1.Acute toxicity and some pharmacological effects of "c?t khí c?", a traditional pharmaceutical material
Journal of Practical Medicine 2003;425(5):35-37
The study was carried out with healthy white mice of the strain of Swiss, weighed 202 g, fed properly in good supply of water and food. Results a pain relief and narcotic effects of the material. An intensive dose 200 times higher than usual clinical dose did not manifest toxicity in the animal
Medicine, Traditional
;
Chemistry, Pharmaceutical
;
Acute Toxicity Tests
2.The anti- inflammation and pain relief effects of " Cau tich" in experiment
Journal of Practical Medicine 2003;425(5):42-44
Cau tich fluid extract was studied on white mice. The dose of 4 g/kg of body weigh exerts against acute inflammation and relief the pain 2 hours, 4 hours, and 6 hours after the onset of inflammation. On the experimental granuloma, Cau tich has a moderate effect on chronical inflammation. In experimental model of “hot plate” Cau tich manifests a pain relief effect centrally and peripherally
Inflammation
;
Medicine, Traditional
;
Chemistry, Pharmaceutical
;
drugs
3.Using the Fluorescence in Situ Hybridization technique for prenatal diagnosis of Down’s syndrome
Journal of Practical Medicine 2005;530(11):9-11
Fluorescence in Situ Hybridization (FISH) is cytogenetics - molecular technique. FISH is the rapid detection technique of chromosomal aberration by chromosome specific probes applied to interphase cells. In this study, the authors used Kit duple DNA probe for chromosome 13, 21, X, Y to prenatal diagnosis of Down’s syndrome. With 6 amniotic fluid samples, the authors obtained the results as follows: 2 samples were Down’s syndrome trisomy; 1 sample was Patau syndrome trisomy; 3 samples were normal; 1 sample male foetus died without clear causes. Cytogenetic result: 46, XX but FISH result: 46, XY; PCR (Polymerase Chain Reaction) result: TDF (Testis Determining Factor): (+). These results were confirmed by chrosome analysis.
Down Syndrome
;
Prenatal Diagnosis
4.Using G banding technique to determine karyotyp for patients with suspected genetic disorders
Journal of Medical Research 1998;6(2):47-52
In 1997 (1/1997-10/1997) with lymphocytes culture technique, technique for preparing chromosome slides, and Barr body technique (giemsa + trypsin). We determined Karyotyp for 60 patients with suspected genetic disorders. The result showed determined sex for 40 patients (Karyotyp 46,XX or 46,XY). 2 interrex with Karyotyp 46,XX/46,XY. 2 intersex with Karyotyp 46,XX. Determining Karyotyp for 8 patients with suspected Turner Syndrome. One of them: 45,X/46, X, r(X). Determining Karyotyp for 2 patients with suspected Down Syndrome. (1 case: 46,XX; another: 47,XX, +21). Determining Karyotyp for another patients: suspected: panconi; 47,XYY; Sterility..
