INTRODUCTION: Atherosclerotic diseases wherein obesity is a risk factor was shown to be the leading causes of mortality according to statistics. Body mass index (BMI), waist hip ratio (WHR) and waist circumference (WC), measurements of adiposity, were consistently identified as good measures of cardio-metabolic health risks. High-resolution B-mode ultrasound measurements of carotid intima-media thickness (CIMT) have also been used as a reliable and reproducible method to detect preclinical atherosclerosis, a precursor of cardiovascular disease.

OBJECTIVE: This study aims to investigate which of the measurements of adiposity would best correlate with early vascular changes primarily noted in the CIMT among non-high risk clinicians of Victor R. Potenciano Medical Center (VRPMC).

METHODS: A total of 38 subjects out of 42 residents and interns of VRPMC volunteered to participate in the study from August to November 2010. They had no evidence of cardiac or vascular disease. The weight, height, WC, and hip circumference of each subject were measured. High-resolution B-mode ultrasonography of the right and left common carotid arteries was then performed. 

RESULTS: A weak correlation between BMI with CMIT was found. There is no association between WC and WHR and thickness of CIMT.

CONCLUSION: WC, BMI, and WHR are insignificantly associated with CIMT in this study. 

Human ; Male ; Female ; Adult ; Adiposity ; Atherosclerosis ; Cardiovascular Diseases ; Carotid Artery, Common ; Carotid Intima-media Thickness ; Obesity ; Risk Factors

BACKGROUND: The modified Ferriman-Gallwey (mFG) score is the gold standard for the clinical evaluation of hirsutism. However, racial variations in terminal hair growth limit this tool. This study aimed to determine the mFG cut-off score among Filipino women and its association with biochemical hyperandrogenism.METHODS: A total of 128 Filipino women were included in this prospective cross-sectional study and were divided into two groups: a polycystic ovary syndrome (PCOS) group (n=28) and a non-PCOS group (n=100). The participants underwent mFG score determination, ovarian ultrasound conducted by a single sonographer, and hormone testing. The mFG cut-off score was determined based on the 95th percentile of the non-PCOS group. Logistic regression was used to analyze the relationship between mFG score and biochemical hyperandrogenism.RESULTS: Although the mFG score was generally low in both the PCOS and non-PCOS groups, the former exhibited a higher mean score than the latter (4.3±3.0 vs. 2.0±2.2, P<0.001). Normal values for the total mFG score ranged from 0 to 7. Using a cut-off score of 7, a higher proportion of hirsute women (mFG score ≥7) was observed in the PCOS group versus the non-PCOS group (17.9% vs. 5.0%, P=0.025). Elevated calculated free testosterone (FT) was also found to be significantly associated with hirsutism (odds ratio, 6.2; 95% confidence interval, 1.2 to 32.4 pmol/L; P=0.030).CONCLUSION: A score of 7 and above constitutes hirsutism in this population of Filipino women. Hirsute women are more likely than non-hirsute women to have elevated calculated FT.
Cross-Sectional Studies ; Female ; Gonadal Disorders ; Hair ; Hirsutism ; Humans ; Hyperandrogenism ; Logistic Models ; Polycystic Ovary Syndrome ; Prospective Studies ; Reference Values ; Testosterone ; Ultrasonography