Introduction: The basis of the development of traditional Mongolian medicine in the 21st century is the importance of reading and studying the biographies of previous generations of ancient doctors and scientists, as well as old medical books and sutras. For example, it is important to gain a deeper understanding of the scientific basis of the ancient medical books, and to understand the manuals and treatment’s methods of doctors and maarambas. Research goal: Studying the biography of Erdene Bandida Khutagt, Khamba Nomuun Khan Hanchen Choijal Luvsandanzanjantsan, and his medical book titled “gsal ba’i sgron me”. Research methods: We used following study methods; manuscripts, primary source methods, hermeneutic method, matrifocal listing method, historical comparative method and analysis synthesis method. Result: Erdene Bandida Khutagt, Khamba Nomuun Khan Hanchen Choijal Luvsandanzanjantsan, the first incarnation of the Lama Gegeen, was born on the 15th of January 1639, in Ulziit Ovoo, Sain Noyon Khan aimag. In 1643, at the age of five, he was initiated by Namkhaisodnomdagva and named Choijidorj. In 1644, at the age of six, he went to Tibet in order to study Tibetan script, calligraphy, and secret tantric rituals and other subjects including medicine taught by Luvsanyarpel, who came to Mongolia from the Dashlkhumbe Monastery of Tibet. Thus, from an early age, he was immersed in religious and medical teachings. Luvsandanzanjantsan has written five books in Tibetan. We selected the book titled “mkhan chen chos kyi rgyal poi gsung ‘bum las gso ba rig pa’i rtsa rgyud kyi’ grel pa gsal ba’i sgron me ces bya ba bzhugs so” as our main subject of study. The book clearly explains the “Root Tantra” of the “Four Medical Tantras”, clarifies the difficult words and content of the theory and makes it easier for people to learn. In addition, we have studied the structure, content, and concluding remarks of this book. Conclusion Luvsandanzanjantsan was not only a scientist who penetrated the five great sciences, but also made a valuable contribution to the expansion of Mongolian medical research field and the introduction of Tibetan medicine into Mongolia. He is credited with reviewing and commenting on the best medical works of Indian and Tibetan scholars.