Objective To investigate the relationship between levels of psychological resilience and coping styles of the patients with recurrence of nasopharyngeal neoplasms during hospitalization,in order to provide scientific data about the clinical psychological intervention.Methods A total of 240 cases of hospitalized patients with recurrence of nasopharyngeal neoplasms were selected and measured with general information questionnaire which was self-designed,resilience scale (CD-RISC) and coping scale.Results Resilience average score of patients with recurrent nasopharyngeal neoplasms was (53.22 ± 12.09) points,the level of resilience was positively correlated with positive coping and avoidance coping,P＜0.05,and negatively correlated with the yield coping,P＜0.05.Conclusions The resilience levels in patients with recurrence of nasopharyngeal neoplasms is below the medium level,resilience have a significant impact on patients' coping styles,and coping styles is affecting the level of resilience.In clinical work,health care workers should take effective measures to improve the resilience of patients so that patients take positive coping with disease.

Objective To describe uncertainty in illness of patients with hepatocellular carcinoma intending to undergo transcatheter artery chemoembolization (TACE) and to identify the related factors. Methods A descriptive and correlative design was used. By convenience sampling, 95 patients with hepatocellular carcinoma were recruited from Sun Yat-Sen University Cancer Center in this study. Mishel Uncertainty in Illness Scale was used to assess uncertainty in illness and information needs of patients with hepatocellular carcinoma intending to undergo TACE and the demographic questionnaire and Information Needs Assessment Scale were used to measure demographic data, disease and treatment characteristics and information needs of patients. Results The level of uncertainty in illness in most patients with hepatocellular carcinoma intending to undergo TACE was middle (77.61±9.15) points. The mean score of indeterminacy subscale was (50.16 ± 6.16) points. Uncertainty in illness of patients with hepatocellular carcinoma intending to undergo TACE was affected by the degree of education background, domicile, family economic status, way to pay for the medical expenses, course of diseases, how many times he (she) used to undergo assisted treatments and the level of information needs. Conclusions The level of uncertainty in illness in most patients with hepatocellular carcinoma intending to undergo TACE was middle and it is important to assess patients′uncertainty in illness at clinical work and to take effective interventions to content patients′information needs to decrease the level of uncertainty.

Adherence refers to the extent to which a patient′s behavior coincides with medical advice without missing a dose or overdosing and taking drugs at the right time. Good adherence could assure the effect of the therapy and reduce neoplasm metastasis and recurrence as well. In this article, status of oral chemotherapy adherence in cancer patients, impact factors and measurement tools had been reviewed. Adherence of oral chemotherapy in cancer patients and measurement tools of oral chemotherapy adherence needed further study. Besides, nursing should also focus on impact factors of the adherence of cancer patients during the oral chemotherapy, and take effective interventions to improve the adherence, so as to ensure the effect of chemotherapy, and improve the survival rate of cancer patients.

Objective The study was to investigate the effect of psychological intervention on emotion and long-term effect of patients with nasopharyngeal cancer treated with radiotherapy. Methods A total of 100 patients with nasopharyngeal cancer were divided into the psychological intervention group and the control group with 50 cases in each. The patients in the psychological intervention group were given psychological intervention besides receiving radiotherapy and routine nursing which were similar to the control group. Anxiety score and depression score as well as survival rates before and after radiotherapy between two groups were compared. Results There was no difference in anxiety score and depression score between two groups before radiotherapy, but after radiotherapy, the anxiety score and depression score were more remarkably reduced in the psychological intervention group than in the control group. The 1, 3, 5-year overall survival rates were 100.0%, 94.0%, 85.9% respectively in the psychological intervention group, and were 96.0%, 85.6%, 70.7% respectively in the control group. Duration from the end of radiotherapy to relapse were (32.22±16.82) months in th psychological intervention group and (20.73±13.06) months in the control group. Conclusions Psychological intervention can improve anxiety and depression and shows a tendency to defer the occurrence of relapse and to improve the survival rate in patients with nasopharyngeal cancer treated with radiotherapy. The further research need to be done.

Objective In order to construct the standards of review for oncology nursing professional training base by aggregating the requirement of the professional training base in multiple regions in China.Methods Delphi expert consultation method by self-designed questionnaire were conducted among 21 nursing educators in medical university,nursing administrators,oncology clinicians,oncology clinical nurse specialists in hospitals.Results The Cr,Cronbach's α was 0.825,0.980.A standards of review for oncology nursing professional training base included 5 first-level indicators,19 second-level indicators and 76 third-level indicators after three rounds of consultation.Conclusions The 100-item for standards of the review is reliable and valid,which can provide objective and quantitative standards for evaluation,assessment and access of oncology nursing professional training base.

