Ectopic thymus results from the aberrant migration of thymic tissue and is mostly present in the mediastinum, the base of the skull, the tracheal bifurcation and the cervical region. We report the first case of intraabdominal heterotopic thymus incidentally detected and attached to the liver without associated anomalies. This fetus was sent to the Department without any clinical information. The fetus was small for gestational age, but had no external abnormalities. Each organ showed normal development except for the liver. The liver weighed 6 gm(normal 17.064+/-4.143 gm). Gray white heterotopic thymus was attached to the superior surface of the liver in the subdiaphragmatic area. It measured 1.1x0.6x0.5 cm. There was no diaphragmatic defect. The cervical thymic tissue near the thyroid was small and measured 0.2 gm(normal 0.927+/-0.485 gm). There was no thymic tissue in the anterior superior mediastinum. The histologic features of the heterotopic thymus were identical to the orthotopic thymus showing features appropriate for the gestational age. The origin of this subdiaphragmatic heterotopic thymus is speculated.

Present study describes two rare spermatic cord sarcomas. The first case is leiomyosarcoma of a 56-year-old man with 3-years' history of slowly growing hard mass in the right inguinal area, measuring 8x6x5 cm. The second case is fibrosarcoma of a 39-year-old man with 3x2 cm painless right inguinal mass. Both cases underwent radical excision of mass and orchiectomy. Clinico-pathologic characteristics of spermatic cord sarcoma are discussed with literature review.
Adult ; Fibrosarcoma ; Humans ; Leiomyosarcoma ; Middle Aged ; Orchiectomy ; Sarcoma* ; Spermatic Cord*

No abstract available.
Adenomatous Polyposis Coli*

The biochemical study of the nutritional status of 101 healthy pregnant women and cord blood samples showed that maternal serum protein, albumin, hemoglobin (Hb), iron (Fe), zinc (Zn) and calcium (Ca) were decreased, and serum transferrin and copper (Cu) were increased in the course of gestation.Correlation coefficients and stepwise regression analysis suggested that the concentrations of serum protein, Fe, Zn, Ca,Hb were positively correlated with the intake of calories, proteins, animal foods (especially fish and meats), Ca and vitamin C.The concentration of cord blood Ca,Zn and Fe were found highly related to the maternal serum levels in the late stage of pregnancy (P

Eight parameters about iron nutrition were observed longitudinally in eighty pregnant women from the first trimester to delivery. Their nutrients intake were recorded at the same time. It was noted that serum iron store (ferritin) decreased markedly in the course of pregnancy and the incidence of iron deficiency increased. Total iron intake was closely related to the variation of these parameters, the degree of iron deficiency in pregnant women and the content of cord ferritin. Iron in maternal serum is correlated to ferritin in the cord blood. It suggested that natural food abundant in iron, or food fortified with iron should be taken in early pregnancy to prevent iron deficiency of mothers.

This study was undertaken to observe the effects of centrally administred antihistamines on the blood pressure. Diphenhydramine(DPH), a H1-receptor antagonist, and ranitidine(RAN), a H2-receptor antagonist were administered intracerebroventricularly(icv) on urethane-anesthetized rabbits. 1) Both DPH and RAN administered intraccebroventricularly increased blood pressure, however the intravenous(iv) adminstration of them did not affect blood pressure. The pressor response to icv DPH was dose-dependent, but that to icv RAN was not. 2) The pressor response to icv DPH(1mg) was either markedly attenuated or reversed to depressor response by the pretreatment with icv phentolamine(250,500ug), and iv chlorisondamine(0.1, 1mg/Kg) and iv phenoxybenzamine(1mg/Kg). In cord-sectioned rabbtis, icv RAN) 1mg) did not produce pressor response. 3) The pressor responsr to icv RAN(1mg) was not affected by the pretreatment with icv phentolamine(500ug), iv chlorisondamin(1mg/Kg) and iv phenoxybenzamine(1mg/Kg), and iv phenoxybenzamine(1mg/Kg). RAN also producted pressor response in cordsectioned rabbits. These results suggest that the pressor response to icv DPH is elecited by increasing peripheral sympathetic tone via the stimulation of central alpha-adrenoreceptors and the pressor response to icv RAN is produced by releasing some humoral facotr which can increase blood pressure.
Blood Pressure ; Diphenhydramine* ; Histamine Antagonists ; Rabbits* ; Ranitidine*

