Objective:To study the effects of different molecular weight of collagen polypeptides from Apostichopus japonicus (A1:6 000U

Objective To investigate the relationship between head nurse's authentic leadership and degree of solidarity among nurses in operating room.Method A total of 120 nurses in the operation room of 3 general hospitals in Jiamusi City were enrolled in the study by way of the questionnaire on authentic leadership and the scale of solidarity.Results The mean score on the head nurse's authentic leadership (41.28 ± 8.48) was above the middle-high level.The mean score on the solidarity (68.67 ± 8.82) was in the middle-high level.There was a positive correlation between the head nurses' authentic leadership and the degree of solidarity among nurses in the operating room.Conclusion Hospital and nursing administrators should take active and effective measures to improve the leadership of head nurses so as to improve the degree of solidarity among nurses in the operating room as well as the quality of nursing.

Objective: To investigate the resistance to rifampicin and isoniazid and the changing trends among patients with pulmonary tuberculosis in Luohu District, Shenzhen City, Guangdong Province from 2012 to 2022, so as to provide insights into improving drug-resistant pulmonary tuberculosis control and prevention strategies. Methods: Basic information, treatment classification and drug resistance data of patients with pulmonary tuberculosis and positive pathogenic detection in Luohu District from 2012 to 2022 were collected through the Tuberculosis Surveillance System of Chinese Disease Prevention and Control Information System, and resistance rates of rifampicin and isoniazid and the changing trends were analyzed. Results: A total of 2 126 patients with pulmonary tuberculosis were collected and had a median age of 34 (interquartile range, 25) years, including 1 334 males (62.75%) and 792 females (37.25%). There were 302 patients with drug-resistance in Luohu District from 2012 to 2022, with a resistance rate of 14.21%. Among them, 60 patients were monoresistant to rifampicin (2.82%), 113 patients were monoresistant to isoniazid (5.32%), and 129 patients were multidrug resistant (6.07%). The rate of rifampicin monoresistance showed a downward trend from 2012 to 2022, while the rate of multidrug resistance showed an upward trend (both P<0.05). There was no significant tendency in the rate of isoniazid monoresistance (P>0.05). The rate of multidrug resistance among patients without Shenzhen residence was higher than that among patients with Shenzhen residence; the rates of rifampicin resistance and multidrug resistance among retreated patients were higher than those among treatment-naïve patients (all P<0.05). Conclusions The rate of rifampicin monoresistance appeared a downward trend and the rate of multidrug resistance appeared an upward trend among patients with pulmonary tuberculosis in Luohu District from 2012 to 2022. Attention should be given to non-Shenzhen residence and retreated patients.

Objective:To investigate the value of musculoskeletal ultrasound examination in the evaluation of rheumatoid arthritis.Methods:A total of 89 patients with rheumatoid arthritis who received treatment in Zhejiang Rongjun Hospital from January 2020 to January 2023 were included in this study. According to the Disease Activity Score-28 for Rheumatoid Arthritis, these patients were divided into a low activity group ( n = 32), a medium activity group ( n = 36), and a high activity group ( n = 21). An additional 32 healthy controls who concurrently underwent physical examinations in Zhejiang Rongjun Hospital were included in the control group. All participants underwent a musculoskeletal ultrasound examination. Serum interleukin-1β, interleukin-6, and interleukin-23 levels were determined by an enzyme linked immunosorbent assay. Results:In the rheumatoid arthritis group, semi-quantitative scores of musculoskeletal ultrasound in terms of joint effusion, bone erosion, synovial blood flow signal, synovial hyperplasia, and total scores were (1.53 ± 0.36) points, (1.70 ± 0.45) points, (1.75 ± 0.38) points, (1.98 ± 0.42) points, and (6.97 ± 1.43) points, which were significantly higher than (0.11 ± 0.03) points, (0.14 ± 0.02) points, (0.07 ± 0.03) points, (0.15 ± 0.04) points, and (0.47 ± 0.08) points in the control group ( t = 22.23, 19.55, 24.92, 24.54, 25.63, all P < 0.05). Serum interleukin-1β, interleukin-6, and interleukin-23 levels in the rheumatoid arthritis group were (66.49 ± 15.45) ng/L, (12.33 ± 3.27) ng/L, and (206.85 ± 24.37) ng/L], which were significantly higher than (15.42 ± 4.36) ng/L, (6.58 ± 1.39) ng/L, and (124.52 ± 18.29) ng/L in the control group ( t = 18.39, 9.62, 17.41, all P < 0.05). The semi-quantitative scores of musculoskeletal ultrasound in terms of joint effusion, bone erosion, synovial blood flow signal, synovial hyperplasia, and total scores in the high activity group were significantly higher than those in the medium activity and low activity groups, and the semi-quantitative scores of musculoskeletal ultrasound in terms of joint effusion, bone erosion, synovial blood flow signal, synovial hyperplasia, and total scores in the medium activity group were significantly higher than those in the low activity group (all P < 0.05). Serum interleukin-1β, interleukin-6, and interleukin-23 levels in the high activity group were significantly higher than those in the medium activity and low activity groups, and the scores in the medium activity group were significantly higher than those in the low activity group (all P < 0.05). According to Spearman analysis, the semi-quantitative total score of musculoskeletal ultrasound was positively correlated with the severity of disease activity, interleukin-1β, interleukin-6, and interleukin-23 ( r = 0.68, 0.57, 0.52, 0.62, P < 0.05). Conclusion:Musculoskeletal ultrasound is of good value in the evaluation of rheumatoid arthritis. Musculoskeletal ultrasound results are closely related to the degree of rheumatoid arthritis and inflammatory factors.

