ,MCP‐1 in the endometrial carcinoma and their significance .Methods The expression of NF‐κB ,MCP‐1 in 52 cases of patients with endometrial carcinoma selected from January 2003 to December 2013 , and in 16 cases of endometrial atypical hyperplasia and 19 cases of proliferative endometrial were detected by immunohistochemistry assay .The relationship and correlation between clinical pathological characteristics was analyzed .Results The expressions of NF‐κB ,MCP‐1 proteins were significantly higher in the endometrial carcinoma than those of the endometrial atypical hyperplasia and proliferative endometrial (P<0 .05) .The expressions of NF‐κB and MCP‐1 were related with histological grade and myometrial in‐vasion (P<0 .05) ,but independent of clinical stage and lymph node metastasis (P>0 .05) .The expressions of these two proteins were positively correlated(r=0 .895 ,P<0 .05) .Conclusion NF‐κB ,MCP‐1 may participate in the progress of endometrial carcino‐ma .

To investigate the experience and efficacy of endoscopic thyroidectomy for papillary thyroid microcarcinoma (PTMC) through total areola approach.
 Methods: A total of 117 PTMC patients, who were diagnosed pathologically in Minimally Invasive Surgical Center, Second Xiangya Hospital, Central South University from June 2016 to December 2017, were divided into a endoscopic surgery group (n=72) and an open surgery group (n=45). The number of dissected central lymph nodes, blood loss, amount of drainage, occurrence of postoperative complication and recurrence were collected and compared.
 Results: Compared with the open surgery group, the blood loss was less and the operative time was longer in the endoscopic surgery group (P<0.05). There were no significant differences between the 2 groups in the number of dissected central lymph nodes, amount of drainage and occurrence of postoperative complication (all P>0.05). The mean follow-up time was more than 20 months, and there was no recurrence in the 2 groups. 
 Conclusion: Endoscopic thyroidectomy with central compartment neck dissection through total areola approach is safe and feasible in patients with PTMC. It has many advantages, such as no scar on neck, less blood loss, shorter hospital stay and more acceptable to young patients.
Carcinoma, Papillary ; surgery ; Endoscopy ; Humans ; Nipples ; Thyroid Neoplasms ; surgery ; Thyroidectomy