No abstract available.
CpG Islands* ; Methylation*

No abstract available.
Adenoma* ; Aged* ; Cartilage* ; Female ; Humans ; Islands*

Follicular hamartoma is a rare, benign adnexal tumor with varieties of clinical diversity. But, Histological feature is characterized by a proliferation of immature hair follicle in the dermis with multifocal islands and thickened perifollicular sheath. Pili multigemini is also a rare, developmental anomaly of hair growth with multiple hairs from two or more matrices and papillae in a single pilosebaceous unit. Its prevalence and pathogenesis are unknown. We describe herein a rare case of localized follicular hamartoma with pili multigemini suggesting the possibility of association on pathogenesis between them.
Dermis ; Hair ; Hair Follicle ; Hamartoma* ; Islands ; Prevalence

No abstract available.
Islands* ; Jeollanam-do* ; Primary Health Care* ; Ships*

The wood-rotting fungi of three Korean islands in the Yellow Sea, Soyeonpyung-do (SY), Oeyeon-do (OY), and Gageo-do (GG), were investigated from October 2004 to November 2005. During four sampling trips on each island, a total of 46, 44, and 44 specimens were collected from SY, OY, and GG, respectively. The identified wood-rotting fungi from SY included 29 species of 22 genera and nine families; OY had 31 species of 26 genera and 10 families; and GG had 34 species of 27 genera and 11 families. The majority of the fungi were in the Polyporaceae, which was represented by 23 genera and 30 species. Auricularia polytricha, Daedaleopsis tricolor, Daldinia concentrica, Hymenochaete cinnamomea, Hymenochaete yasudai, Hyphoderma setigerum, Lopharia mirabilis, Schizopora paradoxa, and Trametes versicolor were collected from all three islands.
Fungi ; Humans ; Islands ; Korea ; Mirabilis ; Polyporaceae ; Trametes

In forensic science practice, age is an important individual information, and one of the indicators to be considered first to depict features of the suspect. Recently, DNA methylation has become a research hotspot in age estimation because of its hig accuracy and stability. New progress has been made in specificity of DNA methylation sites, age estimation in multiple tissues, DNA methylation age estimation of minors, sensitivity of age estimation, forensic practical applications, etc. At the same time, several studies also established more accurate statistical modeling methods, eliminated differences between different detection platforms, found appropriate number of sites in models and analyzed the influence of environment and diseases. This review summarizes these to provide references.
CpG Islands ; DNA Methylation ; Forensic Genetics ; Humans

PURPOSE: This study evaluated the spontaneous healing capacity of surgically produced cranial defects in rabbits with different healing periods in order to determine the critical size defect (CSD) of the rabbit cranium. METHODS: Thirty-two New Zealand white rabbits were used in this study. Defects of three sizes (6, 8, and 11 mm) were created in each of 16 randomly selected rabbits, and 15-mm defects were created individually in another 16 rabbits. The defects were analyzed using radiography, histologic analysis, and histometric analysis after the animal was sacrificed at 2, 4, 8, or 12 weeks postoperatively. Four samples were analyzed for each size of defect and each healing period. RESULTS: The radiographic findings indicated that defect filling gradually increased over time and that smaller defects were covered with a greater amount of radiopaque substance. Bony islands were observed at 8 weeks at the center of the defect in both histologic sections and radiographs. Histometrical values show that it was impossible to determine the precise CSD of the rabbit cranium. However, the innate healing capacity that originates from the defect margin was found to be constant regardless of the defect size. CONCLUSIONS: The results obtained for the spontaneous healing capacity of rabbit cranial defects over time and the underlying factors may provide useful guidelines for the development of a rabbit cranial model for in vivo investigations of new bone materials.
Animals ; Islands ; Rabbits ; Research Design ; Skull ; Wound Healing

PURPOSE: We report our experience with a case of a nodular lesion of the lower palpebral conjunctiva with histologic features consistent with mucoepidermoid carcinoma. METHODS: A 72 year-old man presented with a left lower palpebral conjunctiva lesion. 3 x 3 mm sized flat pedunculated yellowish red mass was observed. Incisional biopsy proved the mass a mucoepidermoid carcinoma and wide local resection was conducted. RESULTS: Hematoxylin and eosin-stained sections showed lobules of tumor cells, consisting of predominantly epidermoid cells and scattered islands of mucin-secreting cells. Mucicarmine-stained sections demonstrated strong positivity, consistent with the diagnosis of mucoepidermoid carcinoma. CONCLUSIONS: In any case presenting palpebral conjunctival lesion, mucoepidermoid carcinoma should be differentiated, and it is necessary to confirm the diagnosis through biopsy.
Aged ; Biopsy ; Carcinoma, Mucoepidermoid* ; Conjunctiva* ; Diagnosis ; Hematoxylin ; Humans ; Islands

Cylindroma is an adnexal tumor which is mostly observed on the scalp. It usually occurs as a solitary lesion rather than multiple lesions. Histopathologically, the tumor is composed of numerous islands of basaloid cells which fit together like pieces of a jigsaw puzzle with surrounding hyaline sheaths. In Korea, there have been two reports of solitary cylindroma in the dermatologic literature, but no report of multiple cylindromas. We herein report a case of multiple cylindromas. A 34-year-old woman presented with three erythematous papules on her scalp, which developed four to five years before. Histopathologic findings on all papules revealed the typical appearance of cylindroma.
Adult ; Carcinoma, Adenoid Cystic* ; Female ; Humans ; Hyalin ; Islands ; Korea ; Scalp

Multiple trichoepithelioma is an uncommon skin disease with autosomal dominant transmission. A 21-year-old female ahd asymptomatic, flesh-colored, firm papules and nodules on the face, chest and back. Histopathologic examination showed multiple horn cysts and tumor islands composed of basaloid cells.
Animals ; Female ; Horns ; Humans ; Islands ; Skin Diseases ; Thorax ; Young Adult