OBJECTIVETo explore an economical and practical storage method for angelica roots (Angelica sinensis). Various treatments were used in packaging and storing dry and fresh angelica roots.

METHODThe experiment was designed in single-factor completely random as compared with the traditional stack without package. The character, weight, extract contents and volatile oil were measured within the storage process.

RESULTIf stored for long-term use, the dried angelica roots should be packaged with vacuum-exhausted bags cleaned with water, which resulted in less loss in weight, higher extracts and volatile oil. However, if stored for fresh use, the fresh angelica roots should be packaged in vacuum-exhausted bags after cleaned with sorghum alcohol and stored under low temperatures if possible, which resulted in less loss in weight and longer fresh time. Considering volatile oil and extract contents, it is better to use the dried angelica roots for storage.

CONCLUSIONIf stored for long-term use the dry angelica roots should be packaged with vacuum-exhausted bags cleaned with water, while for fresh use the fresh angelica roots should be packaged with vacuum-exhausted bags cleaned with sorghum alcohol and stored under low temperatures if possible.

Angelica sinensis ; Drug Packaging ; economics ; methods ; Drug Storage ; economics ; methods ; Drugs, Chinese Herbal ; Plant Roots ; Quality Control ; Time Factors

The wide use of crystalline silicon solar cells in the field of new energy is an important boost for China to achieve the environmental protection goal as soon as possible. However, the production and manufacturing processes of these cells give rise to various occupational hazards at workplace, thus posing health risks to workers. This review provided an overview of production processes of crystalline silicon solar cells, the characteristics of occupational health hazards (productive dust; physical factors, productive toxicant) and proposed occupational protection suggestions.

Objective To investigate the status quo of professional autonomy and job satisfaction of specialiized nurses in Operating Room, and analyze the correlation between them.Methods In August 2016, totally 130 nurses of Operating Room in Heilongjiang Province were selected as the research object. Nursing work behavior scale and job satisfaction scale were used to investigate.Results The total score of professional autonomy was (170.21±18.36), and the total score of job satisfaction was (3.35±0.58). There was a positive correlation between professional autonomy and job satisfaction (r=0.390,P<0.05).Conclusions The professional autonomy of the specialized nurse in the Operating Room is at the middle level, the job satisfaction of specialized nurse in Operating Room is at a moderately high level. The nursing administrators take advantage of multiple paths to improve the autonomy of specialized nurse in Operating Room, create a good working environment and improve their job satisfaction.

The wide use of crystalline silicon solar cells in the field of new energy is an important boost for China to achieve the environmental protection goal as soon as possible. However, the production and manufacturing processes of these cells give rise to various occupational hazards at workplace, thus posing health risks to workers. This review provided an overview of production processes of crystalline silicon solar cells, the characteristics of occupational health hazards (productive dust; physical factors, productive toxicant) and proposed occupational protection suggestions.

