Objective To evaluate the clinical outcome of reconstruction of traumatic digital arthritis by transfer of free proximal interphalangeal joint of the second toe with toe reserving technique.Methods The study enrolled nineteen patients with traumatic digital arthritis treated from May 2013 to April 2016.The patients consisted of fifteen males and four females,and mnean age was 27.3 years (range,18-52 years).Finger involved included index fingers in 10 patients,middle fingers in seven and ring fingers in two.The joint of digit was reconstructed by transplanting the proximal interphalangeal joint of the second toe with a monitoring flap,and bone defect of the second toe was repaired with autogenous iliac bone graft.Wound was closed directly in six patients and covered by island flap from the foot dorsurn in 13 patients.Evaluation indicators contained survival rate of the free joint and island flap,appearance and fracture healing of the finger and toe and mnotion of the proximal digital joint.Finger function was studied using the evaluation standard of upper limb function set up by hand surgery branch of Chinese Medical Association.Healing in the donor site,foot function and related complications were observed.Results All the free joint and island flap survived.Period of follow-up was 6-30 months (mean,14 months).The fractured finger healed at 2.5 months on average,and appearance of the finger was good.Flexion range of the proximal digital joint was 63 °-80° (mean,74°) and extension range was-20°--10° (mean,-14°).Finger function was excellent in eleven patients and good in eight patients,with the excellent-good rate of 100％.Hematoma of the dorsal region of the foot occurred in one patient and the cut healed well after taking out some stitches and drainage.All fractured toe healed at 2.6 months.Except that one patient had fracture malunion with minor outward inclination,all presented good appearance of the toe without influencing walking and running.On the part of iliac,there was only one inconspicuous linear scar without any discomfort.Conclusions Transfer of free proximal interphalangeal joint of the second toe with toe preservation restores the anatomy structure and function of the digital joint.Meantime,autogenous iliac bone grafting combined with island flap from the foot dorsum for coverage of donor site defect retains the toe length and reduces injury of the donor site.

Objective To evaluate the clinical outcome of the method of repairing donor site of foot after improved toe-to-thumb reconstruction utilizing superficial circumflex iliac artery perforator (SCIAP) chimeric flap.Methods Fourteen cases of thumb defect were recruited from April,2012 to January,2016.According to Gu Yudong's classification,5 cases met the criterion of type Ⅰ,4 cases met the criterion of type Ⅱ,and 5 cases met the criterion of type Ⅲ.For type Ⅰ,the thumb was reconstructed with the great toe wrap-around flap.For type Ⅱ and Ⅲ,the thumb was reconstructed by the combined tissue with mutual artery (great toe wrap-around flap,and the bonetendon tissue of the second toe).All the donor sites of foot were repaired utilizing SCIAP chimeric flap.Results All the reconstructed thumbs survived.Among 14 free flaps of donor site,1 case suffered venous crisis and survived after exploration and rescue surgery.Dorsal skin necrosis of the second toe was found in 1 case,which was healed by local skin flap transposition.All patients were followed-up ranged from 3 to 30 months (averaged at 16 months).In spite of slightly bloated,the color and texture of all the flaps' was satisfied,and the average healing time of the bone in the donor sites was 2.5 months.All patients did not feel painful and had no adverse effect when walking and running.Three months after the operation,5 slightly bloated flaps in the donor sites under went flap plastic and achieved better appearance.On the part of iliaca,there was only one inconspicuous linear scar without any discomfort.Conclusion Repairing donor site of foot after improved toe-to-thumb reconstruction utilizing SCIAP chimeric flap was an ideal method.Using this method,the reconstructed thumb can achieve good appearance and function,all the toes of donor site were reserved,and the disability of the donor site is minimized.

A patient recovered partial hand functions by 4 reconstructed digits based on a pair of complete defect hands that lost all of 10 digits on March, 2014. The thumbs were reconstructed with bipedal nail flaps combined with iliac bone, the right index finger and left middle finger were reconstructed with the 2nd toes of feet. Bilateral superficial circumflex iliac artery rerforator flaps (SCIPF) were taken to repair the donor areas of feet. According to the DASH-Chinese upper limb function score system, the function of both hands was obviously improved in six and a half years after surgery. The function of both feet was not significantly affected.

