1.Treatment of unstable distal radial fractures with volar locking compression plate (LCP)
Jiagen SHENG ; Congfeng LUO ; Bingfang ZENG
Chinese Journal of Orthopaedic Trauma 2004;0(07):-
Objective To report and evaluate the treatment results of unstable distal radial fractures with volar locking compression plate (LCP). Methods 46 cases of unstable fractures of distal radius were treated with open reduction and LCP fixation through volar approach from April 2002 to May 2004. 14 of which underwent bone graft and 12 postoperative immobilization with plaster sprint. Results A follow-up of 6 to 30 (mean 21) months revealed bone union in all cases with a mean volar deviation angle of 9.7?and a mean ulna deviation of 21.3?of the distal radius. The wrist functions were evaluated by the modified Gartland and Werley system only to find 32 excellent cases, 11 good ones, 2 fair ones, and 1 poor one. Conclusions The unstable distal radial fractures can effectively be treated with open reduction and LCP fixation through volar approach. The subsidence of the radial articular surface can well be prevented and bone healing accelerated with supplementary bone graft.
2.Effects of exogenous basic fibroblast growth factor on in-sheathed tendon healing and adhesion
Jiagen SHENG ; Bingfang ZENG ; Peizhu JIANG ; Cunyi FAN
Chinese Journal of Tissue Engineering Research 2008;12(46):9177-9180
BACKGROUND: Basic flbroblast growth factor (bFGF) can promote tendon proliferation, collagen secretion,and out-sheathed tendon healing; however, effects on in-sheathed tendon are still unknown.OBJECTIVE: To explore the effects of exogenous bFGF on in-sheathed tendon healing and adhesion formation. DESIGN,TIME AND SETTING: A randomized controlled animal study, which was carried out in Experimental Animal Center, Shanghai Sixth People's Hospital from May 2004 to February 2005.MATERIALS: Ninety Leghorn chickens were randomly divided into 3 groups with 30 animals for each, and the right third digitorum longns tendon of the chicken was transected. METHODS: In the control group, the tendon was sutured in situ after transection. In the fibrin group,the tendon was sutured after 0.6 μL fibrin sealant (FS) was applied at repair site. In the bFGF group,the tendon was sutured after 0.6 μL FS mixed with 500 ng bFGF was applied at repair site. MAIN OUTCOME MEASURES: At 1,2,4 and 8 weeks postoperatively, the tendons of 6 chickens in each group were harvested for morphological and histological evaluation.Another six specimens of each group was obtained for biomechanical test at 8 weeks.RESULTS: There were no significant differences between control group and fibrin group. In bFGF group compared with control and fibrin groups, appearance of the angiogenesis,fibroblast proliferation and collagen production in the sheath, epitenon and parenchyrna at repair site occurred earlier and were more in quantity,the gliding excursion of the tendon was shorter, and the work of flexion and the ultimate tensile strength of the tendon were greater. CONCLUSION: The exogenous bFGF at tendon repair site can facilitate in-sheathed tendon healing, but also increase the tendon adhesion.
3.Application of reversed perforator-plus sural neurofasciocutaneous flap in lower leg
Nanji LU ; Yimin CHAI ; Chanyang WANG ; Peihua CAI ; Jiagen SHENG ; Binfang ZENG
Chinese Journal of Microsurgery 2009;32(3):181-183,illust 1
Objective To report the operative technique and clinical results of reversed perforator-plus sural neurofasciocutaneous flap in lower leg. Methods Perforator-plus sural neurofasciocutaneous flaps, which designed along the axis of the sural nerve and based on the dual-pedicle of fasciocutaneous and per-oneal perforator, were used to reconstruct soft-tissue defect in lower extremities. Results Twenfy-four flaps, ranged from 25 cm×12 cm - 8 cm ×7 cm in size, survived completely without venous congestion and distal ischemia and necrosis. The color and texture of the flaps were good. The appearance and functional re-suits were satisfactory with following up for 6 to 12 months. Conclusion The modified technique in pediclehave minimized the complication, enlarged the size of the flap and improved the survive rates. It is a goodmethod in repairing large soft-tissue defects of extremities.