1.Study and Application of Outpatient Infusion Procedure
Huiying QIAN ; Juemin WANG ; Jianqiang ZHU
Chinese Medical Equipment Journal 1989;0(03):-
Objective To design a new procedure for outpatient safe infusion.Methods Aiming at the errors possibly occur in current management of hospital outpatient infusion process,modern wireless and intelligent recognition technology are applied to research and design a new infusion procedure.Results Based on its program difference from the LAN technology of fixed-point check transfusion management style,this solution truly met the needs of actual medical infusion process and achieve the dynamic information check,exchange and matching between the hospital staffs and patients.Conclusion It ensures the safety of transfusion patients,and creates a harmonious environment for treatment.
2.Air Disinfection Effect by Using Nanophotocatalytic Air Disinfector in Emergency Room
Yan WANG ; Huiying ZHU ; Yanchun LI
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To observe the sterilization effect of nanophotocatalytic air disinfector(NPD) on the indoor air of emergency room.METHODS Under the static and active circumstances,the on the-spot sterilization was adopted and observed.RESULTS In the static circumstances,after the machine had properly functioned over 60 minutes,the elimination rate of natural bacteria in debridement room and dressing change area reached 100.00% and 90.44%,respectively;in the active,after the machine had properly functioned over 60 minutes,the elimination rate of natural bacteria in debridement room and dressing change area reached 95.99% and 86.68%,respectively.The bacteria amount in the air decreased as the sterilization time was extended.CONCLUSIONS The NPD has good sterilization effect on indoor air.It can be adopted for the air sterilization in the emergency room under active circumstances.
3.Promotion effect of recombinant human granulocyte-macrophage colony stimulating factor on wound healing of gingiva in rabbits
Huiying ZHU ; Yanhai CHE ; Pan HE ; Ning MA
Journal of Jilin University(Medicine Edition) 2014;(6):1206-1209
Objective To investigate the effects of recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF)on the gingival wound healing, and to lay a foundation for its application in the field of oral cavity.Methods 16 healthy rabbits were randomly divided into experiment and control groups(n=8).2 mm upper and lower incisors’labial gingivae were removed by scalpel. After operation, rhGM-CSF gel was applied to the surface of the wound gum in experiment group,while saline instead of drugs to the control group.2 rabbits were executed at 3,7,11,and 15 d after operation.HE staining was performed to observe the epithelium and epithelial connective tissue structure, distribution, and the changes of various cells of the rats;the number of positive epithelial cells and fibroblasts were observed by PCNA dyeing.Results On the 3rd day,the inflammatory cell infiltration was found in two groups, but a greater number of the cells were observed in experiment group;neovascularization was seen in both groups on the 7th day,and the fibroblasts and collagen fibers were observed too,but the extent of neovascularization in experiment group was more significant. On the 11th day, the fibroblasts proliferation was seen in two groups,but the extent in experiment group was more widely;on the 15th day,the trauma of gingivae of the rabbits in two groups returned to normal,there was no significant difference between two groups.Over time,the number of epithelial cells in proliferation was gradually increased,reached the peak on the 15th day.The number of fibroblasts began to increase from the 3rd day and reached the peak on the 11th day,and significantly reduced to the lowest value on the 15th day.The number of proliferative epithelial cells in experiment group was significantly higher (P<0.01)on the 3rd day and the 11th day than those in control group (P<0.01);the number of proliferative fibroblasts was significantly higher (P<0.05)on the 11th day and the 15th day than those in control group (P<0.05 ), but there were no significantly statistical differences between two groups at other time pionts(P>0.05).Conclusion RhGM-CSF can promote the infiltration of inflammatory cells, angiogenesis,proliferation of epithelial cells and fibroblasts in gingivae. RhGM-CSF is beneficial with wound healing on gum tissue.
4.Investigation of the Current Situation of Pharmacy Department in Hospitals of Bengbu
Wenjun ZHU ; Zhiming XIN ; Genshen YE ; Lei WANG ; Huiying CHEN
China Pharmacy 2016;27(24):3328-3330
OBJECTIVE:To provide reference for improving the rationality of the personnel of pharmacy department and pro-moting the development of related pharmacy work in hospitals of Bengbu. METHODS:Questionnaire was designed to investigate and statistically analyze the general situation of secondary and tertiary hospitals in Bengbu in aspects of personnel,dispensing work-load and post setting,suggestions were put forward. RESULTS:Totally 13 questionnaires were sent out,10 were effectively re-ceived with the effective rate of 76.9%. The average proportion of investigated pharmacy staff to the whole health technical workers was 5.0%;primary pharmacist was 39.0%,chief pharmacist was 2.2%;college education was 44.9%,master degree or above was 3.0% ;the average daily prescription volume of outpatient was 375,daily trips of inpatient department was 267;4.4% of the staff were engaged in clinical pharmacy,only 4 hospitals carried out clinical pharmacy work;only 1 hospital had the Pharmacy Intrave-nous Admixture Service (PIVAS). CONCLUSIONS:The hospital pharmacy personnel configuration is not reasonable in Bengbu, dispensing is overloaded,the development of PIVAS is lagging behind,clinical pharmacy work remains to be further improved. It is suggested to promote the work of hospital pharmacy by increasing the numbers of pharmacy personnel,technical titles and practi-cal skills of the pharmacy staff,strengthening the construction of PIVAS and the cultivation of clinical pharmacists according to the condition.