Background and purpose:Arsenic trioxide(As_(2)O_(3)) injection actually has an effect on solid tumors such as hepatoma in the clinic.In order to find out its mechanism of action,we studied the action of arsenic trioxide injection on angiogenesis of chick embryo chrioallantoic membrane(CAM).Methods:The effect of arsenic trioxide injection on angiogenesis was investigated by CAM model and computer image analysis.Results:Administered at three different concentrations of arsenic trioxide injection at 10,20 and 40,3 days later,the vessel area were 25.66%?4.17%,24.74%?2.54% and 21.51%?6.70%,respectively.Compared to the NS control group(vessel area was 30.68%?(4.64%)),there was an obvious difference(P0.05 among the three different concentration groups).Conclusions:arsenic trioxide injection has a strong inhibitory effect on angiogenesis,which may be used in suppressing cancer angiogenesis.

Objective To investigate paclitaxel cross resistance and provide information for clinical therapy by establishing a paclitaxel resistant human lung adenocarcinoma cell line.Method A paclitaxel resistant human lung adenocarcinoma cell line named with SPC-A1/Taxol was developed by intermittent exposure to gradually increasing concentration of taxol.Resistant index was calculated from median inhibitory concentration(IC50)which was evaluated by MTT assay.Results SPC-A1/Taxol cell line displayed high resistance to taxotere,vinorelbine,vincristine and doxorubicin.It also displayed median or low resistance to camptothecins and podophyllotoxins.No cross resistance was observed to antitumor platinum and antimetabolite drugs and elemene emusion.Conclusion SPC-A1/Taxol cell line is a typical multidrug-resistant cell line in vitro.It could be useful for studing the cross resistance and direct clinical medication.

Objective To promote the development of oncologic nursing by establishing the accreditation standards for oncologic nursing professional training base.Methods In the early stage Delphi method was used to make a consultation with 21 experts for the construction of accreditation standards for oncologic nursing professional training base.Then the weights of each level was determined by using Analytic Hierarchy Process (AHP).Results Five first-level indicators were established,including oncologic nursing,clinical practice teaching staff,training management,the basic conditions of the department and the basic conditions of the hospital,their weights were 0.385 5,0.248 4,0.160 0,0.121 3 and 0.084 9.Conclusions The accreditation standards for oncologic nursing professional training base is constructed by AHP.It can make the accreditation standards more scientific and reliable to provide a quantitative basis for the review.

Objective To compare the effect of different body position and length of bed time after lumbar puncture on the postoperative headache.Methods Literatures were searched at home and abroad through the database,and provided comprehensive quantitative analysis to compare the effect of different body position and length of bed time after lumbar puncture on the postoperative headache by the Cochrane collaboration Meta-analysis.Results A total of 20 studies (3 514 patients) were included for Meta-analysis.Mter lumbar puncture for the low supine pillow and the pillow recumbent position,headache incidence rate had no significant difference between the two positions,combined odds ratio (OR) and 95％ confidence intervals were 0.87 (0.41-1.87)(P＞ 0.05);After lumbar puncture to stay in bed for a long time to rest (≥ 4 h) and short time in bed rest (＜1 h),headache incidence rate had no significant difference between the two different time,the combined odds ratio (OR) and 95％ confidence intervals were 0.77 (0.58-1.02)(P ＞ 0.05).Conclusions After lumbar puncture,the occurrence rate of headache is not increased after taking a low pillow lying position or a short time in bed rest (＜1 h).

Objective To investigate the effect of informationalized monitoring processing system in prevention and control of pressure ulcer. Methods The informationalized monitoring processing system was constructed to collect information. The nursing department sent it to the ulcer treatment group and they worked together to treat and control the ulcers in patients in a dynamic and real-time way. The effect was compared before and after application. Results After use of the system, the pressure ulcers incidence in the hospital was significantly decreased as compared with pre-construct of the system. The reporting and improvement rates were significantly improved than those before(P<0.05). Conclusion The use of the informationalized monitoring processing system makes the reporting of pressure ulcers timely and accurate, helping control the occurrence and treatment of ulcers dynamically, so that the quality of pressure ulcer prevention and control is improved.