1.Acute Ammonia Poisoning:Roentgenographic Features of Chest
Hongde HE ; Zhonghua LUO ; Jian XU
Journal of Practical Radiology 2000;0(12):-
Objective To study the X-ray signs of lung injury in acute ammonia poisoning.Methods The X-ray features of lung in ammonia poisoning in 37 cases were analysed and all patients were followed up for one year.Results The X-ray signs of lung in early of ammonia poisoning in 35 cases included increase of lung markings,lobular pneumonia,pulmonary interstitial emphysema and pneumonedema.In advanced stage in 15 cases,chronic bronchitis,pulmonary interstitial fibrosis and pulmonary bullae.Conclusion It's irreversible of injury that caused by acute ammonia poisoning in lung.
2.Diagnosis and Differential Diagnosis of the Intraosseous Well Differentiated Osteosarcoma
Siqing ZHOU ; Shan XU ; Jian XU ; Hongde HE
Journal of Practical Radiology 2000;0(12):-
Objective To investigate the clinical presentations,pathological features and radiographic appearance of intraosseous well differentiated osteosarcoma and its differential diagnosis.Methods One case of intraosseous well differentiated osteosarcoma was analyzed,and the clinical presentations,radiographic appearances and histological features of intraosseous well differentiated osteosarcoma were summaried on the basis of reviewing the related literatures.Results The age of onset of this disease was mostly within a range of 30~40 years.The scopes of this lesion were almost large,and the metaphyses of the long bone were the major targets of the lesions,especially the inferior extremity of femur and superior extremity of tibia.The tumor appeared as destruction of combined with bony restoration within the medullary cavity.The tumor was composed of fiber and bony tissue which had well differentiated cells with rarely nuclear division.About 50 % of patients was diagnosed incorrectly as benign lesion at first.Conclusion It is difficult to early diagnose intraosseous well differentiated osteosarcoma,but comprehending its pathological,immunohistological features and combining clinic will benefit for the correct diagnosis.
3.Some experience of field medical station equipment and materials management.
Shuang HE ; Chaoqun ZHANG ; Yonghe HU ; Longfu ZHOU ; Jian HE ; Kewei XU ; Ben XU
Chinese Journal of Medical Instrumentation 2013;37(6):454-456
The field medical station in military hospital plays an important role in the military logistic system. To better accomplish the duty of medical support mission, the problems of medical equipment and material store house management in the field medical station are discussed. Some targeted suggestions are introduced from daily management and the use of equipment respectively. It can be used as reference for other military hospitals to accomplish different medical support tasks.
Hospitals, Military
;
organization & administration
;
Military Medicine
;
instrumentation
5.X-ray Differential Diagnosis of Intra-thoracic Hodgkin’s Disease and Non-Hodgkin’s Lymphoma
Jian XU ; Xiuqin CHEN ; Zhonghua LUO ; Hongde HE
Journal of Practical Radiology 2001;0(09):-
Objective To investigate the X-ray characteristics and differential points of intra-thoracic malignant lymphoma-Hodgkin’s disease(HD) and Non-Hodgkin’s lymphoma(NHL).Methods The X-ray manifestations of intra-thoracic malignant lymphoma in 66 cases(including HD in 20 and NHL in 46) with complete clinical informations and pathologic results were retrospectively analysed.The lymphadenopathy of the hilar and mediastinum,the changes of the intra-lung and pleura were mainly observed and compared with the pathological results.Try to find the characteristic X-ray appearance of the HD and NHL.Results (1)48 cases had enlargement of lymph nodes of the hilar with/or mediastinum,and common seen in NHL,and the lymphopathy appeared as unilateral or asymmetry in NHL,bilateral or symmetry in HD.(2)The involvement of lymph nodes was mostly the anterior mediastinum and retrosternal in HD,the posterior mediastinum in NHL and to cause the paraspinal line widening.(3)Intra-pulmonary lesions always were interstitial changes and common seen in NHL,and seldom seen in HD.(4)NHL was often accompanied with pleural lesions,and HD not.Conclusion Both HD and NHL have its own X-ray characteristics .Carefully observing and analyzing these characteristics are helpful in diagnosing and differentiating HD and NHL.
