The study was carried out with healthy white mice of the strain of Swiss, weighed 202 g, fed properly in good supply of water and food. Results a pain relief and narcotic effects of the material. An intensive dose 200 times higher than usual clinical dose did not manifest toxicity in the animal
Medicine, Traditional ; Chemistry, Pharmaceutical ; Acute Toxicity Tests

Cau tich fluid extract was studied on white mice. The dose of 4 g/kg of body weigh exerts against acute inflammation and relief the pain 2 hours, 4 hours, and 6 hours after the onset of inflammation. On the experimental granuloma, Cau tich has a moderate effect on chronical inflammation. In experimental model of “hot plate” Cau tich manifests a pain relief effect centrally and peripherally
Inflammation ; Medicine, Traditional ; Chemistry, Pharmaceutical ; drugs

Fluorescence in Situ Hybridization (FISH) is cytogenetics - molecular technique. FISH is the rapid detection technique of chromosomal aberration by chromosome specific probes applied to interphase cells. In this study, the authors used Kit duple DNA probe for chromosome 13, 21, X, Y to prenatal diagnosis of Down’s syndrome. With 6 amniotic fluid samples, the authors obtained the results as follows: 2 samples were Down’s syndrome trisomy; 1 sample was Patau syndrome trisomy; 3 samples were normal; 1 sample male foetus died without clear causes. Cytogenetic result: 46, XX but FISH result: 46, XY; PCR (Polymerase Chain Reaction) result: TDF (Testis Determining Factor): (+). These results were confirmed by chrosome analysis.
Down Syndrome ; Prenatal Diagnosis

In 1997 (1/1997-10/1997) with lymphocytes culture technique, technique for preparing chromosome slides, and Barr body technique (giemsa + trypsin). We determined Karyotyp for 60 patients with suspected genetic disorders. The result showed determined sex for 40 patients (Karyotyp 46,XX or 46,XY). 2 interrex with Karyotyp 46,XX/46,XY. 2 intersex with Karyotyp 46,XX. Determining Karyotyp for 8 patients with suspected Turner Syndrome. One of them: 45,X/46, X, r(X). Determining Karyotyp for 2 patients with suspected Down Syndrome. (1 case: 46,XX; another: 47,XX, +21). Determining Karyotyp for another patients: suspected: panconi; 47,XYY; Sterility..
Genetics ; Chromosome Aberrations

The 128 patients (78 males, 50 females) managed in the Nephrology Department, Chî RÉy hosptial, were enrolled in this study to compare the classical clearance creatinine 24h with the clearance creatinine estimated by Cockcroft Gault formula. Almost 2/3 patients had glomerular diseases, in which the majority was manifested by the nephritic syndrome. The range of clearance creatinine 24h varied from 0.02 ml/min to 131 ml/min. A good correlation between clearance creatinine/1.73m2 in 24h and estimated clearance creatinine/1.73m2 from Cockroft Gault formula (r=0.89, R2=0.8, p<0.0005), a regression line was drawn. There had a strong correlation in the subgroup of female and subgroup with serum creatinine (3mg% (r=0.985). In conclusion, the Cockroft Gault formula estimated clearance creatinine can be replaced the classical clearance 24h on the evaluation of kidney function in renal disease patients
Kidney ; Kidney Function Tests

The authors report a histological study of chronic gastritis. Results are as follows: Chronic gastritis showed high rate of chronic atrophic gastritis (76.1%), among them mild atrophic gastritis is 60%, moderate and severe atrophic gastritis is 15% and 1.1%, respectively. The majority of gastritis is in active chronic gastritis patterns (75%); H. pylori infection rate is 52.1%. Intestinal metaplasia was detected in 31.8%. The rate of complete intestinal metaplasia is higher than that of incomplete intestinal metaplasia (63.3% vs. 36.3%). Dysplasia was revealed in 7.9% (low grade: 77.3%; high grade: 22.7%. There is a significant correlation between atrophic levels and the rate of metaplasia and dysplasia.
Gastritis ; Anatomy & histology

143 lecturers and 1360 students in basic, biomedical, clinical and community departments of Ha Noi Medical University were interviewed on the current situation of training methods. The results showed that 38.4% teachers applied active training methods and there is a dramatic change in comparison to prior 1995 in biomedical group (p<0.05), more than 70% lecturers had syllabus, gave questionnaires and assessment after lesson. 60% lecturers reported that traditional training methods made students become negative while active method made students more active. 54.2% of students read references that related to clinical subjects. 96.5% of students read the bulletin of basic medical departments. 61.2% students like the active methods in training
education ; Methods

From 1990-2000, 1.282 cases with IPT, who diagnosed and treated, consist of 499 (38.9%) children and 783 (61.6%) adults at Blood Transfusion and Hematology Centre HCM city. Almost the patient were treated with corticoid (2mg/kg/body weight/day) protocol. Minority another patient were treated by gamma globulin. Results of corticoid therapy regimens on children were complete response: 77.8% partial response: 9%, dependent of corticoid: 2.5% and, no response: 10.7%, while the effect of this therapy in adults was low. Rate of persistent ITP after 6 months (chronic ITP) in children: 23.5%, in adults: 60%.
Purpura, Thrombocytopenic, Idiopathic ; Blood Transfusion ; Therapeutics

Healthy rats with weight of 120-180 g were randomly divided into 4 groups. They tested the anti-acute inflamatory activity of T1 (3 -methoxy 4 hydroxy-5 bromobenzylidien para bromo anilin) and T2 (3-methoxy 4 hydroxy-5 nitrobenzylidien p-nitro anilin). The results have shown that T1 had a significant antiinflamatory activity after 2 h and 4 h of the test but had no antiflamatory activity after 6 h of the test comparing with the control. While the anti-inflamatory activity of T2 was not different from this in the control. This study concluded that the anti-inflamatory activity of derivatives of 5 bromo vanilin was better than this of derivatives of 5 -nitroanilin.
Anti-Inflammatory Agents ; analogs & derivatives

In total, 511 Vietnamese patients (515 commit suicide events) admitted during the period from January 1, 1999 to April 30, 2001 were included in the study. The results shown that: nearly a half (48.7%) of the patients was in the age group of 15-24 years old. The female to male ratio of the patients living in the urban area (2.1:1) is higher than that in the rural area (1.2:1) with p<0.01. Among the patients: farmers (19.8%), students (24.7%) and homework (20.8%). Commit suicides were made more frequently in April with a significant difference between the urban and rural area (p=0.02). Conflicts with partners and other family members were the main causes of commit suicide. Anticarcotic and antipyretic were often used among the patients living in the urban, while pesticide and raticide more commonly in the rural areas as a means of commit suicide.
Suicide ; Poison Control Centers