1.Comparison of effects of two kinds of anesthetics in treatment of pregnant women with acute pericoronitis of wisdom tooth
Chongqing Medicine 2017;46(10):1363-1364
Objective To observe the anesthetic effect onset of primacaine and lidocaine in the treatment of pregnant women with acute pericoronitis of wisdom tooth.Methods.Two hundreds pregnant patients with acute pericoronitis of wisdom tooth were randomly divided into the study group and control group,100 cases in each group.The study group adopted primacaine before treatment,while the control group adopted lidocaine.The anesthetic effects were compared between the two groups.Resuits The anesthetic effect onset in the study group was faster than that in the control group,the difference was statistically significant (P<0.01).The two groups all reached a better analgesic effect,moreover the pain degree and fear degree had no statistical difference between the two groups (P>0.05).Conclusion The anesthetic effect of primacaine and lidocaine in the treatment of pregnant women with acute pericoronitis of wisdom tooth is favorable with high patient's satisfaction.
2.Status epilepticus cases clinical feature and treatment in 86 patients
Chinese Traditional Patent Medicine 1992;0(02):-
AIM: To investigate 86 patients (age range, 12 to 80 years; mean?SD age 48.63?18.11) who had status epilepticus. Among them 60 patients had generalized tonic-clonic status epilepticus, 21 myoclonic clo-nictonic clonic status epilepticus 3 generatized tonic status epilepti-cus and 2 patients complex partial status epilepti-cus-psychomotor status epilepticus. METHODS: We conducted two centers, of 45 patients were given Sod. Phenobarbital im group and of 41 patients were given Diazepam Ver iv group. RESULTS: Significant difference in control with status epilepticus, (28.53?10.95) min and (33.85?11.53) min, P
3.PRODUCTION AND APPLICATION OF DIALYSIS SHEETS
Modern Hospital 2015;(10):66-67,70
Objective To produce a new type of medical bed sheet suitable for hemodialysis .Methods Application effect of traditional methods compared hemostatic clamp fixed cycle trail tube with the use of dialysis sheets fixed cycle trail tube method in hemodialysis .Results Dialysis sheets of reasonable structure setting has the advantages of convenience and practicality than using sterilized forceps traditional fixed mode .The adaptability is strong, and preparation cost is low .The fixing device and the sheets are fixed as a whole , without also prepare disin-fection clamp fixed cycle trail tube , not circulating blood road pipe clamp bad , and put an end to the sheets caused by repeated clamping forceps to damage , and can be used as a piece of goods one -time cleaning and disinfection .Con-clusion The standard of energy saving and consumption reduction is achieved by dialysis bed sheets , which can a-chieve the goal of controlling and improving the quality of medical care .
4.Analysis of oral Health care knowledge in 478 outpatients
Journal of Chongqing Medical University 2007;0(07):-
Objective:To investigate the prehension status of outpatients for oral health care knowledge.Methods:Refering to scheme of oral health propaganda in West-Pacific area instituted by World Health Organization,self-designed questionnaire was used and 478 outpatients with diferent education levels were interviewed about the prehension for oral health care knowledge. The results were analyzed.Result:There was no difference among patients with different sexes in basic oral health care knowl- edge,but with regard to the question that there is association between cigarette and periodontal diseases,the prehension status of female patients was better than that of the male patients.Meanwhile,The prehension status of the patients with university e- ducation was better than that of the patients without university education,but generally,the correct rate was not high.Conclu- sion:The education level will affect the prehension status.The prehension status of outpatients for oral health care knowledge is not ideal.We must emphasize the importance of the oral health care and the oral health care knowledge education.
5.THE CLINICAL SIGNIFICANCE OF IgA ANTI-HBc IN VIRAL HEPATITIS B
Medical Journal of Chinese People's Liberation Army 1983;0(05):-
We have developed an antibody-captured sandwich-type enzyme linked immunosorbant assay(ELISA) with monoclonal anti-IgA/a (human) and monoclonal anti-HBc, and determined immunogloblin A against hepatitis B core antigendgA anti-HBc) in sera of 179 cases of various types of HBV infection. IgAanti-HBc in the patients with acute hepatitis B (14 cases) and severe hepatitis (7 cases) was all positive, while in the patients with chronic active hepatitis, cirrhosis, chronic persistent hepatitis, and symptomatic carriers the positive rates were 94% (47/50 cases), 83.3% (10/12 cases), 56.5%(26/46 cases) and 4%(2/50 cases), respectively. Our observations suggested that IgA anti-HBc may reflect hepatic damage in the patients with HBV infection. Its detection may be valuable in the diagnosis and prognosis HBV infection. In addition, the activity of IgA anti-HBc in chronic hepatitis B is related to HBeAg.
6.Effects of ziprasidone on serum cholinesterase concentration in schizophrenia patients
Journal of Pharmaceutical Practice 2020;38(1):88-90
Objective To explore the effects of ziprasidone and clozapine on serum cholinesterase (CHE) concentration in schizophrenia patients. Methods 126 schizophrenia patients were randomly divided into the observation group and the control group. The observation group was treated with ziprasidone. The control group received clozapine. The serum CHE concentration was assayed at 7, 14 and 28 days after treatment. Results ① The PANSS scores in both groups were significantly reduced after treatment, while the control group was lower than the observation group (PANSS score for positive symptoms: 15.3±4.7 vs 22.4±4.8, P<0.01; negative symptoms: 14.6±4.5 vs 21.8±5.2, P<0.01; general psychiatric symptoms: 13.3±3.4 vs 19.2±3.9, P<0.01). ② CHE levels were decreased in both groups after treatment. The control group exhibited greater decrease than the observation group. ③ The observation group had lower adverse reaction rate (34.9%) compared to control group (71.4%). Conclusion ziprasidone has weaker inhibitory effect on CHE activity compared to clozapine. This may explain that ziprasidone has lower therapeutic efficacy and better safety profile.
