1.Clinical features and prognostic factors analysis of children with acute idiopathic myelitis
Chinese Journal of Applied Clinical Pediatrics 2014;29(19):1479-1482
Objective To study the clinical features and prognostic factors of children with acute idiopathic myelitis.Methods This study retrospectively collected and summarized 75 patients' clinical data who were diagnosed with acute idiopathic myelitis for the first time in Children's Hospital of Chongqing Medical University from Jan.2003 to Dec.2012.The relationship between clinical features and prognosis was analyzed by using SPSS 19.0 software.Results In this study,37 boys and 38 girls were inclued.The distribution of ages was bimodal.The incidence of the disease seemed to have two peaks.One was broader ranging between age 1 and age 4 and the second was between age 9 and age 13.The main symptoms of acute idiopathic myelitis were weakness,sensory loss and autonomic dysfunction.Among the 75 cases,all patients had different degrees of paralysis,59.0% (44 cases) of which had sensory abnormity and 80.0% (60 cases) had autonomic dysfunction.In addition,root pain (50.7 %,38/75 cases),bulbar paralysis (9.3 %,7/75 cases) and fever(66.7%,50/75 cases) also appeared in the process.Seventy cases had spinal magnetic resonance imaging(MRI) exams,in which 61 showed abnormal signal and T2-weighted hyperintensities could be found.Forty children were followed up successfully and 32 of which had a good outcome.Factors associated with poor outcome included spinal shock(P =0.001),the duration of spinal shock beyond 2 weeks (P =0.015),low score of maximal neurologic defect (9.25 ± 0.89 vs 14.03 ± 2.87,P =0.000),plateau period ≥ 12 days (P =0.004),the time to maximal defect ≤ 24 hours(P=0.029),fever in initial stage(P =0.029),and being female(P =0.021).Conclusions Acute idiopathic myelitis was mainly manifested by weakness.Autonomic dysfunction happened more commonly than sensory abnormity.Some patients suffered bulbar paralysis during the couse of the disease.Spinal MRI signal usually changed on T2-weight sequences.Meanwhile,identifying the factors associated with poor outcome as early as possible is beneficial to preliminary evaluation and active treatment.
2.Problems existed in the obsevation of illness process by low seniority nurses and their solving method
Chinese Journal of Practical Nursing 2008;24(12):9-10
Objective To approach the problems existed in the obsevation of illness process by low seniority nurses and their solving method. Methods The obversation ability for illness of 42 registered nurses who has worked within 3 years were evaluated.The contents included:Whether the observation was comprehensive,whether the physical checkup was correct,whether the nursing care was complete,whether the recognition of existing and potential nursing problems was in time and the mastering of important points of special medication. Results There existed common problems in the contents of illness observation,special nursing checkup,application and evaluaiton of nursing care and mastering of important points of special medication. Conclusion The illness observation ability of low seniority nurses needed improvement.Study of specialized knowledge is a premise and strengthened training is a pivotal tache.
4.Determination of Baicalin in Yanyan Capsules by HPLC
China Pharmacy 2007;0(36):-
OBJECTIVE:To establish an HPLC method for quantitative determination of baicalin in Yanyan capsules. METHODS:The determination was performed on Kromasil C18(250 mm?4.6 mm,5 ?m) with mobile phase consisted of meth-anol-water-phosphoric acid(47∶53∶0.2).The detection wavelength was set at 280 nm. RESULTS:The linear range of baicalin was 0.125~1.216 ?g(r=0.999 6) and its average recovery was 99.15%(RSD=0.62%,n=6).CONCLUSION:The method is simple and accurate,and it can be used for the quality control of Yanyan capsule.
5.IMMUNOHISTOLOGICAL FINDINGS IN HASHIMOTO THYROIDITIS AND SUBACUTE THYROIDITIS
Chinese Journal of Endocrinology and Metabolism 1986;0(03):-
A morphologic study was performed on the thyroid tissues of Hashimoto thy-roiditis (HT) and subacute thyroiditis (SAT) with histochemical and immunohistochemical methods. The results showed that the number and proportion of Ig and T positive cells were quite similar between these two diseases, suggesting that autoimmunoaction may play an important role in the generation and development of SAT.
6.Pregnancy within a cesarean delivery scar with placenta accreta in first trimester: diagnosis and conservative management with ultrasonography
Chinese Journal of Ultrasonography 2003;0(11):-
0.6. Conclusions Ultrasonography plays an important role in the diagnosis and conservative therapy of pregnancy within a cesarean delivery scar with placenta increta.
7.QUANTITATIVE DETERMINATION OF SODIUMDIPHACINONE IN ORGAN TISSUES BY SOLID-PHASE EXTRACTION AND DERIVATIVE SPECTROPHOTOMETRY
Chinese Journal of Forensic Medicine 1986;0(01):-
A comprehensive approach to the quantitative determination of sodium-diphacinone in human andrabbits organ tissues samples based on solid-phase extraction and derivative spectrophotometry hasbeen developed. This procedure, using acetonitrile to precipitate protein of tissues and GDX403(polymeric resine made in China) as absorbent in solid-phase extraction, was sufficientIy simple,rapid and cheaper. Results of this method was also reliable- Recoveries of sodium-diphacinone fromspiked tissues were around 70% at levels from 5 to 40pg/g. The detection limits of about 1 ?g/g forsodium-diphacinone could be achieved.
8.Component,Common Troubles and Solutions of MRI
Zhongquan JIANG ; Jingjiang TAN
Chinese Medical Equipment Journal 1989;0(02):-
The main composition of MRI system is introduced including magnet,gradient-RF system,cooling system,reconstruction system and operation system.According to the principle and functions of every component,the common troubles and the corresponding reasons of MRI system in using are analyzed,and the solutions are presented.[Chinese Medical Equipment Journal,2008,29(2):90,93]
9.Effect of cell apoptosis to peripheral blood mononuclear cells of patients with condyloma acuminatum
Chinese Journal of Immunology 1999;0(12):-
0.05).The rate of PBMC apoptosis with CA group was noticeably increased compared to that of normal control group(P
10.Retrospective Study of the Effect of Atorvastatin and Rosuvastatin at Different Doses on Liver Function in Patients with Coronary Heart Disease
Yu LIANG ; Jiyu TAN ; Mingyan JIANG
China Pharmacist 2016;19(3):521-523
Objective:To evaluate the impact of atorvastatin and rosuvastatin at different doses on liver function in the patients with coronary artery disease. Methods:A retrospective study was used, and the patients with coronary heart disease hospitalized in the first hospital of China medical university from January 2013 to March 2014 were selected. According to the drug variety and dosage, the patients were divided into four groups: A (atorvastatin, 20 mg·d-1), B (atorvastatin, 40 mg·d-1), C (rosuvastatin, 10 mg· d-1 ) and D ( rosuvastatin, 20 mg·d-1 ) . The basic information of patients, the indices of liver function( ALT,AST,ALP and TBIL) , the time of abnormal liver function, treatment strategies and prognosis were recorded. The incidence of abnormal liver function in the groups was compared, and the rationality and effectiveness of the intervetion strategies were evaluated. Results:A total of 269 patients were collected. Among them, 149 cases were with abnormal liver function in varying degrees, and 21 patients were with ALT>3?ULN. The incidence of ALT>3?ULN in atorvastatin high dose group was much higher than that in atorvastatin low dose group( P<0. 05). Conclusion:The patients treated with high dose atorvastatin (40 mg·d-1) have a high risk of liver injury.