Objective To study the clinical characters of coronary artery triple vessel lesion, and to provide a theoretical basis for the therapy to the disease. Methods The clinical data of 68 cases of coronary artery triple vessel lesion (group A) and 71 cases of coronary artery of single or double vessel lesion (group B) were analyzed retrospectively. Results The related risk factors (hypertension, hyperlipidemia, diabetes and smoking) and the clustering of these factors were not significantly different between the two groups (P>0.05). While the positive rate of the exercise stress test existed remarkable difference between the two groups(P<0.01).The extreme differences between the two groups existed also in the cases of building collateral circulation (P<0.001), and in LVEF and LVEDP (P<0.0001) demonstrated by left ventricular angiography. The majority of the coronary artery lesion in group A was on level Ⅳ, and much more lesions of level Ⅲ and level Ⅳ occurred in group A than in group B. Most patients in group A accepted the coronary intervention, while after operation the angina pectoris emerged in a high rate, then the rebuilding of coronary circulation had to be done. Conclusions The best treatment for the patients with coronary artery triple vessel lesion should be the operation of coronary artery bypass graft (CABG), if it's possible.

It has recently been demonstrated that Glycogen synthase kinase-3β (GSK-3β) plays an important role in tumorigenesis through its regulation of tumor cell growth via a variety of mechanisms. In some tumors, activation of GSK-3β inhibits the growth of tumor cells whereas in other tumors, GSK-3β promotes tumor cells growth, meanwhile, GSK-3β may also regulate sensitivity of chemotherapy drugs to tumor cells,thus GSK-3β is likely to become a novel target for tumor therapy.

The main content of TCM emotional therapy is according to the pathogenesis of abnormal emotional changes, such as functional disorder of viscera, qi and blood, corresponding therapeutic methods are formulated for the purpose of regulating mental state, eliminating emotional stimulating, restoring balance of viscera, qi and blood, and treating diseases in both body and mind. This paper outlined the emotional therapy in Chinese Medicine, demonstrated that TCM psychology has a long history, rich contents and variety of methods.

Depressed syndrome theory in Chinese Medicine originated from Huang Di Nei Jing and was developed and consummated by later doctors.Since the pathological changes and treatment of five essences depressed syndrome were ehcidated in Huang Di Nei Jing,doctors from successive generations had continuously been tmprovmg and ennclung the academic essential of depressed syndrome theory in Chinese Medicine,which made the theory more mature and flawless.All the theories,including Bing Wang'S improvement in the theory of treatment in five essences depressed syndrome,the first time Wuze Chen pointing out emotion leading to depressed syndrome,Qi-Blood-Flow-Smoothly theory raised by Congzheng zhang,the opinion of six depression by Zhenheng Zhu,the development on the theory of treatment in five essences depressed svndrome by Lv Wang,the posed of Abnomal-Rising-and-Failing-of-Vital-Energy by Sigong Dai,Lun Wang's version of relationship of Qi,Blood and phlegmatic stagnation,the idea from Xianke Zhao of all depressed syndrome belonging to liver disease,Yikui Sun'S talking about Qi itself in five viscera is depressive,and Shixiong Wang'S discussion about the most important character of Qi in body is flowing,gradually guided the research on depressed syndrome theory in Chinese Medicine moving forward.In this paper,the author emphasizes the development of depressed syndrome theory in Chinese Medicine.

Tissue factor (TF), a transmembrane glycoprotein with a molecular mass of 47000, plays an important role of coagulation within vessel wall. Recently, people also present that TF have identifying and regulating function in cells signaling. And it contributes in the pathogenesis of atherosclerosis, angiogenesis and restenosis. This review presents the development of TF in above mentioned .

Peroxisome proliferators-activated receptor-gamma(PPAR?),one of members of the nuclear hormone receptor superfamily of ligand-activated transcription factors,may affect the ocurrence and development of atherosclerosis(AS) through effective modulate lipocyte differentiation,improve glucose and lipoprotein decompensation and control inflammation reaction and so on.This review will focus on the recently development that relation on PPAR? and AS.

Humans ; Tympanoplasty

The EU is an international bridge of traditional Chinese medicine (TCM), and TCM in EU is of strategic importance. In this paper the progress on policies and regulations and approved products of herbal medical products in EU in 10 years were briefly reviewed, registration regulations were systematically, studied and some typical cases were analyzed. To provide reference for successful registration of TCM in EU and implementation of international strategy of TCM, five key elements (i. e. registration classification, approval procedure, approval authority, application product and application enterprise) to break through the registration barriers on TCM in EU were putted forwards correspondingly.
Drug Approval ; European Union ; Medicine, Chinese Traditional ; Policy ; Publications ; Social Control, Formal

Adolescent ; Antibody Formation ; drug effects ; Asthma ; drug therapy ; immunology ; Child ; Child, Preschool ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Powders ; Th1 Cells ; drug effects ; immunology ; Th2 Cells ; drug effects ; immunology

Adult ; Aged ; Face ; Female ; Humans ; Infection ; diagnosis ; therapy ; Male ; Middle Aged ; Neck ; Retrospective Studies