Genetics
;
Chromosome Aberrations
5.Whether estimated clearance createinine by cockeroft gault can substitute the clearance createnine 24 hours or not in patients with glomerular diseases
Journal of Vietnamese Medicine 2001;263(9):96-102
The 128 patients (78 males, 50 females) managed in the Nephrology Department, Chî RÉy hosptial, were enrolled in this study to compare the classical clearance creatinine 24h with the clearance creatinine estimated by Cockcroft Gault formula. Almost 2/3 patients had glomerular diseases, in which the majority was manifested by the nephritic syndrome. The range of clearance creatinine 24h varied from 0.02 ml/min to 131 ml/min. A good correlation between clearance creatinine/1.73m2 in 24h and estimated clearance creatinine/1.73m2 from Cockroft Gault formula (r=0.89, R2=0.8, p<0.0005), a regression line was drawn. There had a strong correlation in the subgroup of female and subgroup with serum creatinine (3mg% (r=0.985). In conclusion, the Cockroft Gault formula estimated clearance creatinine can be replaced the classical clearance 24h on the evaluation of kidney function in renal disease patients
Kidney
;
Kidney Function Tests
6.Histology of chronic gastritis
Journal of Vietnamese Medicine 2001;256(2):118-122
The authors report a histological study of chronic gastritis. Results are as follows: Chronic gastritis showed high rate of chronic atrophic gastritis (76.1%), among them mild atrophic gastritis is 60%, moderate and severe atrophic gastritis is 15% and 1.1%, respectively. The majority of gastritis is in active chronic gastritis patterns (75%); H. pylori infection rate is 52.1%. Intestinal metaplasia was detected in 31.8%. The rate of complete intestinal metaplasia is higher than that of incomplete intestinal metaplasia (63.3% vs. 36.3%). Dysplasia was revealed in 7.9% (low grade: 77.3%; high grade: 22.7%. There is a significant correlation between atrophic levels and the rate of metaplasia and dysplasia.
Gastritis
;
Anatomy & histology
7.Primary amyloidosis: Diagnosis and treatment
Journal Ho Chi Minh Medical 2003;7(2):91-100
Study two cases of primary amyloidosis with the pathognomonic symptom of macroglossia , the diagnosis and treatment of primary amyloidosis. The first one presented with lesions of the tongue, peripheral neuropathy and the bone marrow aspiration revealed <30% plasmocyte with neither bone destruction nor heart, kidney injury. The second case showed diffuse infiltration of amyloid, not only caused the macroglossia but also led to the injury of the heart, pleura, kidneys, subcutaneous tissues, and the autonomic nervous system with postural hypotension
Amyloidosis
;
Macroglossia
;
Hypotension, Orthostatic
;
diagnosis
;
Therapeutics
8.Sumary of the duration of the phase transfer of chronic myeloid leukemia
Journal of Vietnamese Medicine 2001;257(3):1-4
A restrospective study carried out on 309 patients with chronic myelogenous leukemia treated from 1990 to 10/2000 showed that; -88 cases (28.3%) converted to the blast crisis. - 89.77% of these cases developed acute myeloblastic leukemia (AML) and 9.09% developed ALL.-The percentage of male and female were 55.68% and 44.31% - 45.45% of these converted cases occurred in the age group of 30-50. The youngest age was 10 months and the oldest age was : 72 years old. Mean of duration of the chronic phase was 2.5 years.
Leukemia, Myeloid, Chronic
;
Leukemia, Myeloid, Chronic-Phase
9.Preliminary assessment of pharmacological effect of the Formula D1
Journal of Practical Medicine 2003;442(2):58-60
On experimental rats, the effect of pain relieve, of neuroleptic and acute toxicity of Formula D1 was studies. The formula composes of 9 componants (Bach truat, Hoang ky, Chi thuc, Moc huong, Nghe, Cam thao, Lac tien, Bach thuoc, Huong phu). It manifests an effects of analgesic on white mouse, experimented with the method of heat plate and Koster. The formula inhibits Central nervous system, it has not acute toxicity when administered orally in dose of 73 folds of therapeutic dose
Chemistry, Pharmaceutical
;
Medicine, Traditional
;
Therapeutics
;
drugs
10.Congenital torticolis treated by physiotherapy: report of a clinical case
Ho Chi Minh city Medical Association 2004;0(3):145-146
An one year old girl with congenital torticolis was subjected to study. At birth, an oval neck mass was persisted at the right side, which made the head tilted. The patient was treated by massage to reduce the contraction of clavicle muscle. Infra-red was irradiated during 10 minutes in the neck and the left side lumbar regions. Exercises were practised to rotate the neck and the trunk, and to stretch the neck. Mother was trained for holding and carrying the child at home. 4 months of treatment gave good results
Torticollis
;
Therapeutics
;
Physical Therapy (Specialty)