1.Causes of delayed presentation in patients with diabetic septic foot: a short prospective case series study at Nonga General Hospital
Papua New Guinea medical journal 2019;62(1-2):46-49
Surgical services in Papua New Guinea (PNG) have seen an increase in admissions of patients with diabetic septic foot (DSF). Perception and beliefs about the causes of foot ulcer in PNG differ from medical evidence and may play a role in foot-related behaviours among DSF patients. This hospital-based prospective case series study examined the reasons for late presentation among 30 DSF patients in Nonga General Hospital from October 2013 to October 2014. Belief in sorcery was the most common cause of late presentation. Those who chose more than one home treatment were the most likely to present late, and those who presented late had a higher chance of getting a lower extremity amputation than those who presented early.
2.The management of spine pathology in Papua New Guinea.
W Matui Kaptigau ; Perista Mamadi ; Ikau Kevau
Papua and New Guinea medical journal 2007;50(1-2):87-90
This paper outlines the principles of the management of different spinal diseases. In Port Moresby General Hospital between 2004 and 2006 there were 41 spinal injuries, 36 cases of spinal tuberculosis (8 of whom were operated on), 3 non-tuberculous infections and 11 degenerative conditions. The incidence of spinal dysraphism is low in Papua New Guinea with only 5 cases recorded in Port Moresby over the 3-year period. Identification and assessment of spinal pathology were sometimes limited by a lack of radiological investigation and often the resources were not available for optimal treatment. 8 cases with myelopathy had no definitive diagnosis made.
Pathology processes
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Papua New Guinea
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Mores
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Port - alcoholic beverage
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Vertebral column
3.The role of surgery and oral methotrexate treatment on lower lip squamous cell carcinoma in Milne Bay Province and National Capital District, Papua New Guinea
Kennedy James ; Ikau Kevau ; Westin Seta
Papua New Guinea medical journal 2018;61(1-4):50-58
This cohort study was undertaken over 54 months to observe the effectiveness of primary surgery and long-term oral methotrexate (MXT) treatment on lower lip squamous cell carcinoma (SCC) in Milne Bay Province and National Capital District, Papua New Guinea (PNG). The current standard treatment for lower lip SCC depends on the stage of the disease: stage 1 is treated with either surgery or radiotherapy only, while stages 2 and 3 are treated with surgery followed by chemotherapy and radiotherapy; stage 4 is metastatic disease and is treated with palliative chemotherapy and radiotherapy. Due to limited treatment options available in Papua New Guinea for cancer patients, this study was conducted with the primary aim of finding an alternative, affordable and effective treatment option for lower lip SCC in our setting. There were 20 patients recruited in the study with histologically confirmed SCC of the lower lip. They had primary surgeries which included selective neck dissection (SND) for positive neck involvement (stages 2, 3 and 4) (8; 40%) and tumour resection and reconstruction (20; 100%), and, once the wounds had healed well, they were commenced on long-term oral MXT treatment for 24 months. The follow-up period was approximately 54 months and the results of the primary outcomes measured were: no local recurrence, no neck metastasis, no distant metastasis and no mortality. In conclusion, even though we acknowledge the small number of subjects recruited, this cohort study does give some hope to health care practitioners, including surgeons, in PNG that lower lip SCC can be alternatively treated with surgery and methotrexate when there are no other treatment modalities available in their health facility.
4.Factors associated with lower extremity amputation in patients presenting with diabetic septic foot: a prospective case series
Jackson Goru Nuli ; Caleb Breria ; Kevin Lapu ; Ikau Kevau
Papua New Guinea medical journal 2016;59(3-4):187-190
The rapid demographic changes occurring in the Pacific island countries, including Papua New Guinea, have led to a rapid increase in the prevalence of non-communicable diseases. Surgical services in Papua New Guinea are seeing a marked increase in admissions for diabetic septic foot (DSF). Lower extremity amputation is common, although specific criteria for this procedure are lacking. We report a prospective case series of 20 patients admitted to the Surgical Ward of Nonga General Hospital with DSF from October 2013 to July 2014. Patients who had lower extremity amputation were younger, had a higher level of HbA1c and a higher Wagner ulcer score than those managed conservatively.
5.The bacterial flora of acute appendicitis at the Port Moresby General Hospital in Papua New Guinea.
Hasola, Damien J ; Dutta, Ray ; Darrell, Cecil ; Gende, George ; Kaptigau, William ; Liko, Osborne ; Kevau, Ikau
Papua and New Guinea medical journal 2012;55(1-4):12-5
Acute appendicitis is a common cause of acute abdomen requiring an emergency appendicectomy. Complications such as perforation and peritoneal contamination leading to peritonitis can result from delay in presentation and an emergency operation. This study prospectively recruited 101 patients diagnosed with acute appendicitis to correlate the bacterial flora with the severity of appendicitis. The results show that 90 patients had acutely inflamed or gangrenous appendicitis and 11 had perforated appendicitis. The ages ranged from 6 to 49 years with a median of 20 years. There were 59 females and 42 males. The commonest isolates were aerobic bacteria such as Escherichia coli, Group D streptococci and Klebsiella pneumoniae. Mixed infection with anaerobes such as Bacteroides fragilis was seen only in perforated appendicitis. The best choices of antibiotic were a fluoroquinolone, cephalosporin and aminoglycoside for aerobic organisms and metronidazole for anaerobes.
