Early Diagnosis of the Trophoblastic Disease The study comprised 40 cases (15.7%) of chorionepithelioma and 214 cases (84.3%) of hydatidiform mole. According to our study (1992-2001), the incidence of trophoblastic disease, including chorionepithelioma, does not appear to reduce. Clinical characteristics of the trophoblastic disease strongly depend on the type of clinical variant. Chorionepitheliomas were associated with uterine bleeding and rapid spread to lungs, while hydatidiform moles were associated with expulsion of vesicles along with blood from the uterus and disagreement between the uterine size and gestational dates. Women older than 40 years (OR=2.31), and with history of 5 and more pregnancies and deliveries (OR=1.21 and OR=2.38), induced abortions (OR=1.41), and miscarriages (OR=1.03) have a greater chance of presenting with chrioepitheliomas than with hydatidiform moles. Because uterine bleeding is the main symptom of trophoblastic disease, which therefore can be confused with miscarriage, dysfunctional uterine bleeding, retained placenta and endometritis, evacuation of the uterus and sending the evacuate to pathology for confirmation is an important practice (Р<0.01). During trophoblastic disease, blood B-hCG levels dramatically increase. Levels of -hCG are higher and take more time decreasing to normal levels in chorionepitheliomas compared with hydatidiform moles, indicating that measuring B-hCG provides many advantage in monitoring the disease and treatment outcomes.

The Rhythm of the Normal and Abnormal Deliveries of the Mongolian Womens Normal deliveries of mongolian women have orderly rhythmic oscillations which can be characterized by 24 hours, months, seasons and years. In the complicated deliveries the phases of biorhythms have been shifted and resulted in desynchronosis. Climatic and geliogeophizic factors had also effect on the frequency of complicated deliveries. Among common complications of the delivery and childbirth, preeclampsia, prolonged labor or dystocia due to insufficient labor and delivery forces, obstetric hemorrhage show seasonal and multi-year rhythms' characteristic to geographical regions and climatic conditions.
Delivery ; Obstetric ; Uterine Contraction

Objectives: The goal of this study is to evaluate expression of the HPV16/18 L1 in cervical tissues in correlation with lesion grade. Methods:A total of 96 specimens were analyzed in this study. There were 50 cases diagnosed as low-grade squamous intraepithelial lesion (LSIL) and 46 cases diagnosed as high-grade (H-) SIL. All cases were submitted for immunohistochemistry with anti-HPV16 /18 L1 antibody. Results: The positive rate of HPV16 L1 and HPV18 L1 was identified in 61 (64%) and 21 (22%) of all cases. There was a statistically significant difference for HPV18 (X2 = 0.599, p<0.05), but not for HPV16 (X2 = 0.024, p>0.05) in the two SIL groups. In addition, 27 cases had no HPV16/18 L1 expression and 13 cases had HPV16/18 L1 co-expression. Conclusion: Lack of HPV L1 capsid protein in cervical lesions may serve as a prognostic marker of enhanced malignant potential. There is still a critical need to find other molecular surrogate markers, which can provide accurate information about which precursor lesions would progress toward cancer.