We retrospectively investigated the prevalence of influenza virus type A infection and the efficacy of Kampo medicine as a prophylactic for handicapped residents at our social welfare institution, during the 2004/5 flu season. Upon studying a nationwide surveillance report for said season, we supposed that it had been difficult to prevent mass infection at our welfare institution with the usual preventive methods, because type B had prevailed for most of the season, and because of the differing type A (AH 3) antigenicity which prevailed late-season, for which there were no type A vaccines.43 of 90 (47.8%) residents given flu vaccinations twice, and 25 of 110 (22.7%) of staff members given flu vaccinations once contracted type A influenza between March and May of 2005. Interestingly, residents who had been administered Hozai for either short-term health problems or chronic disease, demonstrated a low influenza prevalence, there being a statistically significant difference (p<0.05) between our “Hozai” and “non-Hozai” groups. Furthermore Juzentaihoto, known to enhance immune function, seemed beneficial because of its low associated morbidity rate, and only 2 of 8 residents administered it contracted flu. No difference was observed, however, between generalized “Kampo treatment” and “non-Kampo treatment” groups.We consider that certain Kampo medicines may be useful for the prevention of influenza infection, in institutionalized handicapped residents with short-term health problems. Immunological enhancements, and the influence of Hozai are discussed here.
Medicine, Kampo ; Seasons ; Infection as complication of medical care ; Influenza ; Prophylactic

Filariasis, a parasitic infection endemic in parts of India, Myanmar, islands of the South Pacific, West and East Africa and Saudi Arabia can be diagnosed from various types of cytopathological specimens. This case documents the detection of filarial infection from hydrocele fluid cytology in a 30-year-old Myanmar migrant worker in Malaysia.
Liquid substance ; Cellular aspects of ; Infection as complication of medical care ; Microfilaria ; Myanmar

The effects of Enterovirus 71 (HEV71) infection on African green monkey kidney cells (Vero) were investigated. It was found that the infected cells showed progressive cellular morphological changes characteristic in apoptotic cells within 10 hours post-infection. The number of apoptotic cells correlated significantly with the number of HEV71 antigen positive cells when cells were labeled using terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick-end labeling (TUNEL) and stained for HEV71 antigen. Approximately 11, 26, 45 and 50% of the infected cells were apoptotic at 12, 24, 48 and 72 hours post-infection, respectively. Internucleosomal DNA fragmentation, characteristic in the late stage of apoptosis was noted beginning on day 2 post-infection. The DNA fragmentation, however, was absent in cells treated with the heat- and ultraviolet light-inactivated virus inocula. These results demonstrate the capacity of HEV71 to induce apoptosis in the infected cells. The induction, however, requires high level of HEV71 infectivity and the presence of live virus particles, suggesting the need for the presence of specific viral proteins for apoptosis to occur.
Infection as complication of medical care ; Apoptosis ; seconds ; Enterovirus ; Hour

parasitic ; Infection as complication of medical care ; Gays ; Syndrome ; Male population group

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus which causes epidemic fever, rash and polyarthralgia in Africa and Asia. Two outbreaks have been reported in Malaysia, in Klang, Selangor (1998) and Bagan Panchor, Perak (2006). It is not known if the outbreaks were caused by the recent introduction of CHIKV, or if the virus was already circulating in Malaysia. Seroprevalence studies from the 1960s suggested previous disease activity in certain parts of the country. In Asia, CHIKV is thought to be transmitted by the same mosquitoes as dengue, Aedes aegypti and Ae. albopictus. Due to similarities in clinical presentation with dengue, limited awareness, and a lack of laboratory diagnostic capability, CHIKV is probably often underdiagnosed or misdiagnosed as dengue. Treatment is supportive. The prognosis is generally good, although some patients experience chronic arthritis. With no vaccine or antiviral available, prevention and control depends on surveillance, early identification of outbreaks, and vector control. CHIKV should be borne in mind in sporadic cases, and in patients epidemiologically linked to ongoing local or international outbreaks or endemic areas.
increasing incidence ; Dengue ; Chikungunya virus ; Infection as complication of medical care ; control

Hepatitis A, an acute usually self limiting infection of the liver is one of the most common vaccine-preventable infectious disease in the world. Effective vaccines which provide long term immunity against hepatitis A have been available since 1992. They are of known good quality, well tolerated with no serious adverse events and have been successfully used to protect different populations from infection as well as interrupt outbreak in closed communities. Mathematical models estimate the long term persistence of antiHAV antibodies to be more than 25 years. Vaccination efforts should be supplemented by health education and improved sanitation. Planning for large scale immunization programmes against hepatitis A should take into consideration epidemiological and cost benefit studies.
Hepatitis A ; seconds ; Infection as complication of medical care ; Hepatitis A Vaccines ; Vaccines