6.Diabetic foot ulcers in Port Moresby General Hospital 2003-2008: review of the principles of effective prevention and management of diabetic foot.
Kuzma, Jerzy ; Hasola, Damien J ; Lino, Tom ; Liko, Osborne ; Waine, Arnold ; Kevau, Ikau
Papua and New Guinea medical journal 2012;55(1-4):61-6
In the recent decade in Papua New Guinea and other Pacific countries there has been an increasing trend of lifestyle diseases, including obesity associated with diabetes mellitus. Foot ulceration and infection leading to amputation are common and feared complications of diabetes. Yet these are potentially the most preventable of all complications in diabetic patients. Several studies have shown that half of all diabetic foot ulcers can be prevented by education and simple foot care. The primary goal of this study was to depict the scale of the diabetic foot as a community health problem. The secondary goal was to review the current literature on diabetic foot in order to develop a more effective preventive strategy.
7.Randomized clinical trial to compare a single dose with 3 doses of prophylactic antibiotic in open reduction and internal fixation of the fractures of long bones
Papua New Guinea medical journal 2015;58(1-4):28-35
To reduce the incidence of surgical site infection (SSI), perioperative antimicrobial
prophylaxis has long been advocated for joint replacement and open reduction with
internal fixation of long bones. Increasing health care costs have focused hospital interest
on more cost-effective procedures. Although current literature indicates that single-dose
antibiotic prophylaxis is comparable to a 3-dose regimen, there are no reports from lowincome
countries. The primary aim of this study was to compare the infection rate following
open reduction and internal fixation of long-bone fractures in groups with a single dose
and 3 doses of prophylactic antibiotic. The secondary aim was to compare the costeffectiveness
of both antibiotic regimens. This is a prospective randomized clinical trial
(RCT) to compare the incidence of surgical site infection between the patients allocated
randomly into two groups with different antibiotic prophylactic regimens: single dose or
3 doses 8 hourly of 1g ceftriaxone administered intravenously. 200 consecutive patients
who underwent open reduction and internal fixation (ORIF) for closed long-bone fractures
were enrolled in this study. The rate of postoperative SSI was 4.1% in the single-dose
group and 2.2% in the 3-dose group; the overall SSI rate was 3.2%. The primary endpoint
of this study, which is the incidence of SSI, showed no significant difference between
the single-dose and 3-dose prophylactic antibiotic groups. Furthermore, there was no
difference between groups regarding the length of hospital stay. Our randomized clinical
trial affirmed that single-dose antibiotic prophylaxis in orthopaedic clean operations is
not only a cost-saving practice but also is effective for SSI prevention, and should be
incorporated in the development of clinical practice guidelines in tropical hospitals.
Clinical Trials as Topic- statistics &
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numerical data,
8.Gastroschisis management without a neonatal intensive care unit and total parenteral nutritional support
Jack Mulu ; Okti Poki ; Ikau Kevau ; Noah Tapaua ; Mclee Matthew ; Annett Jacobsen ; Amos Low
Papua New Guinea medical journal 2015;58(1-4):83-88
In the absence of a neonatal intensive care unit (NICU) and total parenteral nutrition (TPN) gastroschisis management is challenging (1). If surgical closure is not done within the first 6 hours post partum, impending complications intervene, which then prevent a good outcome in such infants. The defect near the right side of the umbilicus provides the avenue for the intra-abdominal contents to protrude into the amniotic cavity in intra-uterine life and visceral exposure to the external environment increases the morbidity after delivery. The tight 2.5-5 cm bottleneck diameter provides further complications if not surgically corrected immediately. The prognosis has improved over the years and in well-set-up hospitals more than 95% have survived. Appropriate antenatal diagnosis (2) and early neonatal surgical intervention have improved the survival of these neonates. Blood investigation to assist with the antenatal diagnosis, such as amniotic fluid beta-endorphin analysis (3) and alpha-fetoprotein, assists in anticipating severe complications. Prevention of complications such as mesenteric infarct, fluid and electrolyte imbalance, necrotizing enterocolitis (NEC) and raised intra-abdominal compartment syndrome (RIACS) (2) and providing nutritional support have resulted in the good outcome of these cases. In the absence of accurate radiological diagnosis and back-up support services such as NICU and TPN, it is challenging to manage such infants. In a country where subspecialties are lacking it is very difficult to reassure the parents of a gastroschisis patient. Most of them do not make it. The following two case reports highlight some of these limitations and the alternative measures that can be taken to address the issues.