A 52-year old lady presented with acute onset headache, seizures, confusion and was found to
have anemia, albumin/globulin ratio reversal and cerebral venous sinus thrombosis. On further
investigations, multiple myeloma was found to be the underlying cause. The patient recovered fully
with anticoagulation and chemotherapy. This case indicates that cerebral venous sinus thrombosis can
be an unusual presenting manifestation of myeloma.
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