2.Clinical effect observation of Dentium implant completed by once procedure
Jie GUO ; Jian DING ; Baodong ZHAO
Chinese Journal of Primary Medicine and Pharmacy 2016;23(13):1959-1962
Objective To observe and evaluate the clinical effect of Dentium planting system by once procedure.Methods A total of 45 patients who had 55 Dentium implants implanted were followed up for one year. Permanent restorations were finished 12 weeks after once procedure.Clinical effects were evaluated through clinical and imaging examination.Results Through the 55 Dentium implants of 45 patients,the success rate was 100%.All patients were satisfied with aesthetics and occlusal function.Conclusion Dentium implant completed by once procedure is safe and reliable with once procedure on clinical application.Both the survival rate and successful rate of implants were 100%.High degree of satisfaction from patients was achieved.Both bone tissue and soft tissue are well preserved.This system can obviously reduce bone resorption and improve aesthetic effect.
4.Design of method comparison study and bias estimation for albumin assays
Jian GUO ; Jiehong XIE ; Haijian ZHAO
Chinese Journal of Laboratory Medicine 2000;0(06):-
Objective It describes procedures for designing an analyzing a method comparison experiment for serum albumin(ALB) assay and determining the relative bias between two methods using split patient samples.Method According to the procedure described by the NCCL approved guideline: method comparison and bias estimation using patient samples; 40 patient samples were analyzed in 5 operating days, analyze each patient sample in duplicate using both BCG and BCP method. The duplicates were assessed for each method within the same run. The coefficient of correlation was calculated as well as the bia between the methods.Results In the patient′s serum sample, the bias between BCG and BCP methods were 1.8% at 50g/L or 5.5% at 40 g/L or 11.6% at 30 g/L for albumin. In the commercial quality control serum products, the bias between the two methods varied up to 36%.Conclusion In determination of the patient′s ALB, the bias between BCG and BCP goes up when the concentration of ALB is decreased. But the bias between the two methods varies up to 36% when the quality control serum is determined.
6.Study on radiation dose caused by 18F-FDG in PET/CT examination
Hai-min, ZHAO ; Jian-guo, ZHU ; Guo-ren, YANG
Chinese Journal of Nuclear Medicine 2008;28(5):347-349
Objective The aim of this study was to investigate the radiation dose caused by 18 F-fluorodeoxyglucose (FDG) in PET/CT examination and to optimize the concerned radiation protection. Methods Thirty patients from our conventional PET/CT examination were simple randomly selected, and they all underwent whole body PET/CT imaging. The radioactive dose of injected 18F-FDG was recorded. The internal radiation dose was calculated and the external radiation dose from patients was measured with the 451P-DE-SI ion chamber survey meter. The staff's dose was recorded with thermoluminescent detector (TLD). All dosimetry data were processed and analyzed statistically with Excel 2003. Results The injected radioactive dose of 18F-FDG was (432.9±51.8) MBq, and effective dose equivalent received per patient was (8.23±0.99) roSy. The correlation coefficient (r) of the dose equivalent rate and distance was-0.994 by power function curve fitting, and that of dose equivalent rate and time was - 0.988 by exponential curve fitting. The staff's dose was lower than the annual dose limit. Conclusions The patient's internal radiation dose caused by 18F-FDG in PET/CT examination is low, nonetheless, the clinician should always consider optimizing and minimizing the necessary radiation received by the patients. The patients having been injected with 18F-FDG should stay in one place to decrease their radiation to the public. From the medical point of view in optimizing radiation exposure, there may still be a potential to lower the injected 18F-FDG activity.
7.Progress on microRNA in aseptic loosening of prostheses.
Guo-Yin LIU ; Rui WANG ; Jian-Ning ZHAO
China Journal of Orthopaedics and Traumatology 2014;27(3):232-236
MicroRNA(miRNA) is a class of non-coding RNA that plays an important role in gene expression and controlling. In recent years,the role of miRNA in the development of the disease has aroused great interest. Abnormal osteoclastogenesis and persistent inflammatory response induced by wear particles or osteoblast differentiation and maturation is the main cause of aseptic loosening in joint replacements. New researches shows that persistent inflammatory response, osteoclastogenesis and osteoblast differentiation are closely associated with miRNA, suggesting that there are certain relations between miRNA and aseptic loosening of prostheses. Additionally, the alteration of the expression levels of some miRNA may be curative for aseptic loosening. With the findings of the new miRNA targets, the important role of miRNA is further confirmed.
