Objective To explore the effectiveness of TCM(Traditional Chinese Medicine)care on community patients with lumbar intervertebral disc protrusion(LIDP). Methods 80 patients with LIDP were randomly allocated to the control group and the experimental group with 40 in each one. Differentiated TCM care was applied to the experimental group, which included diet modification, environment adjustment,emotion conciliation, function improvement activities and massage. The control group was applied with routine care in community context. The treatment effect between the two groups was compared. Results The experimental group showed better consequences and life quality than the control group, the differences were statistically significant. The physical and functional condition was also better than the control group. Conclusions TCM care is applicable in community patients with LIDP, and it has significantly positive effects on rehabilitation and life quality of these patients.

Objective:To establish an HILIC-HPLC-ELSD method for the determination of allantoin in Rhizoma Dioscoreae. Methods:The separation was performed on a Waters XBridge HILIC column(150 mm × 4. 6 mm,5μm),the mobile phase was ace-tonitrile-water(85:15)with the flow rate of 0. 8 ml·min-1 ,and the nebulizer pressure was 40psi,the drifting tube temperature was 80℃ and the nebulizer temperature was 50℃. Results:The linearity of allantoin was good within the range of 1. 5-7. 5 μg( r =0. 998 1). The regress equation was Y=1. 67X+2. 35,the detection limit was 25 ng,and the average recovery of allantoin in Rhizoma Dioscoreae was 99. 9% with RSD of 0. 72%(n=9). Conclusion:The method is simple and reliable,which can be used in the deter-mination of allantoin in Rhizoma Dioscoreae.

Objective: To establish an HPLC method for the separation of optical isomers of palonosetron hydrochloride by RP-HPLC with HP-β-cyclodextrin ( HP-β-CD) as the chiral additive. Methods:The optimal separation process was performed on a Shi-seido CAPACELL PAK C18 VG 120 (250 mm × 4. 6 mm,5μm) column,the mobile phase was triethylamine (TEA) with HP-β-CD at different concentrations, the pH value was adjusted by acetic acid, the detection wavelength was 240nm, and the column temperature was 30℃. Results:The mobile phase was 0. 5% TEA (1% HP-β-CD, adjusting pH to 5. 5 with acetic acid)-acetonotirile (85∶15);the detection wavelength was 240nm, and the flow rate was 0. 5 ml·min-1 . The S, R-Isomer of palonosetron hydrochloride could be well separated. Conclusion:The method can be used as the optical isomer quality control for palonosetron hydrochloride.

Objective　To investigate the alteration and clinical significance of NK cell and T lymphocyte subpopulatien in patients with rectal carcinoma. Methods　 The numbers of NK cell and T lymphocyte in 26 healthy persons and 35 rectal carcinoma patients were detected by 3H-releasing method and FCM. Results　NK cell and CD3, CD4, CD4/CD8 were decreased significantly in patients with rectal carcinoma (P<0.05), which was positively correlated with Dukes staging (P<0.01), and was inereased after redical or palliative operation (P<0.05), but NK cell and CD3, CD4, CD4/CD8 were further decreased in patients with unresectable tumor after operation (P<0.05). Conclusions　The immunity of rectal patients was decreased with the development of the disease, and it will be improved after radical of palliative operation.

Objective To carry on the training of empathy ability among nursing undergraduates and understand its influence on that empathy and professional commitment. Methods Nursing undergraduates of two classes in the Chengdu University of TCM were selected as the objects in this study, who had accepted Nursing Psychology. The students in one class (52 cases) as the intervention group, while the students in the other class (61 cases )as the control group. Routine education was used in the control group, the empathy education was used in the intervention group in addition. On the basis of the Jefferson Scale of Empathy (JSE) and Nursing professional commitment Scale a survey on empathy ability among nursing undergraduates and professional commitment had done for the investigation of its influence on those two sides. Results After the training, the general professional commitment scores in the intervention group was 85.89 ± 11.86, which was significant higher than 77.53 ± 11.93 in the control group (t=3.822,P < 0.01). The final scores of commitment and empathy had significant relation with their respective latitudes (P < 0.05 or <0.01). Conclusions The training of empathy ability among nursing undergraduates affects their empathy ability and professional commitment. And students’professional commitment can be improved through some targeted trainings.

Objective To know about the reason of nursing students suffering workplace bullying. Method 25 interviewees were recruited by snowball sampling. The data were collected through the analysis of focus group interview. Results The interview data were analyzed by Colaizzi analysis method and three themes were extracted.They are the nursing students′own factors; organizational management factors;social and cultural factors. Conclusions According to the reasons for the nursing students suffered workplace bullying, formulating corresponding measures has an important role in improve the quality of clinical practice and the stability of nursing team.

Hepatocyte growth factor receptor c-Met and epithelial-mesenchymal transition (EMT) are closely related to the hepatocellular cancer.Recent researches have found that the mechanism of c-Met regulating EMT may play an important role in the carcinogenesis of hepatocellular cancer,which becomes a new research hot topic,Now we overviewed the progress on the mechanism of c-Met regulating EMT in hepatocellular cancer.

Objective To investigate the alteration and clinical significance of NK cell and T lymphocyte subpopulatien in patients with rectal carcinoma. Methods The numbers of NK cell and T lymphocyte in 26 healthy persons and 35 rectal carcinoma patients were detected by 3H releasing method and FCM. Results NK cell and CD3, CD4, CD4/CD8 were decreased significantly in patients with rectal carcinoma (P

Objective:To develop a novel method for the determination of the related substances in plerixafor. Methods: A re-versed-phase ion-paired HPLC method was applied in the qualitative and quantitative determination of plerixafor by an external standard method. The method was performed on a Waters Xbridge C18 column (250 mm × 4. 6 mm, 5 μm), the mobile phase consisted of 1-heptanesulfonic acid sodium salt buffer (pH 2. 0) and acetonitrile with the ratio of 80 ∶20 (v/v), the flow rate was 1. 0 ml·min-1, the detection wavelength was 210 nm, the column temperature was 35℃, and the injection volume was 10 μl. Results:The degrada-tion products were well separated from the main peak, the LOQ (limits of quantitative) of the related substance 1, 2 and 3 respectively was 21 ng, 35 ng and 26 ng with good linearity within respective linear range(r≥0.999 0) , the average recovery was 99.7%, 100. 3% and 101. 2%, and RSD was 1. 1%, 0. 8% and 1. 7%, respectively(n=9). Conclusion:The method is specific and accu-rate, which can be used for the quality control of plerixafor.

Objective To explore core competency of nursing students during internship in western China,and to provide reference for the nursing education.Methods 380 nursing students during internship were investigated with Competency Inventory for Registered Nurse (CIRN).Results The total score of core competency of nursing students was (136.40±31.99) points,weighted mean scores of eight dimensions was (2.36±0.51)points;the highest mean score was the dimension of legal and ethical practice (2.88±0.57)points,and the lowest mean score was the dimension of critical thinking (1.91±0.52)points.There was significant difference of core competency in students with different education background and with varied firstchoice profession.Conclusions The core competence of nursing students during internship remains at lower middle level.The nursing educators should shift their concept of nursing education to the new mode of professional competence orientation.