Objective To explore the predictive factors of life quality of adult patients with chronic tonsillitis after tonsillectomy .Methods 68 adult patients with chronic tonsillitis treated with tonsillectomy admitted to our hos-pital from January, 2013 to June, 2014 were divided into the observation group (SF-36 score<50 points, n=38) and the control group (SF-36 score>50 points, n=30) according to SF -36 scale scores 1 week after operation. Life quality ( SF-36) score of the 2 groups before and after treatment were statistically analyzed .The predictive fac-tors of life quality of adult patients with chronic tonsillitis after tonsillectomy were analyzed by single factor analysis and logistic factors analysis .Results Life quality scores of preoperative eight dimensions in the 2 groups including physiological functions, physiological roles, physical pain had no statistically significant difference (p>0.05).Life quality scores of the two groups at weeks 1, 2 and 4 after surgery were higher than those before surgery .Life quality scores of the observation group after treatment were lower than those of the control group in the same period ( p<0.05).The results of single factor analysis showed that relative factors of life quality of adult chronic tonsillitis after tonsillectomy were gender, age, Hamilton depression rating scale (HAMD) scores and Hamilton anxiety rating scale ( HAMA) scores, etc..The results of logistic multifactor analysis showed that age , HAMD scores and HAMA scores were independent predictors of life quality of adult chronic tonsillitis after tonsillectomy .Conclusion Independent predictive factors of life quality of adult chronic tonsillitis after tonsillectomy includw age , HAMD scores and HAMA scores.Therefore, diets and sports can improve disease resistance ability of aged patients .And psychological condi-tion regulation can also effectively improve patient's life quality .

Objective To evaluate the therapeutic effect of highly active anti-retroviral therapy (HAART) in treatment-na(i)ve Chinese patients with AIDS, to provide evidences for standardizing HAART.Methods Seventy-four treatment-naive AIDS patients were initiated with HAART and followed up regularly for 3 years. The clinical and laboratory data, side effects and drug resistance were observed and analyzed during the follow-up period. Results Of the 74 patients, 46 were males and 28 were females, with the average age being 42 years. The mean HIV viral load was ( 2. 2 ± 2.0 ) × 105 copies/ml and the baseline mean CD4+ T lymphocyte count was (62 ± 71 )cells/μl before treatment. After treatment for 3, 6, 12, 18,24, 30 and 36 months, the percentage of undetectable HIV viral road (less than 50 copies/ml ) was 71.6%, 83.8%, 75.7%, 77.0%, 82.4%, 81.1% and 79.7% respectively, and CD4+T lymphocyte count ascended to ( 167 ± 105), ( 177 ± 129), (238 ± 137), (290 ± 158), (304 ± 191 ), (331 ± 175) and ( 352 ± 202 ) cells/μl. The increase in amplitude of CD4+ T lymphocyte count in different periods examined was different, with the period of 0-3 months post-treatment demonstrating the most obvious augmentation ( P ＜ 0. 01 ) . The most common adverse reactions were liver function injury ( 52/74,70. 3% ), hyperlipemia (52/74, 70. 3%), hematopoietic inhibition of the bone marrow (33/74, 44. 6% ),peripheral neuritis (32/74, 43.2% ) and lipoatrophy (26/74, 35. 1%). Clinical drug resistance were found in nine patients and HIV gene mutations were detected in these patients. Conclusions Chinese treatment-naive AIDS patients have achieved good virological and immunological response to generic-drugpredominant HAART regimes with low drug resistance, but relatively more side effects.