5.Methods and Experiences of Standardized Management for Rinse and Disinfection of Endoscope
Huiying ZHU ; Hongtao CAO ; Xiaohong RUAN ; Yan WANG
Chinese Journal of Nosocomiology 2006;0(03):-
OBJECTIVE To assure the medical safety,enhance the medical care,prevent medical infection by(endoscope) examination and do effectively the standardized management for rinse and disinfection of endoscope.METHODS Strengthening the organization,to establish and consummate the system,increase the devotion of(facilities,) organize personal training and standardize the work procedures.RESULTS The work for rinse and(disinfection) of endoscope in hospital came to be standardized management gradually.CONCLUSIONS The(standardized) management for rinse and disinfection of endoscope is the assurance for the validity and security of(endoscope) sterilization.
6.Management and Occupational Protection Against HIV/AIDS in Hospital
Huiying ZHU ; Xiaoyan WANG ; Hongtao CAO ; Yan WANG
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To enhance the management against the HIV and AIDS,strengthen the awareness of occupational protection among medical staff,and prevent the HIV spreads in the hospital.METHODS To establish the HIV/AIDS monitoring report management system,launching AIDS knowledge training,screening HIV seriously in hospital,sterilizing strictly with the medical instrument and managing the medical discards,and standardizing procedures of the medical nursing and process after the occupational exposing.RESULTS Through establishing the HIV/AIDS monitoring report management system and launching occupation protection training,the awareness of medical staff for precaution against the HIV/ AIDS was enhanced obviously.They could discover the patients early and take the effective measures for protection,sterilization and isolation in time.The average number of diagnosis days for HIV/AIDS patients shortened obviously than before.CONCLUSIONS Through enhancing management and supervision for HIV/AIDS in hospital,paying more attention to safety education for medical staff,we can prevent the AIDS spreading in the hospital and reduce the occurrence of occupational exposure among medical staff.
7.Analysis and Preventive Strategy of Occupational Exposure to Blood Source Among Medical Staffs
Huiying ZHU ; Yan WANG ; Adan SHEN ; Yanchun LI ; Peng HAN
Chinese Journal of Nosocomiology 2009;0(21):-
OBJECTIVE To monitor the risk of occupational exposure among medical staffs and give the preventive measures.METHODS The profession high risk factor,element of sharp instrument injury,the risk of evaluation after exposure and preventive medication in 95 blood-borne among medical staffs from Nov.2005 to 2008 were analyzed.RESULTS Among the occupational exposure degree to blood source among medical staffs,the first was nurses(75.79%),the second doctors(16.84%).The sharp instrument injury was the most common type of the occupational exposure to blood source,and common appeared in the pinhead of infusion apparatus,and most appeared at the withdrawal of needles after transfusion completed or bare-handed.No staff got the infection brcause of occupational exposure to three HIV patients.CONCLUSIONS It is the key to cut down the risk of occupational exposure by enhancing the training of medical staffs,specification of procedure,enforcing standard precautions,establishment monitoring system,strengthening the report and effective treatment after exposure.
8.Expression of CD25and CD69on T Cells of Patients With Psoriasis Vulgaris
Kejian ZHU ; Huiying SHANG ; Limin LAO ; Min ZHENG
Chinese Journal of Dermatology 1995;0(03):-
0.05).Expression of CD25and CD69on CD8 + T cells was significantly higher in patients(16.30%?5.97%and32.61%?6.36%)than that in control group(9.21%?2.14%and10.03%?2.35%)(P
9.Research progress of immunohistochemical markers related with pancreatic cancer prognosis
Peng ZHU ; Huiying LIU ; Zhiqian HU ; Weijun WANG
Journal of International Oncology 2014;41(10):767-770
Pancreatic cancer is a malignant with very poor prognosis.Although methods and technologies of diagnosis and treatment in connection with pancreatic cancer have made great progresses,the prognoses of patients with pancreatic cancer still have not a significant upgrade,which are closely related with the degree of malignancy of pancreatic cancer cells.Earlier studies have shown that normal pancreatic cells need to have a total of six capabilities,which are intimate connection with the degree of malignancy of pancreatic cancer cells,during the process of deterioration.A variety of immunohistochemical markers that correlate with prognosis of pancreatic cancer involve in the process of pancreatic cells obtaining these six capabilities.
10.Botulinum toxin in the treatment of sialorrhea attributable to brain damage : A preliminary study
Guoqing YOU ; Huiying LIANG ; Lin LIAO ; Huihuan ZHU ; Yingzhang CAI
Chinese Journal of Physical Medicine and Rehabilitation 2014;36(12):936-938
Objective To evaluate the effect of ultrasound-guided botulinum toxin A injection into the salivary glands in treating patients with sialorrhea attributable to brain damage.Methods Nine subjects with sialorrhea attributable to traumatic brain injury (n =5),cerebral infarction (n =3) and hypoxic ischemic encephalopathy (n =1) were recruited into the study.With the guidance of ultrasound,15 units (U) of botulinum toxin type A was injected into the highest and lowest points of the two parotid glands,and 20 U was injected into two points of both submandibular glands.The saliva flow rate and the severity and frequency of sialorrhea were recorded before the treatment and 1 week,4 weeks and 12 weeks later using the Drooling Scoring System (DSS).Results The saliva flow rate before treatment (0.49 ± 0.12 g/min) decreased significantly to 0.24 ± 0.08 g/min after 1 week,but then increased again to 0.28 ±0.12 g/min after 4 weeks and 0.34 ±0.11 g/min after 12 weeks.The average DSS severity score showed the same pattern:4.35 ± 0.48 initially 1.92 ± 0.37 after 1 week,1.92 ± 0.37 after 2 weeks and 2.32 ± 0.64 after 12 weeks.The DSS frequency score,however,remained significantly lower:3.56 ± 0.49 initially,2.01 ± 0.42 after 1 and 4 weeks and 2.28 ± 0.63 after 12 weeks.Conclusion Botulinum toxin type A can effectively improve the salivary secretion and sialorrhea attributable to brain damage.