Objective:To explore the application effect of the health management mode based on symptom group management in the nursing of lung cancer patients after minimally invasive surgery.Methods:The lung cancer patients underwent minimally invasive surgery and were discharged from Shanghai Chest Hospital from April to August 2019 were selected as the study subjects. The patients were divided into control group and experimental group, with the intervention time of 1 month. Routine follow-up was carried out in the control group. The health management mode based on symptom group management was adopted in experimental group. According to the exploratory factor analysis method, three factors with characteristic value>1were extracted, and the symptoms with factor load≥0.5 were included in the symptom group, and post discharge nursing was carried out based on the symptom group, including establish health management archives, distribute symptom group manual, centralized teaching, WeChat communication, etc. Before and after nursing care, Anderson symptom evaluation form (Chinese version) was used to evaluate the symptom group score of patients and compare the interference of symptom group on daily life and the influence on quality of life.Results:A total of 40 cases (47.1%) in the control group and 45 cases (52.9%) in the experimental group were included. In the control group, 28 cases (70.0%) were male, 12 cases (30.0%) were female, the average age was (60.2±6.5) years, the average time of cancer was (8.0±2.0) months, and 21 cases (52.5%) had a history of smoking. In the experimental group, there were 30 (66.7%) males, 15 (33.3%) females, age (60.6±6.8), mean time of cancer (7.9±2.1) months, and 22 (48.9%) smokers. There was no significant difference in gender, age, average time of cancer and smoking history between the two groups (all P>0.05).There was no significant difference in factor load of those symptoms between the two groups before nursing, and there was no significant difference before and after nursing in the control group. After the intervention, the symptoms in the experimental group were less than before the intervention. The total scores of symptom group and disturbance of daily life in the experimental group were (32.4±10.3), (15.20±5.3), lower than those in the control group (44.3±11.5), (28.8±8.1), the quality of life score was (88.3±18.5), higher than that in the control group (64.2±16.5) (all P<0.05). Conclusion:The health management model based on symptom group management can improve the symptoms of patients with lung cancer after minimally invasive surgery, reduce the impact of symptom group on daily life and improve the quality of life.

Objective To in vitro culture glial lineage progenitor cells derived from periventricular white matter in neonatal rats,and establish oxygen-glucose deprivation models of progenitor cells to further explore the mechanism of neurogenesis in the ischemic white matter injury.Methods The progenitor cells were isolated and cultured from the white matter of 3-d-old neonatal rats.Cells were passaged every 3 or 4 d,and were further induced differentiation.The primary and passaged neurospheres and their differentiated cells were respectively identified by immunocytochemical stanning of NG2 (Neurospheres marker) and O4 (oligodendrocyte precursor marker).The third-or fourth-generation progenitor cells were used to establish the ischemic model of oxygen-glucose deprivation (OGD).The influence of different OGD periods (30,45 and 60 min,2 and 3 h) in the survival rates of progenitor cells was assessed 24 h after success of model making by both CCK-8 and Hoechst 33342/PI stainning.Results The progenitor cells obtained from the white matter had the capacity of forming neurospheres and reproduction which showed NG2 immunoreactive positivity,and could be induced differentiation into O4-positive oligodendrocyte precursors.No apoptotic or necrotic cells were observed in normal cultured NG2-positive progenitor cells.The apoptotic and necrotic cells tended to increase significantly with the extension of OGD period gradually.The survival rates of progenitor cells in turn were (85.94±3.06) ％ for 30 min OGD,(62.68±2.66) ％ for 45 min OGD,(45.09±2.24) ％ for 60 min OGD,(36.70±2.84) ％ for 2 h OGD and (22.01±3.00) ％ for 3 h OGD,respectively,with significant differences between each two groups (P＜0.05).Conclusion The oxygen-glucose deprivation models of glial lineage progenitor cells derived from periventricular white matter of neonatal rats are successfully established,which may provide the foundation for further exploring the mechanism of neurogenesis in the ischemic white matter injury.