7.Comparison of three kinds of operation mode for treatment of ovarian cyst
Chinese Journal of Primary Medicine and Pharmacy 2015;(8):1207-1209
Objective To compare the effectiveness of the three operation mode in treatment of ovarian cyst. Methods According to the digital table,138 patients with ovarian cyst were divided into three groups,the group A (n=46 cases)were operated through open operation,group B (n =46 cases)were operated through transvaginal operation,group C(n=46 cases)were operated through laparoscopic operation.The three groups were observed the situation of operation (operation time,bleeding volume,the first exhaust time,hospitalizationtime ),complications (infection,hemorrhage,perimenopausal changes ),postoperative follow -up for 1 years.The recurrence rate was observed.Results Group A of 46 patients were successfully completed surgery,B,C groups of 1 patients was con-versed to laparotomy due to severe adhesion.B,C groups in the operation time,amount of bleeding during the opera-tion,the time of hospitalization were significantly less than that of group A (t=4.306,5.172,3.012,3.926,3.776, 2.168,P<0.05,P<0.01).B group was significantly less than those of A,C group in the first exhaust time (t=3.014,2.446,all P<0.05).In the operation time of group B was obviously less than that of group C (t=2.748,P<0.05).A,B,C three groups of postoperative complication rates were 39.1%,11.1%,15.6% respectively;the incidence of complications of B,C groups was lower than that in A group (χ2 =9.82,8.64,all P<0.01 ).After 1years follow-up,the recurrence rate in group B was significantly higher than that of A and C groups (χ2 =6.72, 6.72,all P<0.01).Conclusion Treatment of ovarian cyst vaginal surgery and laparoscopic surgery wound is small, but the person that weigh should be performed open adhesion treatment,individualized treatment.
8.Effect of Acupuncture at Points Taiyang and Fengchi on Heat Shock Protein 70 and Apoptosis during Cerebral Ischemia and Reperfusion in Rabbits
Shanghai Journal of Acupuncture and Moxibustion 2015;(11):1122-1125
Objective To investigate the effect of acupuncture at points Taiyang and Fengchi on the expression of heat shock protein 70 (HSP70) and neural cell apoptosis during local cerebral ischemia and reperfusion in rabbits and explore its protective action on nerve cells and the mechanism.Methods Rabbits were randomized into sham operation, model and acupuncture groups. Each group was randomly allocated to three time points: one, three and seven days. A rabbit model of local cerebral ischemia and reperfusion was made by middle cerebral artery occlusion (MCAO)using an intraluminal thread. Reperfusion was performed at two hours after cerebral ischemia. In the acupuncture groups, points Taiyang and Fengchi were electro-acupunctured at six hours after cerebral ischemia. Treatment was given once daily. The rabbits were sacrificed to take materials at one, three and seven days after reperfusion. Pathological changes in brain tissue were observed by HE staining. Cerebral HSP70 expression was determined by immunohistochemical method. Neural cell apoptosis was examined by TdT-mediated dUTP nick end labeling (TUNEL).Results Pathological staining showed that cerebral infarction area decreased significantly, the number of nerve cells increased and inflammatory infiltration reduced at every time point in the acupuncture group of rabbits compared with the model group. The results of histochemical examination showed that HSP70 expression decreased in the sham operation group and increased in the model group. It increased significantly at every corresponding time point in the acupuncture group compared with the model group (P<0.01). The number of apoptotic cells increased gradually with reperfusion prolongation and reached the peak at three hours in the model group. The number of apoptotic cells decreased significantly at every time point in the acupuncture group and there was a statistically significant difference by comparison with the model group (P<0.01).Conclusions Electroacupuncture at points Taiyang and Fengchi can increase cerebral HSP70 expression and decrease neural cell apoptosis to produce a nerve-protecting effect in rabbits with cerebral ischemia-reperfusion injury.
9.Ethical reflections on Fu biao's twice liver-transplantations:the distributive justice of scarce health-care resouces
Chinese Medical Ethics 1995;0(03):-
Fu biao who got an advanced liver cancer had undergone liver-transplantation twice and died at last,which raises great ethical concern.With respect to distribution,there are four substantial distributive principles,including the principle of equality,the principle of need,the principle of contribution,the principle of effort.When allocating scarce health-care resouses,medical criteirion should be considered firstly the equality of everyone's life.Furthermore,the principle of utility and equality should be embodied for ensuring distributive justice.
10.The design and implementation of real-time transmission system for pre-hospital emergency ECG
China Medical Equipment 2017;14(9):116-119
Objective:To design real-time transmission system for pre-hospital emergency electrocardiogram(ECG) so as to provide specialty and accurate diagnostic analysis about ECG before patient achieved at hospital and to shorten the waiting time for diagnosis and treatment after they achieved at hospital.Methods: 4G network and virtual private dial-up network(VPDN) were used to real-time transmit ECG data of patient from ambulance to hospital so as to doctors of ECG department and emergency room can analyze the detecting reporter, choose plan of emergency guidance and prepare operation and treatment for patientsaccording to the received ECG data in time.Results: The situations of emergency patients have been grasped and been primarily confirmed before they achieved hospital, therefore, the doctors could made relative preparation for fast and specially treating patients after they once achieved hospital.Conclusion: The real-time transmission system of pre-hospital emergency ECG can remedy the shortage of technical strength of pre-hospital emergency team, and shorten the treating time of emergency patients, and increase the success rate of rescue.