After chemoradiation therapy, tumor tissue metabolism changes earlier than its shape in advanced non-small cell lung cancr (NSCLC). Therefore, Positron emission tomography-computed tomography (PET-CT) can early assess the therapeutic efficacy and prognosis. But PET-CT might bring up some false negative or false positive outcome, while combined with the tumor markers, more accurate assessments of therapeutic efficiency and prognosis could be made for advanced(NSCLC).

Positron emission tomography (PET)/CT plays an important role in the diagnosis of bone metastasis from lung cancer,and can reflect the pathophysiological and morphological changes in lesion of bone metastasis.The sensitivity,specificity and the overall accuracy of PET-CT for the diagnosis of bone metastasis in patients with lung cancer are higher than those of routine methods such as X-ray,CT scan,MRI and SPECT/CT.