Authors have experienced 27 cases of traumatic hyphemas in our department for recent years. All the patients was taken systemic administration of Diamox as ocular hypotensives, prednisolone as anti-inflammatory agent and hemostatics, and antihistaminics for neutralize the histamin like substance which may emerge after vascular injury by trauma, without any surgical procedures or other medication. The result of treatment satisfactory as hyphemas were absorbed clerly within short period without any complication and visual deterioration.
Acetazolamide ; Hemostatics ; Humans ; Hyphema* ; Prednisolone ; Vascular System Injuries

We compared the differences of the intraocular pressure measured by the applanation and the Schiotz tonometer according to the ocular rigidity and its changes. We also did it by sex difference, age and the ocular rigidity range. The Korean 254 normal eyes, 12 aphakic eyes, 32 mydriatics treated eyes and 102 myopic eyes were examined. The intraocular perssure was measured by Goldmann applanation tonometer and Schiotz indentation tonometer using the 5.5 gram and 10.0 gram plunger load successively. The ocular rigidity was estimated from the Moses and Becker table. The results were as follows: 1. The mean ocular rigidity of the male and the female Korean was 0.0157 and 0.0195, respectively. There was no significant differences between the two tonometric values. 2. There was no significant ocular rigidity changes according to ages, and there was no statistically significant differences between the two tonometric values, 3. There was no statistically significant differences between the two tonometric values according to the ocular rigidity range. 4. The mean ocular rigidity of normal eyes, aphakic eyes. mydriatics treated eyes and myopic eyes was 0.0183 0.0166, 0.0164 and 0.0170, respectively, and there was no significant differences between the two tonometric values in each groups.
Female ; Humans ; Intraocular Pressure ; Male ; Manometry* ; Mydriatics ; Sex Characteristics

The relaxant response of endothelium dependent vasodilator substances on the corpus cavernosum is not completely defined yet in spite of many research works. The aim of this study was to determine the effects of vasodilator substances which were endothelium dependent to the blood vessels of rabbit corpus cavernosum. 8 male New Zealand white rabbit were used. One side of corpus cavernosum was dissected free of the tunica albuginea for endothelium intact control strip and another side of corpus cavernosum for endothelium removed strips. Removal of corpus cavernosal endothelium was achieved by rubbing between the thumb and index finger for 3 minutes. Corporal strips were mounted in organ bath and changes of isometric tension were recorded with force-displacement transducer, which were connected to grass polygraph, The effects of acetylcholine, bradykinin, substance-P, histamine and ATP were observed on endothelium intact control and endothelium removed strips. Acetylcholine, bradykinin, substance-P and ATP relaxed control strips which were pre-stimulated by norepinephrine, but there were no relaxant response on endothelium removed strips except ATP The control strips showed weak relaxation response to ATP at high concentration. Histamine contracted both intact and endothelium removed strips which were pre-contracted by norepinephrine. In conclusion, the relaxant responses of acetylcholine, bradykinin, substance-P, and ATP on the rabbit corpus cavernosum were endothelium dependent.
Acetylcholine ; Adenosine Triphosphate ; Baths ; Blood Vessels ; Bradykinin ; Endothelium* ; Fingers ; Histamine ; Humans ; Male ; New Zealand ; Norepinephrine ; Poaceae ; Relaxation ; Thumb ; Transducers

Prenatal chromosome analysis of amniotic cells at 18 weeks of gestation showed a male fetus to carry a large 15p+ derivative chromosome inherited from his mother. Extra genetic material on the short arm of chromosome IS was silver-negative with Ag-NOR (nucleolus organizer regions) stain, but stained darkly with C-banding method like the distal heterochromatic segment of the Y long arm. Fluorescence in situ hybridization (FISH) using two DNA probes (DYZ1 and D15Zl) showed a red fluorescent signal on 15p+ In addition to a green chromosome 15 centromere signal, confirming 15p to be from the distal Yq heterochromatin.
Arm ; Centromere ; Chromosomes, Human, Pair 15 ; DNA Probes ; Fetus ; Fluorescence ; Heterochromatin ; Humans ; In Situ Hybridization ; Male ; Mothers ; Pregnancy