The study was carried out with healthy white mice of the strain of Swiss, weighed 202 g, fed properly in good supply of water and food. Results a pain relief and narcotic effects of the material. An intensive dose 200 times higher than usual clinical dose did not manifest toxicity in the animal
Medicine, Traditional ; Chemistry, Pharmaceutical ; Acute Toxicity Tests

Cau tich fluid extract was studied on white mice. The dose of 4 g/kg of body weigh exerts against acute inflammation and relief the pain 2 hours, 4 hours, and 6 hours after the onset of inflammation. On the experimental granuloma, Cau tich has a moderate effect on chronical inflammation. In experimental model of “hot plate” Cau tich manifests a pain relief effect centrally and peripherally
Inflammation ; Medicine, Traditional ; Chemistry, Pharmaceutical ; drugs

Fluorescence in Situ Hybridization (FISH) is cytogenetics - molecular technique. FISH is the rapid detection technique of chromosomal aberration by chromosome specific probes applied to interphase cells. In this study, the authors used Kit duple DNA probe for chromosome 13, 21, X, Y to prenatal diagnosis of Down’s syndrome. With 6 amniotic fluid samples, the authors obtained the results as follows: 2 samples were Down’s syndrome trisomy; 1 sample was Patau syndrome trisomy; 3 samples were normal; 1 sample male foetus died without clear causes. Cytogenetic result: 46, XX but FISH result: 46, XY; PCR (Polymerase Chain Reaction) result: TDF (Testis Determining Factor): (+). These results were confirmed by chrosome analysis.
Down Syndrome ; Prenatal Diagnosis

From 1990-2000, 1.282 cases with IPT, who diagnosed and treated, consist of 499 (38.9%) children and 783 (61.6%) adults at Blood Transfusion and Hematology Centre HCM city. Almost the patient were treated with corticoid (2mg/kg/body weight/day) protocol. Minority another patient were treated by gamma globulin. Results of corticoid therapy regimens on children were complete response: 77.8% partial response: 9%, dependent of corticoid: 2.5% and, no response: 10.7%, while the effect of this therapy in adults was low. Rate of persistent ITP after 6 months (chronic ITP) in children: 23.5%, in adults: 60%.
Purpura, Thrombocytopenic, Idiopathic ; Blood Transfusion ; Therapeutics

Healthy rats with weight of 120-180 g were randomly divided into 4 groups. They tested the anti-acute inflamatory activity of T1 (3 -methoxy 4 hydroxy-5 bromobenzylidien para bromo anilin) and T2 (3-methoxy 4 hydroxy-5 nitrobenzylidien p-nitro anilin). The results have shown that T1 had a significant antiinflamatory activity after 2 h and 4 h of the test but had no antiflamatory activity after 6 h of the test comparing with the control. While the anti-inflamatory activity of T2 was not different from this in the control. This study concluded that the anti-inflamatory activity of derivatives of 5 bromo vanilin was better than this of derivatives of 5 -nitroanilin.
Anti-Inflammatory Agents ; analogs & derivatives

In total, 511 Vietnamese patients (515 commit suicide events) admitted during the period from January 1, 1999 to April 30, 2001 were included in the study. The results shown that: nearly a half (48.7%) of the patients was in the age group of 15-24 years old. The female to male ratio of the patients living in the urban area (2.1:1) is higher than that in the rural area (1.2:1) with p<0.01. Among the patients: farmers (19.8%), students (24.7%) and homework (20.8%). Commit suicides were made more frequently in April with a significant difference between the urban and rural area (p=0.02). Conflicts with partners and other family members were the main causes of commit suicide. Anticarcotic and antipyretic were often used among the patients living in the urban, while pesticide and raticide more commonly in the rural areas as a means of commit suicide.
Suicide ; Poison Control Centers

Study two cases of primary amyloidosis with the pathognomonic symptom of macroglossia , the diagnosis and treatment of primary amyloidosis. The first one presented with lesions of the tongue, peripheral neuropathy and the bone marrow aspiration revealed <30% plasmocyte with neither bone destruction nor heart, kidney injury. The second case showed diffuse infiltration of amyloid, not only caused the macroglossia but also led to the injury of the heart, pleura, kidneys, subcutaneous tissues, and the autonomic nervous system with postural hypotension
Amyloidosis ; Macroglossia ; Hypotension, Orthostatic ; diagnosis ; Therapeutics

A restrospective study carried out on 309 patients with chronic myelogenous leukemia treated from 1990 to 10/2000 showed that; -88 cases (28.3%) converted to the blast crisis. - 89.77% of these cases developed acute myeloblastic leukemia (AML) and 9.09% developed ALL.-The percentage of male and female were 55.68% and 44.31% - 45.45% of these converted cases occurred in the age group of 30-50. The youngest age was 10 months and the oldest age was : 72 years old. Mean of duration of the chronic phase was 2.5 years.
Leukemia, Myeloid, Chronic ; Leukemia, Myeloid, Chronic-Phase

On experimental rats, the effect of pain relieve, of neuroleptic and acute toxicity of Formula D1 was studies. The formula composes of 9 componants (Bach truat, Hoang ky, Chi thuc, Moc huong, Nghe, Cam thao, Lac tien, Bach thuoc, Huong phu). It manifests an effects of analgesic on white mouse, experimented with the method of heat plate and Koster. The formula inhibits Central nervous system, it has not acute toxicity when administered orally in dose of 73 folds of therapeutic dose
Chemistry, Pharmaceutical ; Medicine, Traditional ; Therapeutics ; drugs

An one year old girl with congenital torticolis was subjected to study. At birth, an oval neck mass was persisted at the right side, which made the head tilted. The patient was treated by massage to reduce the contraction of clavicle muscle. Infra-red was irradiated during 10 minutes in the neck and the left side lumbar regions. Exercises were practised to rotate the neck and the trunk, and to stretch the neck. Mother was trained for holding and carrying the child at home. 4 months of treatment gave good results
Torticollis ; Therapeutics ; Physical Therapy (Specialty)