6.Effect of Dimethyiformamide(DMF) on Histological Structure and Enzymes Activity in Testis of Mice
Yun-He ZHENG ; Lu HUANG ; Xu-Jian HOU ; Al ET ;
Journal of Environment and Health 2007;0(09):-
Objective To explore the effect of dimethylformamide(DMF)on the histological structure and enzymes activity in the testis of mice.Methods The KM male mice were treated with DMF by gavage at the doses of 0,0.5,1 and 2 g/kg respectively, once a day,for 30 consecutive days.On day 31,the mice blood samples were collected through eyes and then the mice were killed. Two mice were randomly selected in each group and one testicle was sampled to do the pathological examination,the other one for enzyme activity determination,including succinic acid dehydrogenase(SDH),lactate dehydrogenase(LDH)and acid phosphatase (ACP).Results Compared with the control group,all treated groups showed a significant decrease in body weight(P
7.Clinical application of feeding-artery embolization in treating massive hemoptysis
Jian XU ; Lijun SUN ; Hongde HE ; Jingbang LI ; Xuexin ZHANG
Journal of Interventional Radiology 2010;19(3):224-226
Objective To discuss the clinical application of feeding-artery embolization in treating massive hemoptysis.Methods The feeding-artery angiography was performed in 72 patients with massive hemoptysis.Based on the angiographic findings polyvinyl alcohol(PVA)or spring coil were selected as the embolization materials.The therapeutic results were retrospectively analyzed. Results Hemoptysis was completely controned almost immediately after the embolization procedure in 46 cases,while it was obviously alleviated in 13 cases.In 11 cases the hemoptysis disappeared completely after 2-4 times of embolization treatment,and in 2 cases surgery had to be employed.Conclusion Embolization of feeding-artery with PVA particles or spring coils is an effective and safe treatment for massive hemoptysis.The key point for decreasing reoccurrence is to occlude all feeding.arteries as far as possible.
8.Model establishment of adrenal gland self-implantation in greater omentum and its protection of transplanted liver
Shuxiong XU ; Zhaolin SUN ; Jian HE ; Jun LIU
Chinese Journal of Tissue Engineering Research 2007;0(18):-
BACKGROUND:The selective immunosuppression on transplanted organ was realized by local drug delivery system,which is one of efficient ways to avoid many kinds of side reactions induced by systemic drug delivery.By using the characteristics that adrenal gland can secret glucocorticoid,the adrenal gland or adrenal implant as the way of local drug delivery of glucocorticoid for transplanted organ is hopeful to avoid the complications induced by systemic and amount of use of glucocoticoid.OBJECTIVE:To establish a model of adrenal gland self-implantation in greater omentum,and to observe the protection of the adrenal gland implant on transplanted liver.DESIGN,TIME AND SETTING:This randomized controlled animal experiment was performed in the Experimental Animal Center of Guizhou Provincial People's Hospital from May 2007 to October 2008.MATERIALS:Fifty male Sprague Dawley rats were assigned as donors,and fifty male inbred strain Wistar rats were assigned as recipients.METHODS:After feeding one week,the recipient rats were randomly divided into two groups with 25 rats in each group.In liver transplantation after adrenal gland self-implantation in greater omentum group,allogenic liver transplantation was performed after successful model establishment of adrenal gland self-implantation in greater omentum.In simple liver transplantation group,only allogenic liver transplantation was performed.No immunosuppressant was used after transplantation in both of the two groups.MAIN OUTCOME MEASURES:The survival time of rats was observed.The morphology of the transplanted livers and the adrenal implants was observed at different time points.The activities of serum aspartate aminotransferase(AST),as well as the concentration of serum corticosteroid and total bilirubin were detected at different time points.RESULTS:The recipient adrenal implants recovered their endocrinal function at 7 weeks after adrenal gland self-implantation in greater omentum.After liver transplantation,histological examination showed that the adrenal implants survived well.The median survival time of rats in the liver transplantation after adrenal gland self-implantation in greater omentum group was more than 30 days,which is obviously longer than that(12 days) in the simple liver transplantation group.There was no significant difference in concentration of serum corticosteroid between the two groups.At 7 days after transplantation,activities of serum AST and concentration of total bilirubin of rats in the simple liver transplantation group were significantly higher than those in the liver transplantation after adrenal gland self-implantation in greater omentum group(P ≤ 0.05).In the liver transplantation after adrenal gland self-implantation in greater omentum group,pathological changes of transplanted livers showed as grade 0 according to Williams standard.In the simple liver transplantation group,a mild rejection appeared at 3 days after transplantation,and the pathological changes turned to severe and reached grade 3 according to Williams standard at 7 days.CONCLUSION:Adrenal implant which survives and recovers its endocrinal function after self-implantation in greater omentum has protection on the transplanted liver in early stage.