Objective To study the relationship between portal hypertension(PHT) and heme oxygenase-1(HO-1)mRNA expression in rats.Method An animal model of PHT induced by partial portal vein constriction was established to detect the expression of HO-1mRNA in the liver,spleen, and splenic vein of rats by situ hybridization method. Result HO-1mRNA was not detected in the liver, spleen, and splenic vein in the control group. In PHT rats, HO-1mRNA was not detected in the liver;but in the spleen,the expression of HO-1mRNA was 83.3%;in the splenic vein,the expression was 55.6%. Conclusions The PHT rat is in stress condition.The expression of HO-1mRNA in the spleen and splenic vein of PHT ratsare increased and the metabolic product of HO-1 may exacerbate the PHT.

Tissue expander is a device that induces tissue expansion and can be used to repair tissue defects. However, traditional dilators have the risk of exposure, skin infection, and poor blood flow in local tissue. Hydrogel is a kind of organic macromolecular polymer which can be expanded gradually by absorbing liquid and maintains a certain volume. The hydrogel expander can be applied to the tissue dilation. Compared with the traditional diilator, it can significantly reduce complications with better result. This review mainly summarizes the latest research progress of self-expanded hydrogel dilators in tissue expansion, and looks forward to its future application.

Tissue expander is a device that induces tissue expansion and can be used to repair tissue defects. However, traditional dilators have the risk of exposure, skin infection, and poor blood flow in local tissue. Hydrogel is a kind of organic macromolecular polymer which can be expanded gradually by absorbing liquid and maintains a certain volume. The hydrogel expander can be applied to the tissue dilation. Compared with the traditional diilator, it can significantly reduce complications with better result. This review mainly summarizes the latest research progress of self-expanded hydrogel dilators in tissue expansion, and looks forward to its future application.

Tissue expander is a device that induces tissue expansion and can be used to repair tissue defects. However, traditional dilators have the risk of exposure, skin infection, and poor blood flow in local tissue. Hydrogel is a kind of organic macromolecular polymer which can be expanded gradually by absorbing liquid and maintains a certain volume. The hydrogel expander can be applied to the tissue dilation. Compared with the traditional diilator, it can significantly reduce complications with better result. This review mainly summarizes the latest research progress of self-expanded hydrogel dilators in tissue expansion, and looks forward to its future application.

Tissue expander is a device that induces tissue expansion and can be used to repair tissue defects. However, traditional dilators have the risk of exposure, skin infection, and poor blood flow in local tissue. Hydrogel is a kind of organic macromolecular polymer which can be expanded gradually by absorbing liquid and maintains a certain volume. The hydrogel expander can be applied to the tissue dilation. Compared with the traditional diilator, it can significantly reduce complications with better result. This review mainly summarizes the latest research progress of self-expanded hydrogel dilators in tissue expansion, and looks forward to its future application.

An electrochemical L-lactate biosensor was fabricated by combining Platinum nanoparticles (Pt-nano) with multi-walled carbon nanotubes(MWCNTs).L-lactate oxidase(LOD) was immobilized on the surface of the glassy carbon electrode (GCE) modified with MWCNTs and Pt-nano.The surface of resulting LOD/MWCNTs/Pt-nano electrode was covered by a thin layer of sol-gel to avoid the loss of LOD and to improve the anti-interference ability.The cyclic voltammetric results indicated that MWCNTs/Pt-nano catalyst displayed a higher performance than MWCNTs.Under the optimized conditions, i.e., applied potential of 0.5 V, pH 6.4, 25 ℃, the proposed biosensor's determination range was 0.2-2.0 mmol/L, response time was within 5 s, and the sensitivity was 6.36 (A/(mmol/L).It still kept 90% activity after 4 weeks.The fabricated biosensor had practically good selectivity against interferences.The results for whole blood samples analyzed by the present biosensor showed a good agreement with those analyzed by spectrophotometric method.

31 patients with cysticercosis of cerebral ventricles verified by operation or pathological investigation were reported. All patients were between 7 and 64 years of age and 14 were females. All had a single cyst. Since 29 patients (94%) were without a history of intestinal taeniasis, it was proposed that most patients of cysticercosis of cerebral ventricles were caused by hetero-infection and the entrance of Cysticercus into brain ventricle was through choroid plexus along the cerebro-spinal fluid. This is probably the reason why it occurs mostly in the 4th ventricle. The clinical manifestation of cysticercosis of cerebral ventricles were paroxysmal headache and vomiting caused by increased intracranial pressure. Ventricu-lography and CT scanning have considerable diagnostic value. Removal of Cysticercus by surgical operation is successful (Figs. 1 - 8).