Cot khi cu was studied on experiment animals. Pain relief effect was evaluated with 1% extract, sedative and hypnotic effect was compared with hexobarbital and acute toxicity was assessed by Lichfield Wilcozon Method. Results showed that raw and processed Cot khi cu did not cause acute toxicity, with a dose of 200 folds of clinical dose. In raw and processed Cot khi cu, there is no defference in pain relief effect. Roast Cot khi cu gave a better sedative effect than the raw Cot khi cu
Acute Toxicity Tests ; Animals ; Biochemistry ; drugs

The anti-flammatory effect of Drynaria fortunei was studied on rat’s hind paw edema induced by carrageenin. Results showed that its aqueous extract in the dose of 4g/kg body weight exerts anti-inflammatory effect. Acute effect of Drynaria fortunei is exhibited through the decreased quantity of exudation and the number of leucocyte in the exudation.
Anti-Inflammatory Agents ; Animal Experimentation ; Medicine, Traditional

2.280 people living in DongDa district, Hanoi city were randomly selected and interviewed concerning the health status, the physical illness the emotional troubles as well as the habit of use of alcohol, sleeping medication, pain medication, and their suicidal thought in whole life. The results showed that there is an association between the suicidal thoughts and cancer, asthma. Anxiety, depression and fear were considered predictors for these thoughts, the habit for using sleeping and pain relief medications were associated statistic significantly with the suicidal thoughts but there was not an association with the use of alcohol.
Population ; Suicide ; Sick Role

The effect of analgetic and anti inflammatory of Tinospora Sinensis Men were studies in the form liquid glue on experimental mice. These mice were divided into 4 groups: group 1 takes NaCl 0,9%; group 2 takes Aspegic; group 3 takes liquid glue with dose 4g/kg; group 4 takes liquid glue with dose 8g/kg. The results were: after 5 min causing pain, aspegin and Tinospora Sinensis Men relieves pain clearly. After 15 min, these two drugs also has effect vigorous (58.88 – 88.5%) compared to control group with P<0.001. Dose 4g/kg of Tinospora Sinensis Men had not effected yet acute anti inflammatory clearly. Dose higher 8g/kg can inhibit inflammatory reaction on leg of mice with 10,16% (P<0.005), less than aspegic 0.05g/kg. The conclusion: Tinospora Sinensis Men has effect relieving pain by peripheral machanism, anti inflammatory acute and relievring oedematose reaction local with dose 8g/kg
drugs ; Medicine, Traditional ; Pain ; Anti-Inflammatory Agents

Study on acute and subchronic toxicity of CP preparation (extracted from Cu Binh Voi) finding using CP preparation with 1000mg/kg mouse of dose, follow in 72 hours, not any mice died. With 30mg/kg mouse uninterrupted take in 30 days, CP preparation didn’t effect to making blood function (but reduced number of leukocyte). It exchanged effect of eliminate urea thourgh renal. It not exchanged tranxaminaza level in serum but slightly effect to sterilize function of rabit
Medicine, Traditional ; Biochemistry ; Plant Extracts

Study on ‘Cot toai bo’ (Drynaria bonii Rhizome) product was processed from fresh stem and root of Drynaria bonii Christ., collected at Lang Son from July 2003 to September 2003. Results: chemical analysis showed that Cot toai bo contains flavonoids, steroid saponins, sterols, tannins, deoxidized sugar. Total flavonoid in stem and root accounted for 0.60±0.03% and total saponin was 3.71±0.06%. After processing by traditional method, total flavonoids and saponins in processed materials reduced in comparison with raw material. Compare 2 processing methods: in rice alcohol processed material, whose chemical constituents were reduced very little but in fried material, whose chemical constituents were reduced more than raw material. Rice alcohol processed Cot toai bo had analgesic and anti-inflammatory effects better than raw material and this processing was a more appropriate method than fried method
Polypodiaceae ; Rhizome ; Chemistry

The study was carried out with healthy white mice of the strain of Swiss, weighed 202 g, fed properly in good supply of water and food. Results a pain relief and narcotic effects of the material. An intensive dose 200 times higher than usual clinical dose did not manifest toxicity in the animal
Medicine, Traditional ; Chemistry, Pharmaceutical ; Acute Toxicity Tests

Cau tich fluid extract was studied on white mice. The dose of 4 g/kg of body weigh exerts against acute inflammation and relief the pain 2 hours, 4 hours, and 6 hours after the onset of inflammation. On the experimental granuloma, Cau tich has a moderate effect on chronical inflammation. In experimental model of “hot plate” Cau tich manifests a pain relief effect centrally and peripherally
Inflammation ; Medicine, Traditional ; Chemistry, Pharmaceutical ; drugs

Fluorescence in Situ Hybridization (FISH) is cytogenetics - molecular technique. FISH is the rapid detection technique of chromosomal aberration by chromosome specific probes applied to interphase cells. In this study, the authors used Kit duple DNA probe for chromosome 13, 21, X, Y to prenatal diagnosis of Down’s syndrome. With 6 amniotic fluid samples, the authors obtained the results as follows: 2 samples were Down’s syndrome trisomy; 1 sample was Patau syndrome trisomy; 3 samples were normal; 1 sample male foetus died without clear causes. Cytogenetic result: 46, XX but FISH result: 46, XY; PCR (Polymerase Chain Reaction) result: TDF (Testis Determining Factor): (+). These results were confirmed by chrosome analysis.
Down Syndrome ; Prenatal Diagnosis

In 1997 (1/1997-10/1997) with lymphocytes culture technique, technique for preparing chromosome slides, and Barr body technique (giemsa + trypsin). We determined Karyotyp for 60 patients with suspected genetic disorders. The result showed determined sex for 40 patients (Karyotyp 46,XX or 46,XY). 2 interrex with Karyotyp 46,XX/46,XY. 2 intersex with Karyotyp 46,XX. Determining Karyotyp for 8 patients with suspected Turner Syndrome. One of them: 45,X/46, X, r(X). Determining Karyotyp for 2 patients with suspected Down Syndrome. (1 case: 46,XX; another: 47,XX, +21). Determining Karyotyp for another patients: suspected: panconi; 47,XYY; Sterility..
Genetics ; Chromosome Aberrations