Background: Idiopathic nephrotic syndrome is not uncommon in children. The disease affects children's physical development. Idiopathic nephrotic syndrome cause many complication in which effecting to physical development has been influenced much to their life, study and living activities of children. Objectives:This study aims to learn about the physical development and to find some factors impacting on physical development ofchildren with idiopathic nephrotic syndrome. Subjects and method: A prospective and descriptive study was conducted on 100 patients diagnosed with idiopathic nephrotic syndrome disease who have been followed up for from 1 year to 6 years in that duration since September 2006 to March 2007. Results:Height standard deviation score (SDS) was less than -2 SO in 15.0% patients. Six per cent of patients had weight SDS ofless than 250. Delayed puberty was seen in 21.6% patients. Some factors impacting on physical developmentwere duration of the disease, relapses, nephrtitis-nephrotic syndrome, prolonged corticoid treatment. Conclusion:Idiopathic nephrotic syndrome retarded physical development and puberty in children. It should be considered careful before indicate to use corticoid because using corticoid for a long period will effect to the height development of children.
Nephrotic Syndrome/ pathology ; therapy ; Idiopathic minimal change nephrotic syndrome ; Child