1.Comparative Observation on Effect of Recipes and Medicaments for Spleen-Strengthening and Damp-removing on Chronic Ulceratlve Proctocolltis Allergy
Journal of Traditional Chinese Medicine 1993;0(01):-
rate being 86. 0% cured rate being 60. 0%, remarked-ly higher .than that of the western medication group.100 cases of such patients were randomly divided into 2 groups, each 50 cases. The treating group was treated with spleen-strengthening and damp-removing recipes and medicaments. The cllinical effective
2.Lignan glycosides from Saussurea japonica and rules for substituted effects on ~(13)CNMR chemical shifts of (+)-pinoresinol and (+)-lariciresinol
Chinese Traditional and Herbal Drugs 1994;0(09):-
Object To isolate and identify the chemical constituents of Saussurea japonica (Thunb.) DC. and to obtain some rules of chemical shift effects on hydroxylation and O-glycosylation. Methods The constituents were isolated by silica gel column chromatography and HPLC (RP-18), and their structures were elucidated through spectroscopic analysis (NMR and FABMS). The rules were obtained by comparison with those of known analogous lignans. Results Three lignan glycosides were isolated and identifiedcas (+)-1-hydroxypinoresinol-4″-?-D-glucopyranoside (Ⅵ), (+)-lariciresinol-4-?-D-glucopyranoside (Ⅷ), and (+)-1-lariciresinol-4′-?-D-glucopyranoside (Ⅸ), as well as the rules for effects of the hydroxy group at C-1 (upshift about ??-4.2) and O-glucosylation (downshift about ??+3.0) on 13CNMR chemical shifts of (+)-pinoresinol and (+)-lariciresinol. Conclusion All these compounds were obtained from the plants of Saussurea DC. for the first time and the rules should be as some important evidences to assign the position of hydroxylation and glycosylation.
3.Changes of Plasma Satecholamines and Atrial Natriuretic Peptide in Children with Chronic Heart Failure and Its Clinical Significance
Journal of Applied Clinical Pediatrics 1992;0(06):-
Objective To explore the changes of plasma catecholamines(CA)[including epinephrine(E) and norepinephrine(NE)] and atrial natriuretic peptide(ANP) in children with varying degrees of left ventricular ejection function(LVEF) in chronic heart failure(CHF),and establish natriuretic hormone factors as one of the diagnostic criteria of CHF.Methods Thirty-five patients with CHF and 35 children in good health were enrolled,and the concentration of plasma NE,E,ANP and the LVEF were determined.Results 1.The levels of plasma NE,E and ANP in 35 patients with CHF before treatment were significantly higher than those in control group(Pa
4.Diagnose and treatment of adrenal myelolipoma
Shi RONG ; Bingbing SHI ; Zhigang JI ; Quanzong MAO ; Hanzhong LI
Basic & Clinical Medicine 2006;0(02):-
Objective To review the diagnosis and treatment of adrenal myelolipoma(ML).Methods The medical records of 21 patients with adrenal myelolipoma were reviewed.All patients were examined by B-ultrasound,CT and endocrine tests while some were also examined by MRI and 131I-MIBG.Results All patients had undergone resection of adrenal ML.The mean diameter of tumors was 6.7 cm(4.5 cm~12 cm).Pathological examination of all tumors confirmed the diagnosis of adrenal ML.No recurrence was recorded during the follow-up period(1~15years).Conclusion Adrenal ML is a kind of rare,benign tumor and is often incidentally discovered.Its prognosis is generally good.
