2.The significance of somatosensory evoked potential test in peripheral nerve injury.
Tai Ryoon HAN ; Jin Ho KIM ; Hyeon Sook KIM
Journal of the Korean Academy of Rehabilitation Medicine 1991;15(3):287-294
No abstract available.
Evoked Potentials, Somatosensory*
;
Peripheral Nerve Injuries*
;
Peripheral Nerves*
4.Expression of Cellular Oncogenes in Colorectal Cancer : c-myc, c-Ha-ras and c-erbB-2.
Hae Hyeon SUH ; Keun Nam SHIN ; Young Jin KIM
Journal of the Korean Surgical Society 1998;54(Suppl):983-990
Although causative factors are not completely defined, carcinogenesis of colorectal cancer is attributed to multiple genetic alterations. The abnormal expressions of oncogenes are regarded to be responsible for the production of malignant phenotype, subsequent invasion and metastasis. From 63 surgically resectable colorectal adenocarcinoma patients, expression of oncogenes in colorectal cancer tissue was evaluated with immunohistochemical staining methods using monoclonal antibodies to products of the oncogenes. To evaluate the possibility of oncogenes as a prognostic factor, we studied the relationship between the expression of oncogenes and the clinicopathologic findings which are well known prognostic factors. Rates of expression in colorectal cancer tissue were 27% for c-myc, 74.6% for c-Ha-ras and 77.8% for c-erbB-2 oncogenes. The positive rate of c-erbB-2 oncogene was higher in the well differentiated group than in the poorly differentiated group. The rates of expression of c-myc and c-Ha-ras oncogenes were significantly correlated each other. Expression of these oncogenes in colorectal cancer were not correlated with the pathologic stage, location of cancer, DNA ploidy pattern and histologic differentiation except between c-erbB-2 and histologic differentiation. In conclusion, there seems to be a possibility that c-erbB-2 could be used as a prognostic factor of colorectal cancer. However, further and more intensive study seems to be required.
Adenocarcinoma
;
Antibodies, Monoclonal
;
Carcinogenesis
;
Colorectal Neoplasms*
;
DNA
;
Humans
;
Neoplasm Metastasis
;
Oncogenes*
;
Phenotype
;
Ploidies
5.MR Imaging of the Trachea:In Vivo and In Vitro Study.
Hyeon Joo JEONG ; Jin Suck SUH ; Myung Joon KIM
Journal of the Korean Radiological Society 1994;30(6):1051-1056
PURPOSE: To establish signal intensity characteristics of the trachea according to the histologic layers, we performed in vivo and in vitro MR studies. MATERIALS AND METHODS: We performed MR imaging of the trachea at 1.5T unit in 11 patients mediastinal masses, vascular anomalies, tracheal stenosis or iatrogenic tracheoesophageal fistula, aryepiglottic fold thickening or mass, tracheal carcinoid, one healthy volunteer and one cadaveric trachea. By using anterior, volume neck or 3 inch dual coil with various pulse sequences, axial and coronal images of the trachea were obtained. The tracheal layers with different signal intensity on MR images were correlated with the histology. RESULTS: In vivo and in vitro MR studies revealed two layers of the trachea ;the inner layer had intermediate to high signal and the outer had low signal. The tracheal cartilage showed low signal intensity in all pulse sequences. The submucosa appeared as intermediate signal intensity on T1 weighted images but high signal intersity on other images due to its abundant mucous and mucoserous glands. However, the mucosa and perichondrium could not be defined on MR images. CONCLUSION: Characterization of the signal intensity according to the histologic layers of the trachea might be helpful for the evaluation of intrinsic lesions of the irachea or the possibility of tracheal invasion from the adjacent tumors.
Cadaver
;
Carcinoid Tumor
;
Cartilage
;
Healthy Volunteers
;
Humans
;
Magnetic Resonance Imaging*
;
Mucous Membrane
;
Neck
;
Trachea
;
Tracheal Stenosis
;
Tracheoesophageal Fistula
6.A case of polymorphism reticulosis that showed eczematoid skin lesion.