Animals
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Arthroplasty, Replacement
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Cell Differentiation
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Humans
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Joint Diseases
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genetics
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metabolism
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surgery
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MicroRNAs
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genetics
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metabolism
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Osteoblasts
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cytology
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metabolism
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Prostheses and Implants
8.Application of combined detection of Golgi glycoprotein 73,phosphatidylinositol proteoglycan 3 and percentage of AFP heteroplasmon in diagnosis of primary hepatocellular carcinoma
Yingbin YE ; Xiuxiang HUANG ; Weigang GUO ; Jian ZHANG ; Dougui ZHAO
International Journal of Laboratory Medicine 2014;(16):2139-2141
Objective To study the application of the combined detection of Golgi glycoprotein 73(GP-73),phosphatidylinositol proteoglycan 3(GPC3 )and percentage of AFP heteroplasmon(AFP-L3%)in the diagnosis of primary hepatocellular carcinoma (PHC).Methods The concentrations of GP-73,GPC3 and AFP-L3 were detected by enzyme-linked immunosorbent assay(ELISA) in 154 patients with PHC(PHC group),78 patients with cirrhosis(cirrhosis group)and 56 healthy subjects(control group).Then the detection results were statistically analyzed.Results The levels of GP-73,GPC3 and AFP-L3% in the PHC group were signifi-cantly higher than those in the liver cirrhosis group and the control group(P <0.05).The positive rates of GP-73,GPC3 and AFP-L3% in the PHC group were 66.2%,72.1% and 53.2% respectively.The positive rate in the combined detection of these three in-dices could reach 97.9%,which was higher than the sensitivity and accuracy in any single index detection and the combination de-tection.In the PHC group,the comparison between different levels of GP-73 and AFP-L3% with the AFP levels showed the statis-tically significant difference(P <0.05 ).Conclusion The combination detection of GP-73,GPC3 and AFP-L3% can improve the sensitivity and accuracy for diagnosing PHC and has reference significance in the differential diagnosis of early PHC.
9.Progress in diffusion tensor imaging in the optic nerve disease
Peng-Bo, ZHAO ; Peng-De, GUO ; Jian, ZHOU
International Eye Science 2016;16(11):2036-2038
The optic nerve disease is a kind of diseases that seriously affect the visual function. In recent years, magnetic resonance diffusion tensor imaging ( DTI ) technology has been widely applied in the field of optic nerve diseases. Compared with the ophthalmic testing, such as optical coherence tomography imaging, visual evoked potential, field of vision, this method has obvious advantages. It not only can directly show the morphology changes of the optic nerve, visual pathway and visual cortex, but also can quantitatively analyze the morphological and pathological changes of the optic nerve, visual pathway and the visual cortex. This article reviews the imaging principle of diffusion tensor imaging, the progress and development prospect of diffusion tensor imaging in the study of the optic nerve diseases.
10.The complications of intravitreal triamsinolone acetonide injection in vitrectomy for proliferative diabetic retinopathy
Zhi-Yi, ZHAO ; Jian-Guo, SUN ; Yan-Yi, PENG
International Eye Science 2007;7(4):929-931
· AIM: To investigate the complications of intravitreal triamsinolone acetonide (TA) injection in vitrectomy for proliferative diabetic retinopathy (PDR).· METHODS: From February 2005 to January 2007, 18patients (18 eyes) with PDR who were injected with TA in vitrectomy were observed retrospectively after surgery.· RESULTS: During a postoperative follow-up period of 3 to 6 months (mean 4.6 months), some complications including deposit of TA granules on the macular region and surface of the retina (3 eyes), postoperative vitreous hemorrhage (3eyes), elevated intraocular pressure (2 eyes) and pseudohypopyon (1 eye)were observed.· CONCLUSION: The complications after surgery such as deposit of TA granules on the macular region and surface of the retina and pseudohypopyon could be cured without any special treatment. All eyes with elevated intraocular pressure after surgery were controlled by drug. Re-operation may be an effective method for patients with unabsorbable vitreous hemorrhage after vitrectomy.