6.A qualitative study on the information behavior motivation experience of pregnant women with gestational diabetes
Zengyu SHI ; Chunyan JI ; Chengzhen TAO
Chinese Journal of Practical Nursing 2021;37(5):348-352
Objective:To explore the information behavior motivation of pregnant women with gestational diabetes and provide a basis for constructing an information behavior demand assessment system and health education strategies.Methods:Using the purpose sampling method, from December 2019 to February 2020, semi-structured interviews were conducted on 9 pregnant women with gestational diabetes and 11 pregnant women with gestational diabetes who were hospitalized in the obstetric outpatient department of our hospital, and used Colaizzi's 7-step analysis Methods classify and analyze the data, and extract themes.Results:The analysis extracted 6 themes, namely, information support in the whole process, information expectations, self-care information needs, information credibility, information judgment ability, and behavior change motivation.Conclusion:According to the motivation of information behavior change of pregnant women with gestational diabetes, appropriate educational methods are adopted to stimulate their effective information behavior practice, and targeted nursing care is provided for continuous health education needs.
7.The important role of statins in the prevention and treatment of coronary heart disease
Qi ZHANG ; Xiaoying ZHANG ; Ji SHI
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):349-350
Objective To study the importance of statins in the prevention and treatment of coronary heart disease.Methods167 cases of coronary heart disease in our hospital from December 2013 to November 2014 were chosen as the research object, patients were given different statins such as atorvastatin, rosuvastatin and simvastatin treatment, and total cholesterol(TC),triglyceride(TG), low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol (HDL-C)before and after treatment were statistically analyzed.Results3 months after treatment TC,TG,LDL-C,HDL-C were significantly better than before treatment(P< 0.05);3 months after treatment, 6 months and 12 months, the index value has improved, but the differencehad no statistical significance.ConclusionThe use of statins in coronary heart disease has a significant effect,can improve the clinical indicators.
8.Changes of Chinese Medicinal Properties And Clinical Effects Caused by Chinese Processing
Tianzhu JIA ; Dan XU ; Ji SHI
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(3):450-457
Chinese medicinal decoction pieces were the mainly form for traditional Chinese medicine (TCM) treatment,which means TCM prescription drugs.Any processed (heated or unheated) pieces are known as prepared pieces,which include both raw and cooked pieces.Based on differences of the clinical application of processed pieces,this paper summarized three traditional processing theories,such as the raw and prepared effect difference theory,processing accessories action theory,and pharmaceutical theory.The key points were focused on how different processing methods affect the properties of Chinese herbs,such as four natures and five flavors,floating and sinking,attributive channel,tonifying or purging action,and the toxicity.Based on changes of pharmacodynamic substance base and pharmacological action before and after processing,the action mechanism of processing in changes of Chinese medicinal properties was explained.
9.EMP(English for Medical Purposes) Teaching Practice in the 7-Year-Program Clinical Medicine of Southeast University
Chinese Journal of Medical Education Research 2006;0(11):-
7-year-program clinical medicine is a major that fuses master with bachelor degree education and has higher demand in the integrated ability training.It is in 2002 that Southeast University first admitted students of this major,which,therefore,is brand new challenge to every educators,including EMP teachers.Thus,we initiated teaching innovation and put it into practice,which proved beneficial.
10.Cloning,Expression of E2 Gene in Hepatitis C Virus Envelope Region and Significance of Anti HCV E2 Detection in Patients with HCV Infection
Xuanling SHI ; Feng CHAO ; Yang JI
Chinese Journal of Blood Transfusion 1988;0(01):-
Objective To clone and express the E2 gene in envelope region of hepatitis C virus and detect the anti E2 in sera of patients with HCV infection,using the purified E2 Protein.Methods The gene fragment of E2 region was obtained from the sera of patients with HCV infection by random primer reverse transcription and polymerase chain reaction(PCR),and then cloned into procaryotic expression system to express and Purify the protein and detect its antigenicity.Results A segment of E2 region gene with correct code reading frame was obtained,its full length was 984 bp and molecular weight of expressed Protein was 38kD.The detection of the protein performed by ELISA with sera from the patients with HCV infection,testified that it had appropriate antigenicity.Conclusion This experiment can provide the fundamental data for researching on the basic characteristics of HCV envelope protein,nuderstanding the significance of serological diagnosis and designing the anti HCV vassine.