Multiple tumor marker protein chip(C-12) quantitatively measures the level of twelve tumor marker proteins in human serum, therefore can assist the diagnosis of liver cancer, stomach cancer, colorectal cancer, pancreatic cancer and bile duct cancer. Compared with current diagnostic methods, C-12 is less time consuming, requires smaller samples, and still provides a wider detecting range and a higher accuray. C-12plays an important role in clinical dignosis of digestive system tumors.

Objective To analyze the results of gold labeled immunochromatographic assay (GICA ) ,enzyme-linked immunosor-bent assay (ELISA ) and time resolved fluoroimmunoassay (TRFIA ) detection for hepatitis B virus surface antigen (HBsAg ) . Methods GICA ,ELISA and TRFIA were employed to conduct the HBsAg testing in 11 058 specimens .Results The HBsAg posi-tive rates of GICA ,ELISA and TRFIA detection in 11 ,058 specimens were 15 .52% ,15 .64% and 15 .95% ,respectively ,with no statistically significant difference when pairwise comparison performed (P>0 .05) .In specimens which results of TRFIA quantita-tive detection was 0 .2- <2 .0 ng/mL ,the diagnostic compliance rates of GICA ,ELISA were 25 .0% and 75 .0% ,respectively .Con-clusion The diagnostic compliance rates of GICA ,ELISA detection in specimens with low concentration HBsAg are deceased .

OBJECTIVE: To study the equilibrium solubility of aesculin and its apparent oil/water partition coefficient,and to provide basis for absorption mechanism study.METHODS: Equilibrium solubility of aesculin at the pH of 1.2～8.0 was determined by saturation method.The apparent oil/water partition coefficients of aesculin were determined by shaking flask method.RESULTS: The equilibrium solubility of aesculin at the pH of 1.2～6.8 was fluctuated slightly;it increased rapidly at the pH of 7.4;the maximum equilibrium solubility of aesculin was obtained at the pH of 8.0(10.58 g?L-1).The oil/water partition coefficient of aesculin changed slowly at the pH of 1.2～6.0;it decreased significantly at the pH of 6.0;the minimum oil/water partition coefficient was obtained at the pH of 8.0(0.03).CONCLUSIONS: The equilibrium solubility of aesculin and its apparent oil/water partition coefficient are associated with the pH of medium.The reason that aesculin has no effect on uric acid after oral administration is relevant to poor gastrointestinal tract absorption ability.

OBJECTIVE:To study the pharmacokinetics of aclacinomycin A polylactide lyophilized nanopartical (ACM-A-PLA-NP) in plasma of rabbit.METHODS:HPLC was selected to determine the concentration of aclacinomycin A in plasma after a single dose of ACM-A-PLA-NP and lyophilized ACM-A.RESULTS:The pharmacokinetic parameters of these two dosage forms were obtained by 3p87.CONCLUSION:The lyophilized ACM-A-PLA-NP has a more sustained release character comparing with the lyophilized ACM-A.

Objective To explore the application effect of clinical nursing pathway on maintenance hemodialysis patients.Methods Totally 120 patients with maintenance hemodialysis between January 1 and December 31 2009 were randomly assigned to the control group and the observation group with 60 patients in each group.The clinical pathway was established and applied to the observation group.The treatment effect was compared between two groups.Results The incidence of complications and nursing errors declined with the application of clinical nursing pathway,and the doctor's orders compliance and the satisfaction and quality of care were improved significantly.Conelusions The application of clinical nursing pathway in maintenance hemodialysis patients is an effective method for improving overall care quality and the satisfaction degree of the patients with nursing,so as to improve their survival rate.

Objective: To make an impersonal evaluation on the effect of TCM on main biochemical indexes of non-alcoholic fatty liver disease (NAFLD),including ALT,AST,GGT,TC,TG,and HDL-C.Methods: We searched all the randomized controlled trials (RCTs) of TCM for NAFLD from CBM, CNKI,and VIP (1999-2008).RevMan4.2 was used in the analysis. Results: 11 RCTs,including 1078 patients,met the inclusion criteria.All of the trials were not adequate in methodological quality. None of them was double-blinded trial.The result of analysis showed that compared with basic Western medicine,TCM could increase the content of HDL-C,reduce the content of ALT,AST,GGT,TC and TG.Conclusion: The present meta-analysis suggested that TCM was beneficial over Western medicine for NAFLD which indexes including ALT,AST,GGT,TC,TG,and HDL-C.But we can not make a final conclusion due to low quality of RCT.

0.05). The ITA contains relatively higher content of elastin as compared with the others (P

Five resin casts of the coronary arteries and the hislological sections of three hesrts with the arteries injected Chinese ink were prepared in human adult autopsy subjec s . 3187 branches of the coronary arterial trees were counted and measured . By Strahler's system the branch pattern of the coronary arterial tree was described . According to the analysis of the geometrical morphology data, the relationships between the diameter , the length and the number of branches in each order and the branch order show the exponential function respectively , which have high correlation significance (p

0.05). ITA contains elastin a relatively higher than the other two (P

This paper reports the results of the study of 334 bifurcations in the coronary arterial trees of human adults and 245 dogs. The morphological features of the bifurcations ard measured by a microprojector and analysed with Murray's minimum energy principle. The results accord with the theoretical predictions based on the optimal principle, except a low percentage of errors.