1.Clinical features of pulmonary hypertension associated with hyperthyroidism
Chinese Journal of Endocrinology and Metabolism 2014;30(2):133-134
Eighty-seven patients with hyperthyroidism were enrolled in a retrospective study,and 35.6% of them also suffered from pulmonary hypertension(PH).Advanced age and systolic or diastolic dysfunction of left heart were risk factors in the mechanism of PH associated with hyperthyroidism (all P<0.05).However,autoimmune disorder was found as a non-related factor in the mechanism of PH(P>0.05).
2.Comparative study of ultrasonographic diagnositic value of tubal pregnancy via transvaginal as compared with transabdominal approach
Chinese Journal of Radiology 2001;0(08):-
Objective To assess the value of ultrasoud examination with transvaginal scaning(TVS) in the diagnosis of tubal pregnancy(TP). Methods 40 cases of clinically suspected TP were exeamined by two ultrasoud approaches: transvaginal and transabdominal prior to surgery.Based on surgery and pathology ,the sonographic manefestutions and diagonostic results of both methods were compared and analized statisticlly. Results The TP masses were visualized in 36 cases in TVS group(36/40) as compared with 27 cases in TAS group (27/40) (? 2=7.364, P
5.Huguosi Hospital of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100036, China
Journal of Acupuncture and Tuina Science 2022;20(1):65-71
Objective: To observe the clinical efficacy of Tuina (Chinese therapeutic massage) plus Shen Ling Bai Zhu San for pediatric diarrhea due to spleen deficiency.Methods: A total of 105 children with diarrhea due to spleen deficiency were selected and randomized into two groups by the random number table method. Fifty-two cases in the control group were treated with oral Shen Ling Bai Zhu San, and 53 cases in the observation group were treated with additional Tuina treatment. The clinical efficacy was evaluated after treatment, and the changes of traditional Chinese medicine (TCM) symptom scores were observed. Results: During the trial, there were three dropouts in the observation group, and two in the control group. After the treatment, the total effective rate was 100.0% in the observation group, and 90.0% in the control group. The difference between the two groups was statistically significant (P<0.05). The scores of primary and secondary symptoms, and the total scores of TCM symptoms in both groups were significantly lower than those before treatment (P<0.05). And the scores of primary and secondary symptoms, and the total score of TCM symptoms in the observation group after treatment were lower than those in the control group (P<0.05). There were no obvious adverse reactions in either group during the treatment. Conclusion: Tuina plus Shen Ling Bai Zhu San has a better therapeutic effect in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone.
6.Clinical value of risk of ovarian malignancy algorithm in risk stratification of ovarian cancer
Aimin ZHANG ; Li JIA ; Peng ZHANG
Chinese Journal of General Practitioners 2014;13(7):580-582
The serum specimens were collected from ovarian cancer (n =100),benign ovarian disease (n =69) and healthy women (n =95).The serum levels of HE4 and CA125 were detected.Risk of ovarian maliqnancy algorithm (ROMA) was calculated.Accuracy of prediction was evaluated by the area under receiver operating characteristic curve (ROC-AUC).And validity of prediction was evaluated by sensitivity and specificity.The results showed that the median level of ROMA algorithm was 83.0%,8.9% and 8.7% in ovarian cancer,benign ovarian disease and healthy women groups respectively.The difference were statistically significant (all P < 0.01).Compared with benign ovarian disease group,the ROC-AUC of ROMA algorithm was 0.900 in ovarian cancer group.The sensitivity and specificity were 81.0% and 92.8% in ovarian cancer group respectively.Thus ROMA algorithm is a useful parameter in risk stratification for ovarian cancer.The diagnostic accuracy of ROMA algorithm is better than that of HE4 and CA125 in ovarian cancer.