9.A Meta-analysis of the relationship between ACE gene L/D polymorphism and vitiligo
Danhua HE ; Jian XU ; Xingping ZHANG ; Zhiying CHEN
Journal of Chinese Physician 2017;19(4):538-541
Objective To investigate the relationship of angiotensin converting enzyme (ACE I/D) gene I/D polymorphism with vitiligo.Methods PubMed,the Cochrane Library,China academic journal full-text database and VIP database and Wan fang database were searched according to the inclusion and exclusion criteria,and the quality of included studies was assessed.The data were quantitatively analyzed by Stata 12.0 software.Results Nine articles were included.Meta analysis results showed that the susceptibility of vitiligo difference was statistically significant in the total population of ACE I/D genotype (DD + II)vs.DI (OR=0.759,95% CI:0.643 ~0.896,P=0.001),the (DD+DI) vs.II (OR=1.523,95% CI:1.153 ~2.011,P =0.003).The genotype subgroup analysis showed the D vs.I (OR =1.381,95% CI:1.054 ~1.810,P=0.019),DDvs.II (OR=1.830,95% CI:1.110~3.017,P=0.018),(DD+ II) vs.DI (OR=0.814,95% CI:0.667 ~0.994,P=0.043),and the (DD+ID) vs.II (OR=1.690,95% CI:1.147 ~2.489,P =0.008) in Asian.The difference was statistically significantly related to vitiligo.Arab genotype (DD + II) vs.DI (OR =0.545,95% CI:0.354 ~ 0.840,P =0.006) was associated with vitiligo occurrence.Begg's inspection publication bias analysis showed all genetic types did not exist any publication bias.Conclusions The ACE gene I/D polymorphism may be associated with vitiligo susceptibility.
10.Role of preoperative morphologic classification in solitary small hepatocellular carcinoma treated by RFA
Tie ZHOU ; Xu FU ; Jian HE ; Liang MAO ; Yudong QIU
International Journal of Surgery 2015;42(10):675-679,封3
Objective To invcstigate the value of preoperative imaging morphologic classification in solitary small hepatocellular carcinoma treated by RFA.Methods The clinical data of 73 patients with small hepatocellular carcinoma who rcccivcd radiofrequency ablation at the Affiliated Drum Tower Hospital of Medical School of Nanjing University from January 2008 to December 2012 were analyzed retrospectively.The lesions were classified into three types according to gross appearance in preoperative contrast-enhanced computed tomography (CT):single nodular type (type 1);single nodular with extranodular growth type or confluent multinodular type (type 2);infiltrating type (type 3).Thc clinicopathological features of patients with 3 types of tumors were compared by statistical methods.Patients were followed up via outpatient examination and telephone interview up to August 2014 or death.Results There were 24 cases of type 1,35 cases of type 2,14 cases of type 3,and the proportion were 20.2%,32.9%,47.9%,19.2%,respectively.The preoperative alpha-fetoprotein of type 3 was significantly higher than othcr types.The disease-free survival time of the three types were (37.2 ± 3.3) months,(20.9 ± 4.0) months,(14.4 ±4.9) months.The prognosis of the irregular types (type 2,type 3) is poor than the regular types (type 1).The overall survival time were (72.5 ± 4.7) months,(66.2 ± 7.3) months,(31.2 ± 5.3) months.The type 3 was the worst.The results of univariate analysis showed that morphologic classification,preoperative AFP,tumor size were related factors affecting the prognosis of patients (P < 0.05).The results of multivariate analysis showed that morphologic classification was the independent risk factors affecting the prognosis of patients (P < 0.05).Conclusion The preoperative imaging morphologic classification is the independent risk factors affecting the prognoses of patients with small HCC,which is help to choose the best treatment for patients with small hepatocellular.