1.Exercise therapy of Coronary Cardiopathy
Chinese Journal of Tissue Engineering Research 2001;5(5):7-9
This study discussed rehabilitation, definition staging (total three stage )of coronary cardiopathy (including acute cardiac in- farction ). Treatment principal, indication, contraindication, treating target and treatment scheme of every stage were also considered. Coronaryby pass and intracavity plastic operation should be performed according to the stated staging. Exercise therapy is the main part of rehabilitationscheme of coronary cardiopathy.
2.Exercise therapy for hypertension
Chinese Journal of Tissue Engineering Research 2001;5(5):6,21-
Exercise therapy is important in treatring hypertension by non-drug therapy. The mechanism, indications, contraindicationand excercise method and form were introduced in the study .
3.The exercise therapy of chronic congestive heart-failure
Chinese Journal of Tissue Engineering Research 2001;5(5):12-13,23
This study evaluated the exercise therapy of chronic congestive heart-failure(CHF) including response and function of exer- cise, the mechanism of improved cardiac function by exercise, evaluation of cardiac function, exercise testing, contraidication, indication andexercise prescription.
4.The advance of nutritional support in the critical ill
Jianan REN ; Jieshou LI ;
Parenteral & Enteral Nutrition 1997;0(03):-
The disadvantages of total parenteral nutrition (TPN) in critically ill patients were increased infection rate and hepatic dysfunction.Enteral nutrition (EN) can overcome the shortcomings of TPN and cost less.However,EN may not provide enough energy and protein because of the limited gut function.The best mode of the nutritional support in the critical ill patients is PN+EN.The non protein calorie and protein needs can be decided by the measured energy expenditure and overfeeding should be avoided.To further improve the critically ill patient nutritional status,immunonutrition and ecoimmunonutrition should be considered.
5.Characteristics and Implication of Post-Exercise Hypotension
Chinese Journal of Rehabilitation Theory and Practice 1997;3(3):118-122
Eighteen cases with post-exercise syncope or hypotenstion are reported in this paper. All subjects were middle-aged or elerly. The Characteristics include significant bradycardia or transient asystole, hypotension and dizziness or syncope,which occured 2 to 6 minutes after exercise and relieved a few minutes with supine position. Its occurence was related to exercise intensity and the capacity of cardiovascular regulation,but there was no any pathological evidence. The mechanism of this phenomenon remains nuclear.
6.Falls in Elderly and Balance and Gait Disorders (review)
Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):5-8
Fall is a common symptom in the elderly, which could be attributed to the interactions among the physiological, pathological,psychological factors of the older individuals and the environment with hazard factors. However, muscle weakness and balance and gait disorders have been identified as the most important etiology of falls. The intervention strategies should be developed individually and implemented based on the comprehensive assessment of the patient and the environment, to integrate exercise training as the main component for improving functional status. Tai Chi is a meaningful form of exercise which is effective in multi-perspective in preventing falls of the elderly.
7.Application of Rhythmic Cues in Rehabilitation of Gait Stability Disorders (review)
Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):9-11
One of the most common reasons why the elderly fall is gait stability disorders. Gait rhythm perturbations are presented in those diseases with stability disorders such as Parkinson's disease and stroke. Rhythmic cues with visual, auditory or somatosensory stimulation can promote walking stability caused by magnet effect, compensatory, relax and attention saving.
8.Traditional Chinese Medicine in Pain Management (review)
Chinese Journal of Rehabilitation Theory and Practice 2013;19(12):1140-1143
Traditional Chinese Medicine (TCM), especially acupuncture and herbal medicine, is mainly applicated in musculoskeletal diseases, gynaecopathia, functional gastrointestinal diseases and cancer related pain in recent decade over the world. The influence of TCM on quality of life of pain patients received more attention, but still lacked evidence-based basis. Recent years, the basic studies were focusing on the function researches and tried to find out the relationship between functional units with systems biology methods to explain the holistic concept of TCM. After searching the database during 2002 to 2012, this article reviewed the character, development and innovation of TCM applicated in pain management.
9.The effect of isometric contraction in opening femoral artery collateral circulation in rabbits
Liang HAN ; Jianan LI ; Binbin YU
Chinese Journal of Physical Medicine and Rehabilitation 2010;32(1):13-16
Objective To explore the effect of isometric contraction-induced ischemic burden for evoking maximal intrinsic femoral artery collateral circulation. Methods Twenty-four adult New Zealand rabbits weighing (2.0±0.5) kg were subjected to a model of isometric contraction-induced ischemia. An electrode was implanted in the sciatic nerve of the left hind limb for evoking isometric contraction of the gastrocnemius, which blocked local blood flow and induced local ischemia. Femoral artery collateral blood flow (FCBF) was measured using a micro-sphere technique. Results Local blood flow was the lowest at 40% of the maximal isometric contraction (IEmax), and reached plateau at 60% of IEmax. FCBF increased gradually and reached a plateau at 40% of IEmax in the 4th min. After 4 minutes at 40% of IEmax, FCBF had increased to higher than pre-stimulus, peaking in the 2nd minute, and then decreasing gradually to baseline at the 5th minute after reperfusion. It ceased to increase when reperfusion was prolonged to 8 or 10 min. Conclusions The minimal ischemic burden for full obstruction of the femoral artery is 40% of IEmax, and the shortest stimulus duration is 4 min. The maximal FCBF opening duration is no more than 5 min.
10.pMHC/scFv fusion protein mediates killing of tumor cells by viral specific cytotoxic T cells
Jianan LI ; Qian YU ; Xiongwen WU
Chinese Journal of Microbiology and Immunology 2011;31(2):162-167
Objective To study whether the HBC-A2/scFv fusion protein mediates killing of tumor cells by viral specific cytotoxic T cells. Methods The fusion protein was attached to the CD71-expressing, HLA class Ⅰ negative tumor cells. And then, cytolysis by viral peptide-specific CTLs which were generated by co-culture of peripheral blood lymphocytes from HLA-A2 positive donors with inactivated T2 cells pulsed with the viral peptide were tested by lactate dehydrogenase (LDH) releasing. Results The fusion protein can attach the active viral peptide/HLA-A2 complex to K562, HepG2 and U937 cells through binding of CD71 scFv to CD71 (37.30% ±8.25%, 27.20% ±3.88%, 21.80% ±6.49% ) and mediate cytotoxicity of viral peptide-specific CTLs against those cells in vitro ( K562: 42.08% ± 1.14% vs 8.07%± 1.39%; HepG2: 49.72% ± 1.59% vs 12.46% ± 1.26%; U937: 39.72% ± 3.26% vs 7.13% ±1.48% ). Conclusion This viral peptide/HLA-A2 complex targeted by CD71 scFv is able to redirect viral peptide-specific T-cell mediated immune responses against tumor cells.