1.THERAPEUTIC EFFECT OF ENRICHED SOYBENA HIGH BRANCHED CHAIN AMINO ACID MIXTURE(II) ON SCALDED RATS
Academic Journal of Second Military Medical University 1985;0(06):-
The enriched soybean high branched chain amino acid mixture (II) was a special hydrolytic soybean protein enriched with a small amount of individual amino acids. The content of its essential amino acids was 68.89% and branched chain amino acids 42.85%.The results of this experiment show that the mixture (II) can improve negative nitrogen balance and elevate the level of serum albumin, and is a good nitrogen source for elemental diet after trauma.
2.Short-term efficacy and safety of concurrent chemoradiotherapy with paclitaxel and lobaplatin for advanced esophageal cancer
Journal of International Oncology 2015;42(1):10-13
Objective To evaluate the short-term efficacy and safety of concurrent chemoradiotherapy (CCRT) with paclitaxel and lobaplatin for advanced esophageal cancer.Methods Sixty-eight patients with advanced esophageal cancer were randomly divided into two groups according to random number table method:CCRT with paclitaxel and lobaplatin (TL group) and CCRT with DDP and 5-Fu (PF group).The CCRT regimen included radiotherapy at a total dose of 60-70 Gy,and concurrent paclitaxel 60 mg/m2 on d1,a fraction per week for 6-8 weeks,lobaplatin 30 mg/m2 on d2,a fraction per 3 weeks (TL group),and concurrent DDP 75 mg/m2 on d1,5-Fu 500 mg/m2,d1-5,CF 200 mg/m2,d1-5 (PF group).Results All 68 patients were evaluable for response.The response rates were 73.53% in TL group and 50.00% in PF group,the median progression-free survival were 13.0 months in TL group and 6.5 months in PF group.There were significant differences (x2 =4.023,P =0.040; x2 =4.512,P =0.034).The incidence rates of Ⅲ-ⅣW degree nausea and vomiting,granulocytopenia and thrombocytopenia were 5.88% and 35.29%,20.59% and 32.35%,32.35% and 8.82%,and the differences were statistically significant (x2 = 8.500,P =0.003 ; x2 =3.200,P =0.041; x2 =6.710,P =0.016).The incidence rates of Ⅲ-Ⅳ degree esophagitis in the two groups were 11.76% and 17.65%,and there was no significant difference (x2 =1.45,P =0.493).Conclusion The efficacy of TL group in the treatment of advanced esophageal cancer is excellent,and all toxicities are well tolerated.So this protocol may be considered a main regimen in the treatment of advanced esophageal cancer.
3.Development of A Constuctive Thinking Scale for Pupils
Chinese Journal of Clinical Psychology 2006;0(06):-
Objective: To develop a Constructive Thinking Scale for Chinese pupils. Methods: Data were collected from a sample of 302 primary school pupils tested with the Constructive Thinking Scale. Results: ①Item analysis showed that the Constructive Thinking Scale had satisfactory item discrimination; ②The Constructive Thinking Scale had a satisfactory reliability with a 0.83 test-retest reliability, and the Cronbach’s ? was 0.88; ③The result of EFA had five factors, and the range of factor loading was between 0.36 and 0.75. The final revised questionnaire included 23 items, which could explain 53.13% of the total variances. The scale had an ideal criterion validity. Conclusion: The Constructive Thinking Scale for pupils has ideal reliability and validity, and can be used in assessing Chinese pupils’ constructive thinking .
4.Development of Emotional Intelligence Scale for Pupils
Chinese Journal of Clinical Psychology 2006;0(06):-
Objective:To develop an Emotional Intelligence Scale for Chinese pupils.Methods:Data were collected from a sample of 288 primary school students tested by the Emotional Intelligence Scale.Results:①Item analysis showed that the Emotional Intelligence Scale had satisfactory item discrimination.② The Emotional Intelligence Scale had a satisfactory reliability with a 0.90 test-retest reliability and the Cronbach's ? was 0.89.③The result of EFA had five factors,and the range of factor loading was between 0.40 and 0.77.The final revised questionnaire included 25 items,explaining 54.33% of the total variances.④The result of independent-sample t test showed significant gender differences in emotional intelligence.Conclusion:The Emotional Intelligence Scale for pupils has ideal reliability and validity.
