Objective To approach the problems existed in the obsevation of illness process by low seniority nurses and their solving method. Methods The obversation ability for illness of 42 registered nurses who has worked within 3 years were evaluated.The contents included:Whether the observation was comprehensive,whether the physical checkup was correct,whether the nursing care was complete,whether the recognition of existing and potential nursing problems was in time and the mastering of important points of special medication. Results There existed common problems in the contents of illness observation,special nursing checkup,application and evaluaiton of nursing care and mastering of important points of special medication. Conclusion The illness observation ability of low seniority nurses needed improvement.Study of specialized knowledge is a premise and strengthened training is a pivotal tache.

Objective To study the clinical features and prognostic factors of children with acute idiopathic myelitis.Methods This study retrospectively collected and summarized 75 patients' clinical data who were diagnosed with acute idiopathic myelitis for the first time in Children's Hospital of Chongqing Medical University from Jan.2003 to Dec.2012.The relationship between clinical features and prognosis was analyzed by using SPSS 19.0 software.Results In this study,37 boys and 38 girls were inclued.The distribution of ages was bimodal.The incidence of the disease seemed to have two peaks.One was broader ranging between age 1 and age 4 and the second was between age 9 and age 13.The main symptoms of acute idiopathic myelitis were weakness,sensory loss and autonomic dysfunction.Among the 75 cases,all patients had different degrees of paralysis,59.0％ (44 cases) of which had sensory abnormity and 80.0％ (60 cases) had autonomic dysfunction.In addition,root pain (50.7 ％,38/75 cases),bulbar paralysis (9.3 ％,7/75 cases) and fever(66.7％,50/75 cases) also appeared in the process.Seventy cases had spinal magnetic resonance imaging(MRI) exams,in which 61 showed abnormal signal and T2-weighted hyperintensities could be found.Forty children were followed up successfully and 32 of which had a good outcome.Factors associated with poor outcome included spinal shock(P =0.001),the duration of spinal shock beyond 2 weeks (P =0.015),low score of maximal neurologic defect (9.25 ± 0.89 vs 14.03 ± 2.87,P =0.000),plateau period ≥ 12 days (P =0.004),the time to maximal defect ≤ 24 hours(P=0.029),fever in initial stage(P =0.029),and being female(P =0.021).Conclusions Acute idiopathic myelitis was mainly manifested by weakness.Autonomic dysfunction happened more commonly than sensory abnormity.Some patients suffered bulbar paralysis during the couse of the disease.Spinal MRI signal usually changed on T2-weight sequences.Meanwhile,identifying the factors associated with poor outcome as early as possible is beneficial to preliminary evaluation and active treatment.

A morphologic study was performed on the thyroid tissues of Hashimoto thy-roiditis (HT) and subacute thyroiditis (SAT) with histochemical and immunohistochemical methods. The results showed that the number and proportion of Ig and T positive cells were quite similar between these two diseases, suggesting that autoimmunoaction may play an important role in the generation and development of SAT.

OBJECTIVE:To establish an HPLC method for quantitative determination of baicalin in Yanyan capsules. METHODS:The determination was performed on Kromasil C18(250 mm?4.6 mm,5 ?m) with mobile phase consisted of meth-anol-water-phosphoric acid(47∶53∶0.2).The detection wavelength was set at 280 nm. RESULTS:The linear range of baicalin was 0.125～1.216 ?g(r=0.999 6) and its average recovery was 99.15%(RSD=0.62%,n=6).CONCLUSION:The method is simple and accurate,and it can be used for the quality control of Yanyan capsule.

0.05).The rate of PBMC apoptosis with CA group was noticeably increased compared to that of normal control group(P

0.6. Conclusions Ultrasonography plays an important role in the diagnosis and conservative therapy of pregnancy within a cesarean delivery scar with placenta increta.

A comprehensive approach to the quantitative determination of sodium-diphacinone in human andrabbits organ tissues samples based on solid-phase extraction and derivative spectrophotometry hasbeen developed. This procedure, using acetonitrile to precipitate protein of tissues and GDX403(polymeric resine made in China) as absorbent in solid-phase extraction, was sufficientIy simple,rapid and cheaper. Results of this method was also reliable- Recoveries of sodium-diphacinone fromspiked tissues were around 70% at levels from 5 to 40pg/g. The detection limits of about 1 ?g/g forsodium-diphacinone could be achieved.

The main composition of MRI system is introduced including magnet,gradient-RF system,cooling system,reconstruction system and operation system.According to the principle and functions of every component,the common troubles and the corresponding reasons of MRI system in using are analyzed,and the solutions are presented.[Chinese Medical Equipment Journal,2008,29(2):90,93]

The incidence of systemic fungal infections have increased dramatically, moreover, drug resistance including either primary (intrinsic) or secondary (acquired) resistance, becomes one of the main reasons accounting for the failure of treating invasive fungal infections in the past decades. Nowadays, clinically available antifungal drugs are limited and their combination in antifungal therapy was not effective. It is expected to be a new strategy to synergistically sensitize antifungal drugs against drug-resistant fungi by using new small molecules. Based on the study in our research group and the reported work of others, we reviewed the research of the natural products which have synergistic effect with the antifungal agents against drug-resistant fungi. This review focused on the resource, structure, pharmacological activity, and action mechanism of the compounds, as well as somewhat in common, and would provide theoretical base for seeking new drug against drug-resistance fungi.