No abstract available.
Immunosuppression*

No abstract available.
Humans ; Immunosuppression ; Mycobacterium chelonae*

Multiple dermatofibromas are rare and their etiology is unknown. An association with immunosuppression or altered immunity including autoimmune disorders has been reported. The mechanism for the development of multiple eruptive dermatofibromas in the setting of immune disturbance remains unclear. We herein report four cases of multiple dermatofibromas, one of them is associated with immunosuppression.
Histiocytoma, Benign Fibrous* ; Immunosuppression

No abstract available.
Immunosuppression* ; Prognosis* ; Transplantation*

Infection-induced panniculitis develops either through direct inoculation or as a manifestation of sepsis. However, it has rarely been considered as a disease entity within broader context of panniculitis. Moreover, panniculitis associated with a cardiac abscess without the evidence of sepsis has not been reported. We describe a case of infection-induced panniculitis associated with a cardiac abscess. We suggest that infection should be considered as a potentially important etiology of panniculitis, especially in the case of immunosuppression, and in such a case, meticulous efforts should be done to find the focus of infection.
Abscess* ; Immunosuppression ; Panniculitis* ; Sepsis

No abstract available.
Immunosuppression* ; Liver Transplantation* ; Liver*

Collapsing Glomerulopathy (CG) is a rare entity presenting as nephrotic syndrome and rapidly progressive renal deterioration. It has been first identified among African-American patients and subsequently dubbed HIV-associated nephropathy after a number of patients with HIV were found to have CG. It has re-emerged recently among patients with COVID-19. To our knowledge, this is the first case of primary collapsing glomerulopathy in the country to be published. The case is a 36-year-old Filipino female admitted due to bipedal edema which started 2 weeks post-partum. She has no comorbidities and social history was negative for illicit drug use. Initial work up showed hypoalbuminemia and diffuse hepatic disease on ultrasound. She was referred to a gastroenterologist where albumin infusion and paracentesis was done but with no improvement. She developed anasarca and was admitted. Paracentesis obtained minimal ascitic fluid. Serum ascites albumin gradient was low and baseline laboratories showed high creatinine, hypoalbuminemia, and albuminuria. 24-hour urine protein was 11 grams, ANA and anti-DsDNA were negative and c3 and c4 levels were normal. Hepatitis profile was negative for infection. Abdominal CT scan revealed multiple hypoenhancing lesions. Tumor markers CA-125, CA 19-9 and CA 15-3 were high. Breast ultrasound showed simple breast cyst. Gynecology consult was called where pap smear was negative for atypical cells. Surgery service recommended monitoring for the pancreatic and breast lesions. Kidney biopsy was delayed due to new onset bacterial pneumonia. COVID-19 RT-PCR test was negative. Patient was discharged improved with no edema. On follow up, the kidney biopsy result came out to be collapsing glomerulopathy. HIV test was then done and was negative. Bipedal edema and albuminuria recurred. She was started on tacrolimus. She has been on regular follow up and currently has no edema, no proteinuria and normal creatinine level. This is an interesting case as the primary glomerular disease has been masked by the earlier laboratory findings which led us to think of liver disease then a paraneoplastic nephrotic syndrome. Ultimately, the renal biopsy revealed the diagnosis. This serves as an index case for primary collapsing glomerulopathy in a Filipino patient on remission after being treated with tacrolimus.
Nephrotic Syndrome ; Immunosuppression Therapy

There were 39 aplastic anemia patients with immunopathology, who was treated by immunosuppresion such as: Spleenectomy, thymus transplantation using cyclosporine A. The results show that: immunosuppression has successful rate of 50-60% in aplastic anemia after internal treatment was not effectiveness.
Bone Marrow Diseases ; Immunosuppression ; Therapeutics

The scientific name of Morinda citrifolia is Morinda citrifolia L., with its family Rubiaceae. Morinda citrifolia was used by the people for hypotensive drugs, medications to enhance the resistance of the body. Many studies have been proved the effects on immuno-stimulation of total root of Morinda citrifolia in vitro, in vivo and in clinic for a long time. Fruit extract of Morinda citrifolia given to mice after being treated with 100rad x 6 days at oral daily dose of 6 gram/kg bogy weight in 9 consecutive days increased the relative weights of spleen and thymus, total leukocyte count, number of lymphocytes, natural killers and monocytes, rates of immune rosette forming and platelet forming cells and dermoreaction with OA antigen as compared with the control group
Fruit ; Morinda ; Animals ; Immunosuppression ; radiation

The immune response to any stimulus is complex, requiring coordinated action by several types of cells in a tightly regulated sequence. Thus, a physical stress such as exercise may act at any number of points in the complex sequence of events collectively termed the immune response. Although exercise causes many propound changes in parameters of immune function, the nature and magnitude of such changes rely on several factors including the immune parameters of interest; type, intensity, and duration of exercise; fitness level or exercise history of the subject; environmental factors such as ambient temperature and humidity. Although regular moderate exercise appears to be important factor for increasing immunity, Athletes are susceptible to illness, in particular upper respiratory track infection, during periods of intense training and after competition. In addition, in elite athletes, frequent illness is associated with overtraining syndrome, a neuroendocrine disorder resulting from excessive training. Through this paper, we want to investigate the effects of exercise on the immunosuppression such as exercise induced lymphopenia, asthma, anaphylaxis, URT (upper respiratory track), and TB (tuberculosis) infection. and also, we want to suggest a direct mechanism, protection and therapy of exercise induced immunosuppression.
Anaphylaxis ; Asthma ; Athletes ; Humans ; Humidity ; Immunosuppression ; Lymphopenia