A survey on intestinal parasitic infections and some risk factors of infection (social, economic and behavioral) was conducted in suburban area at Simum subdistrict, Mueang district, Nakhon Ratchasima Province during the period of April 3rd to April 11th, 2007. A total of 214 stool samples, from 85 males and 129 females were examined using simple direct smear, Kato's thick smear and modified Harada-Mori Filter Paper Strip culture technique. The results showed that the prevalence rate of protozoa infections by simple direct smear method was 17.3% (37 infected samples) in 11 males and 26 females and were from all age groups. Mixed infections (56.8%), showed higher results than single infection. The highest number of intestinal protozoan infections was Entamoeba histolytica (11.7%), followed by Blastocystis hominis (5.6%). Fifty four percent of protozoan infection was at a moderate to high level. Ninety five percent of infected cases consumed unboiled water. The prevalence rate of helminthic infections was 7% total by Kato's thick smear and Modified Harada-Mori Filter Paper Strip culture technique. Kato's Thick smear Technique showed the highest rate of Strongyloides stercolaris (2.8%), followed by hookworm infection (1.4%) Taenia spp. (0.9%), and Enterobius vermicularis (0.5%), respectively. All infections showed a light intensity, (< 200 epg), using Kato-Katz thick smear. Although Modified Harada-Mori's culture Technique showed higher S. stercolaris (3.3%) and hookworm infection (2.3%) than Kato's thick smear in the area where there is low Soil transmitted helminthes, we recommend using Simple or Kato's thick smear to determine the prevalence of parasitic infection due to these techniques being able to detect various groups of parasites, and being inexpensive and less time consuming.
seconds ; Kato ; Infection as complication of medical care ; parasitic ; suburban area

In 2006 there was a multiple outbreak of infectious gastroenteritis due to norovirus in health care facilities, old age nursing homes and other facilities in Hiroshima Prefecture. Also at JA Yoshida General Hospital during the period from October 3 to 17, 2006, symptoms of vomiting and diarrhea were observed in a total of 47 people including 29 in-patients in three out of six wards and 18 hospital staff members.This was reported to the public health center and an emergency meeting of the Infection Control Committee was convened. Under the guidance of the Public Health Center, the Infection Control Team (ICT) immediately had a good control over the situation, took infection preventive measures, informed patients of what had happened, and restricted hospital admissions and hospital visits. The number of new patients dropped to zero on October 17.After re-examining the gastroenteritis outbreak, the ICT reviewed the existing manual and prepared a new operation manual to cope withe future outbreaks of infectious gastroenteritis, including emergency measures to be taken, staff assignments, and improvement of the hospital environment. The ICT considers that there is a need for disseminating knowledge regarding measures against the infection and for making preparations for the future as a vanguard.
Hospitals ; Gastroenteritis ; seconds ; Infectious gastroenteritis, NOS ; Infection as complication of medical care

A new edition of infection control manual was brought out after months of reviewing the utility of the preceding edition. Using the new manual, a series of study meetings were held with the aim of raising awareness among the personnel of infection prevention.Preventive measures have been changing with rapid advances in medical treatment. The old manual, which had undergone revision repeatedly, was not utilized fully. In view of the situation, questionnaires were distributed to all the members of the hospital staff (n=447) to investigate the reasons why the manual had not been utilized. Although many respondents were of the opinion that the old manual was out of date, too thick, and unreadable, 44.7% said they had used it. 55.3% answered that they had asked their superiors or colleagues out of necessity. Based on these results, we started making a compilation of a new manual, easy to understand and friendly to the users. It took about six months to complete it. Copies of the new manual were given to all the staff members. In the study meetings, various subjects were taken up for discussion, including the definition of nosocominal infection, “universal precaution,” how to effectively wash your hands, how to keep the rest rooms clean, how to wear the gloves and mask, and so forth. We believe that the personnel’s consciousness of infection prevention was further raised by holding the study meetings.
Manuals ; Prevention ; Infection as complication of medical care ; Hospitals ; Infections of musculoskeletal system

For severe acute respiratory syndrome (SARS), methodologies are yet to be established for prompt diagnostic testing, treatment and prevention by means of vaccination. Such being the situation, it is necessary to implement stringent measures in preventing the transmission of this infectious disease based on a correct understanding of its epidemiological characteristics. The pathways of transmission are by droplet and by contact. Risk factors include social contacts with SARS cases within a radius of 2 meters or household contacts, badly ventilated rooms, touching contaminated objects and surfaces, exposure to body fluids. The major clinical symptoms of the acute respiratory disease include, like influenza, fever, chill, tiredness (malaise), muscle aches, trepidation, nausea and headache. Compared with patients who contract influenza, SARS patients often had dyspnea and diarrhea, but rarely complain of pharyngalgia and pituita. A close correlation has been noted between the stage of SARS and its infectivity, capability. During the incubation period, which lasts 2 to 10 days, the disease is asymptomatic and reportedly almost no infectious. But there is general agreement among experts that SARS becomes highly infectious when it enters the lower airway infection period and begins to produce such symptoms as fever and dry cough, dyspnea.As the main points of the measures to prevent SARS from spreading, we would like to refer to triage and prevention of cross infection. A triage system should be adopted as the need arises. Under the system, patients suspected to have SARS are separated from other patients and given priority in medical treatment. Standard precautions should not be forgotten. The use of alcohol-based hand rubs and the wearig of surgical masks are effective means to cut off the route of infection. These efforts would make it possible to effectively prevent the infectious diseases like SARS from being spread form person to person and thus protect the public from the pandemic.
Infection as complication of medical care ; Prevention ; symptoms <1> ; strategy ; seconds