7.Summary and analysis of internet-based infectious diseases image materials
Shujun ZHANG ; Fujie LI ; Jia CAI ; Bei JIA ; Wenxiang HUANG
Chinese Journal of Medical Education Research 2015;14(4):408-411
This paper summarizes the features of web sites that would be useful to infectious diseases physicians by exploring the Internet through search engine including Google,Baidu and Yahoo.Meanwhile,suggestions from professional forums,web sites and publications are also taken into consideration.Nine Comprehensive sites containing three categories and more of microbial pathogens,nine special sites for parasites,four special sites for fungi,two special sites for viruses and two special sites for bacteria are collected.Subjective navigation for each site is given.Features of these sites,including laboratory images,clinical images and number of images are also described.
8.Clinical observation on eyelid herpes zoster with external use ganciclovir ophthalmic gel
Shu-Quan, LI ; Jia, JIA ; Zhi-Yong, ZHANG
International Eye Science 2014;(7):1356-1357
AlM: To observe the treatment efficacy of eyelid herpeszoster with external use ganciclovir ophthalmic gel.METHODS:A total of 77 patients were randomly divided into treatment group and control group. ln the treatment group, ganciclovir ophthalmic gel was topical coated on the basis of antiviral drugs, while the control group was coated with conventional acyclovir ointment and antiviral treatment.
RESULTS: The cure rate was 95% in the treatment group, and the control group was 83% after 10d treatment. The difference was significant.
CONCLUSlON: The efficacy of ganciclovir ophthalmic gel treated eyelid herpes zoster is obvious.
9.Acupuncture intervention combined with assisted reproductive technology: its different effects at different time points during the in vitro fertilization-embryo transfer course.
Jia GUO ; Dong LI ; Qiufang ZHANG
Journal of Integrative Medicine 2008;6(12):1211-6
Recently the combination of acupuncture with assisted reproductive technology (ART) to increase the outcomes of ART is being widely studied. In this article, the literatures concerning random controlled clinical trials since 2002 are reviewed and the designs of the trials, especially the timing of acupuncture, are evaluated. Over the past 5 years, the related clinical trials have primarily showed that acupuncture done immediately before and after embryo transfer might increase the assisted reproduction rates, but still requiring further high quality trials with large samples; in addition, different stimulation modes could produce different result, and so far there has not been a consensus as to the optimal time-point for the acupuncture intervention during the in vitro fertilization-embryo transfer (IVF-ET) course. Since the effects of acupuncture change with women's endocrine cycles, it is important and possible to make a breakthrough in ART outcomes if acupuncture is performed at a suitable time point during the cycle of IVF/ET combined with ART.
10.Osteogenic and adipogenic induction of follicle stem cells in rats
Zhiqiang ZHANG ; Yujie WANG ; Jia LI
Journal of Medical Postgraduates 2014;(4):340-343
Objective Hair follicle stem cells (HFSCs) can be cultured in vti ro to differentiate into chondrocytes, osteoblasts and adipocytes .The aim of the article was to investigate the culture method of HFSCs and their adipogenic and osteogenic differentiation potentials. Methods Microdissection and two-step enzyme digestion were applied to obtain HFSCs , and HFSCs are purified by differ-ential adhesion method.The cells were cultured in keratinocyte serum-free medium obtaining 10% fetal bovine serum.Flow cytometry was used to detect CD34、β1-integrin and CK15.The third-generation HFSCs were cultured by osteogenic inductor and adipogenic induc-tor respectively . Results Cultured HFSCs were homogeneous in shape , bearing the property of great refraction and typical cobble-stone-morph.By flow cytometry, the expression rates of CD34,β1-integrin and CK15 were 59.6%, 97.0%and 61.1%.Stem cells were in good growing condition from the third-generation cell growth curve.21 days after being induced by osteogenic inductor, calcified nodules appeared after alizarin red staining, while 14 days after being induced by adipogenic inductor, intracellular lipid droplets could be observed after oil red O staining. Conclusion Cultured HFSCs are chaterized by strong growth capacity and multiple differentiation potential .