Kye Wang WHANG ; Kyeong Joon HYEON ; Hong Jin KIM
Korean Journal of Dermatology 1991;29(2):261-266
A 34-year-old Korean man presented with a 3 week history of a yellowish eczema like patch on the left thigh. Sixteen months prior, he was diagnosed with polymorphie r eticulosis of the left nasal cavity. The patient, refuse<3 conventional radiation therapy and took herbal medication and diet therapy instead. Biopsy of the nasal cavity, hard palate and left thigh lesians showed extensive necrosis and polymorphic infiltrates of atypical lymphocytes with angiodestructive invasion. Irnmunohistochemical study of left thiyh lesion showed strong CD2 positivity con sistent with the diagnosis of peripheral T cell lymphorra.
Adult
;
Biopsy
;
Diagnosis
;
Diet Therapy
;
Eczema
;
Humans
;
Lymphocytes
;
Lymphoma, T-Cell, Peripheral
;
Nasal Cavity
;
Necrosis
;
Palate, Hard
;
Skin*
;
Thigh
7.A Case of Congenitla Pyloric Atresia.
Hyeon Jeong LEE ; Jun Hoe JEONG ; Gae Soon YEO ; Hee Jin KIM ; Chan Yung KIM ; Jun Hyeon KIM
Journal of the Korean Pediatric Society 1995;38(12):1713-1717
No abstract available.
8.Effect of Cyclosporine A on Plasma and Urine Levels of Endothelin-1 in Steroid Dependent Minimal Change Nephrotic Syndrome.
Pyung Kil KIM ; Ji Hong KIM ; Je Woo KIM ; Jin Sung LEE ; Hyeon Suk KIM
Journal of the Korean Society of Pediatric Nephrology 1998;2(1):20-25
A fine needle aspiration biopsy specimen of a retroperitoneal mass in a 26-year-old man who had had an orchiectomy for seminoma was submitted for cytologic evaluation. Cytologic features of the specimen included uniform neoplastic cells found singly or in groups of several cells intermingled with lymphocytes in a characteristic foamy, lacelike background. These cells varied from 10 to 20 m in diameter. The nuclei were round to ovoid with fine or reticular chromatin and one or more prominent nucleoli. The poorly defined cytoplasm stained pale-blue or blue with cytoplasmic vacuoles. The cytologic appearance was consistent with seminoma. Documented reports of the cytological appearance of seminoma are rare. The diagnosis of primary gonadal seminoma by fine needle aspiration biopsy is probably not indicated since the treatment of a primary gonadal tumor, regardless of its histogenesis, requires surgical resection. However, fine needle aspiration biopsy is extremely valuable in the diagnosis of extragonadal as well as metastic and recurrent seminoma.
Adult
;
Biopsy
;
Biopsy, Fine-Needle
;
Chromatin
;
Cyclosporine*
;
Cytoplasm
;
Diagnosis
;
Endothelin-1*
;
Gonads
;
Humans
;
Liver
;
Lymphocytes
;
Nephrosis, Lipoid*
;
Orchiectomy
;
Plasma*
;
Seminoma
;
Vacuoles
9.A Case of Crescentic Glomerulonephritis Superimposed on Membranous Glomerulonephropathy.
Baek Nam KIM ; Jin Won YOOK ; Ji Hong KIM ; Pyung Kil KIM ; Hyeon Joo JEONG
Journal of the Korean Society of Pediatric Nephrology 1999;3(1):95-99
Cytologic findings of pleural effusion in three cases of rhabdomyosarcoma are reported. Case 1 was a pleomorphic rhabdomyosarcoma which had devoped at the chest wall of an elderly male patient and caused pleural effusion. The cytologic features were consistent with pleomorphic rhabdomyosarcoma, that was, showing loose clusters, cellular pleomorphism, and abundant finely vesicular cytoplasm. Cases 2 and 3 were embryonal rhabdomyosarcomas in young adults. Primary site was the oral cavity in case 1, but unknown in case 2 and case 3. The effusion cytology was similar in these cases. Clustered or isolated small round cells with hyperchromatic nuclei and scanty cytoplasm were smeared. The cohesiveness of tumor cells was weak and the cells did not show linear arrangement or nuclear molding. Effusion cytology in a sarcoma patient would be diagnostic when the primary site and the type of sarcoma were already known.
Aged
;
Cytoplasm
;
Fungi
;
Glomerulonephritis*
;
Glomerulonephritis, Membranous*
;
Humans
;
Male
;
Mouth
;
Pleural Effusion
;
Rhabdomyosarcoma
;
Rhabdomyosarcoma, Embryonal
;
Sarcoma
;
Thoracic Wall
;
Young Adult