1.The effect of radiation therapy on cellular immune response in patients with squamous cell lung carcinoma.
Soo Taek UH ; Chul Hyun KIM ; Yeon Tae CHUNG ; Yong Hun KIM ; Choon Sik PARK ; Hi Bahl LEE ; Seung Jae HUH
Tuberculosis and Respiratory Diseases 1991;38(1):25-33
No abstract available.
Humans
;
Immunity, Cellular*
;
Lung*
2.Genetic marker and cellular immune response of Behcet's disease.
Kyung Sook PARK ; Ho Youn KIM ; Dong Jun PARK
Korean Journal of Immunology 1991;13(1):99-104
No abstract available.
Genetic Markers*
;
Immunity, Cellular*
3.Advances in methodologies for evaluating cell-mediated immune responses.
Zhanhao LU ; Rui LUO ; Tao WANG ; Dailang ZHONG ; Hua-Ji QIU ; Yuan SUN
Chinese Journal of Biotechnology 2023;39(12):4759-4772
Cell-mediated immune response is an important part of machinery in maintaining the body's homeostasis. After the innate immune system selectively activates the adaptive immune system, the cell-mediated immunity exerts its killing and clearance functions. Therefore, evaluating the level of cell-mediated immune response is crucial in the diagnosis and treatment of cancer, monitoring the immune status after organ transplantation, diagnosing and preventing viral diseases, and evaluating the effectiveness of vaccines and other areas. From the initial overall assessment of the immune effects in vivo to the precise detection of the number and function of multiple immune cells, the evaluation methods of cell-mediated immune response have greatly advanced. However, cell-mediated immune response involves multiple levels in the body, and it's difficult to choose the numerous detection methods available. The article systematically compares the evaluation methods of cell-mediated immune response at four different levels: the organism, the tissue and organ, the immune cells and the immune molecules, with the aim to facilitate the applications of related technologies.
Humans
;
Immunity, Cellular
;
Neoplasms/therapy*
;
Immunity, Innate
4.Clinical significance of cellular immunity in the renal interstitium of IgA nephropathy.
Tae See CHUNG ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1991;10(2):157-165
No abstract available.
Glomerulonephritis, IGA*
;
Immunity, Cellular*
;
Immunoglobulin A*
5.Clinical significance of cellular immunity in the renal interstitium of IgA nephropathy.
Tae See CHUNG ; Young Joo KWON ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1991;10(2):157-165
No abstract available.
Glomerulonephritis, IGA*
;
Immunity, Cellular*
;
Immunoglobulin A*
6.NO2- and ATP synthesis in the EMT-6 cell stimulated by mercury chloride.
Gyung Jae OH ; Dai Ha KOH ; Jung Ho YOUM
Korean Journal of Preventive Medicine 1996;29(3):495-506
Effect of Mercury chloride on the synthesis of NO2- and ATP were observed in EMT-6 cells which were culture with cytokines(IL-1alpha and IFN-gamma) and various concentrations of mercury chloride from 0.05 to 0.08 M. Viability of EMT-6 cells were observed above 90% in almost groups. There were not significant differences in the viability between mercury supplemented groups and control group. It suggests viability of EMT-6 cells were not influenced by these concentrations of mercury chloride. Results of the synthesis of nitrite showed significant time and group effect. There is a significant interaction effect between concentration of mercury chloride and culture time. The effect of various concentration of mercury chloride is not the same for all levels of culture time. There were significant differences in the synthesis of nitrite between mercury chloride supplemented groups and control group, and the synthesis of nitrite in EMT-6 cell by the supplement of mercury chloride was significantly decreased in a dose-dependent manner. Results of the synthesis of ATP showed a significant group effect, and the time main effect and the Group x Time interaction were also significant. There were significant differences in the synthesis of ATP between mercury chloride supplemented groups and control group, and the synthesis of ATP in EMT-6 cell by the supplement of mercury chloride was significantly decreased in a dose-dependent manner. These results suggest that the disorder of cell mediated immunity by mercury chloride could be related to the inhibition of nitric oxide synthesis which will be caused by the decreased synthesis of ATP.
Adenosine Triphosphate*
;
Immunity, Cellular
;
Nitric Oxide
7.Immune Cells (T Cell, T Subsets and B Cell) in the Peripheral Blood of Patients with Psoriasis and Effects of Photochemotherapy (PUVA) on These Cells.
Choong Rim HAW ; Young Chul JUNG ; Eul Nam HAN ; Soo Duk LIM ; Ki Bum MYUNG ; Hong Il KOOK
Korean Journal of Dermatology 1983;21(5):513-520
Recent studies have demonstrated that the patients with psoriasis have various immune alternation in both humoral and cellular immunities. However the results of these are still controversial. These facts promoted us to analyze the immune cells (T cell, T subsets and B cell) by rosette method for these cells in peripheral blood of 15 patients with psoriasis. And we also analyzed the effects of photo- chemotherapy(PUVA) on these cells. The results were summerized as follows; 1. The mean values of T cell, T, T, cell and B cell in peripheral blood of the- patients with psoriasis before PUVA therapy were 56. 2+-5.7%, 35.1+-6.9%, 5. 5+l.4%, 11.6+4. 0% respectively, These results of immune cells showed signi- ficantly lower mean values when these were compaired with the mean values. of nomnal control group(T cell; 65. 2+-2.9%, TM cell; 45.8+-3.2%, T cell; 7.3+ 1.3% B cell; 16.2+2.4%), respectively (T cell, Tm Tg, p<0.01, B cell; p<0.05). 2. The mean values of T cell, T, T, cell and B cell in peripheral blood (countinue..)
Humans
;
Immunity, Cellular
;
Photochemotherapy*
;
Psoriasis*
;
PUVA Therapy
8.The effects of RU 41.740, a glycoprotein extract from klebsiella pneumoniae, on peripheral blood mononuclear cells.
Moon Kyu KIM ; Dong Soo KIM ; Hyun Ok KIM
Journal of the Korean Pediatric Society 1992;35(8):1066-1072
No abstract available.
Glycoproteins*
;
Immunity, Cellular
;
Klebsiella pneumoniae*
;
Klebsiella*
9.Regulation of cellular immunity in cryptococcosis III. induction ofcryptococcus neoformans-specific T cells and hybridoma.
Tai You HA ; Young Min PARK ; Yoon Kyu PARK ; Hern Ku LEE ; Chong Wook PARK
Korean Journal of Immunology 1992;14(1):15-23
No abstract available.
Cryptococcosis*
;
Hybridomas*
;
Immunity, Cellular*
;
T-Lymphocytes*
10.Regulation of cellular immunity in cryptococcosis III. induction ofcryptococcus neoformans-specific T cells and hybridoma.
Tai You HA ; Young Min PARK ; Yoon Kyu PARK ; Hern Ku LEE ; Chong Wook PARK
Korean Journal of Immunology 1992;14(1):15-23
No abstract available.
Cryptococcosis*
;
Hybridomas*
;
Immunity, Cellular*
;
T-Lymphocytes*