6.The trial of hypocaloric parenteral nutrition combined with recombinant human growth hormone in gastrointestinal tumor patients after operation
Parenteral & Enteral Nutrition 1997;0(01):-
Objective:To investigate the changes in protein metabolism after the use of recombinant human growth hormone(rhGH) in gastrointestinal tumor patients after operation.Methods:Thirty-nine patients with gastrointestinal tumor were randomly(double-blind) divided into two groups: ①the control group(n=20),which was treated with hypocaloric parenteral nutrition and placebo,②the rhGH group(n=19),which was treated with hypocaloric parenteral nutrition and rhGH.The levels IGF-1 and protein metabolism were observed.Results:The concentrations of IGF-1,pre-albumin,transferrin and fibronectin were decreased in the two groups on the 3th day after operation.The administration of rhGH resulted to significant increase in serum levels of IGF-1,pre-albumin,transferrin and fibronectin.Conclusion:The administration of recombinant human growth hormone can increase the protein synthesis and improve the nutritional condition.
7.Application of different nutritional supports in gastric cancer patients undergoing radical resection
Parenteral & Enteral Nutrition 1997;0(01):-
Objective:To evaluate the effects of different nutritional supports in gastric cancer patients undergoing radical resection.Methods:Sixty patients with gastric cancer were randomly divided into three groups: parenteral nutrition(PN)group,enteral nutrition(EN) group and parenteral nutrition combined with enteral nutrition(PN-EN) group.The rate of complication, recovery time of the gut function,average post-operative hospital stay,changes of liver function,levels of blood glucose,serum albumin,prealbumin and transferrin,levels of nitrogen balance and change of body weight were observed in the three groups.The therapeutic effects of post-operational nutritional support were studied.Results:There are no significant difference in the rate of complication,average post-operative hospital stay,changes of liver function and level of blood glucose.The recovery time of the gut function in EN group was shorter than that in PN and PN-EN groups(P
8.The roles and mechanism of tumor-derived factors in the development of cancer cachexia
Parenteral & Enteral Nutrition 1997;0(04):-
Syndrome of cachexia,which is a common feature of many types of cancer,characterized by loss of adipose tissue and skeletal muscle,is responsible not only for a poor quality of life and poor response to chemotherapy,but also a decreased survival time.It can not be fully explained by the accompanying anorexia,because increasing nutrient support is unable to reverse the wasting syndrome.Although patients with cachexia frequently show an elevated resting energy expenditure,cachexia can occur with a normal energy expenditure.Lipid mobilizing factor and proteolysis inducing factor,two tumor-derived factors,can directly mobilize fatty acids and amino acids from adipose tissue and skeletal muscle respectively.It is important of the knowledge about the roles and mechanism of LMF and PIF in the development of cancer cachexia,which should lead to the development of new therapeutic methods.
9.The new progresses in the clinical application of probiotics
Parenteral & Enteral Nutrition 2004;0(05):-
Probiotcs are viable organisms or bacterial meal replenishers that do good to our body.They have multiple functions like improving internal gut environment,reinforcing immunity,antitumors,and are more and more widely used in clinical studies to cure some diseases,such as IBD,pouchitis,infective diarrhea and so on.This review is about the new progress in the acting mechanism and clinical application of probiotics.
10.Clinical characteristics of acute myocardial infarction with leukocytosis and their significances
Clinical Medicine of China 2000;0(11):-
Objective To study the relationship between the white blood cell (WBC) count of peripheral blood at the early stage of acute myocardial infarction (AMI) and the prognosis.Methods 100 cases of AMI were divided into normal WBC counts and elevated WBC counts group.Clinical characteristics of the two groups were compared.Results The cases of AMI with leukocytosis is apt to complicate left ventricular failure,arrhythmia and excitable hyperglycemia.The peak value of CK and ECG QRS scoring as well as mortality were elevated.Conclusion The WBC has an important prognostic significance in AMI.