1.Observation of patients with acute coronary synerome and contrast-induced nephropathy
Chinese Journal of Primary Medicine and Pharmacy 2008;15(11):1795-1796
Objective To analyse the incidence of CIN and the effect on renal function in 48 ACS patients.Methods 48 patients Ccr < 60ml/min have done percutaneous coronary intervention,according to measure anyday Scr,after operation seven days,to analyse the incidence of CIN and effect on renal function.Results 48 patients Ccr < 60ml/min undergoing percutaneous coronary intervention, six patients experienced CIN, incidence of CIN was 12.5% ,18 patients in Scr > 132.6mL/min,incidence of CIN 33.3%, two patients Ccr < 30mL/min experienced CIN.In patients who had renal dysfunction combining.with DM expeviously than in other patients, and Ccr after operation is lower than before operation.Conclusion CIN prones to oecur in ASC patients with renal dysfunction and is relative to Ccr and Scr closely.
2.Measurement of lumbar vertebral body by spiral CT and its clinical significance
China Medical Equipment 2016;13(4):61-63,64
Objective:To obtain the volume of thoracolumbar vertebral(T12-L5)in elderly people by CT post processing software, and establish the calculation formula of lumbar vertebral body volume from L1 to L4.Methods: Collect the elderly lumbar CT examination cases, 60 normal elderly people without lumbar lesions were included in this study. The volume of each vertebral body from T12 to L5 was obtained by processing software after a lumbar CT scan. The volume values of vertebral body from L1 to L4 were regarded as dependent variables and the volumes of upper and lower vertebral body was considered as independent variables. All the data were analyzed with multiple linear regression method.Results: There was a correlation between the volume of each lumbar vertebral from L1 to L4 and volumes of adjacent vertebral bodies, and the multivariate linear regression equation between them was obtained successfully.Conclusion: The volume of vertebral body can be accurately measured by CT processing software, and the calculation formula can be used to predict the normal vertebral volume value before fracture. The ratio of bone cement quantity to vertebral volume value can be earned and used to guide the operation of bone cement implantation for the further study.
3.Metabonomics: a Revolution in Progress
Progress in Biochemistry and Biophysics 2006;33(5):401-417
Metabonomics is the branch of science concerned with the quantitative understandings of the metabolite complement of integrated living systems and its dynamic responses to the changes of both endogenous factors (such as physiology and development)and exogenous factors (such as environmental factors and xenobiotics). As a holistic approach, metabonomics detects, quantifies and catalogues the time related metabolic processes of an integrated biological system, ultimately, relates such processes to the trajectories of the pathophysiological events. Ever since its birth in 1999, metabonomics has already been described in more than 800 scientific papers and half dozen patents, amongst which almost 700 papers were experimental articles. Now, metabonomics has been established as an extremely powerful analytical tool and hence found successful applications in many research areas including molecular pathology and physiology, drug efficacy and toxicity, gene modifications and functional genomics, and environmental sciences. This holistic approach has thus become an important part of systems biology and has now evolved to be a unique part in global systems biology. The essence of metabonomics and some of the present applications were reviewed to illustrate the rapid development of this extremely exciting new frontier.
4.The Effects of Zhigancao and Glycyrrhizic Acid on Transmural Potential of Reverted Mouse Small Intestine in Vitro
Chinese Traditional and Herbal Drugs 1994;0(12):-
Electrical potential difference (PD) was measured across the wall of reverted small intestinal saes of mice. The effect of glycyrrhizic acid on transmural potential related to Na+ and glucose transport were investigated. It was found that both zhigancao (100g/L ) and glycyrrhizic acid (2. 5mmol/L ) decreased the PD (P<0.01).According to the theory of active transport of glucose, we inferred that zhigancao and glycyrrhizic acid possibly produce an inhibitiory effect on Na+. K+-ATP ase,resulted in a blocking effect on sodium channel.
5.Study in application of nurse security scale in elderly inpatients for security precaution
Chinese Journal of Practical Nursing 2008;24(19):21-23
Objective To seek the best method for security precaution of elderly inpatients.Methods Elderly patients(296 cases) from January to August in 2006 and elderly patients(336 cases) from January to August in 2007 were divided into the control group and the improved group.The improved group received selective safety precaution measures after assessment of crisis degree by nurse security scale.The control group was given routine security nursing measures.The hospitalization time and incidence of unsafe events were compared in the two groups. Results The two groups were different in the following aspects:hospitalization time, incidence of unsafe events,satisfaction degree of family members,shift time of nurses,satisfaction degree of nurses. Conclusions To supply selective security nursing for elderly patients after assessment of crisis degree by nurse security scale at the admission day could decrease the incidence of un-safe events and hospitalization time.At the same time it shortened the shift time and increased shift efficien-cy to realize the win-win relations between nurses and patients.
6.Application of ultrasound-guided peripherally inserted central catheter insertion in elderly patients
Chinese Journal of Clinical Nutrition 2010;18(1):16-18
Objective To explore the feasibility and complications of ultrasound-guided peripherally inserted central catheter (PICC) insertion in elderly patients. Methods Ultrasound-guided PICC insertion was performed in 37 elderly patients with modified Seldinger's technique. Eighteen (48.6%) patients had invisible or impalpable shallow veins in elbow joints. The post-insertion success rate and complications were analyzed. Results The success rate was 100% among these 37 elderly patients. The indwelling patency duration was (32.0 ± 19.8)days. Two catheters in 2 (5.8%) patients were removed on the 21st and 39th day because of deep venous thrombosis. PICCs remained in place in 18 (48.6%) cases. Conclusions Ustrasound-guided PICC insertion is a safe procedure with high success rate. It can also be applied in patient whose shallow vein is not visible or palpable in elbow joint.
7.Application of 18F-fluorothymidine PET/CT in diagnosis of tumor
Chinese Journal of Interventional Imaging and Therapy 2009;6(4):388-391
18F fluorodeoxyglucose, as a kind of tracer, has its limitations in positron emission tomography/computed tomography (PET/CT). 18F-fluorothymidine (18F-FLT) is a kind of new tracer. The value of 18F-FLT in diagnosis of tumor, tumor staging and assessment of therapeutic effects was reviewed in this article.
8.Progress in medical ultrasound image restoration based on blind deconvolution
International Journal of Biomedical Engineering 2015;38(2):119-123
Medical ultrasound imaging suffers from poor resolution due to its inherit imaging mechanism.In order to obtain the important diagnostic image in detail,restoration procedure needs to be performed.However,in practical ultrasound imaging,it's difficult to demonstrate the degradation process in detail.Therefore,blind image deconvolution is applied to estimate the original image from the degraded image with unknown point spread function or little available prior knowledge.In this paper,the main algorithms of medical ultrasound image restoration based on blind deconvolution are reviewed and classified into two categories,priori or joint with the image,according to the identification methods,and the basic theories and improved methods are analyzed and discussed.Finally,the future directions in blind restoration for medical ultrasound images are proposed.
9.Separation of total coumarin in Artemisia capillaris by solvent sublation
Chinese Traditional and Herbal Drugs 1994;0(05):-
Objective An effective method for separating coumarin from Artemisia capillaris by solvent sublation was established.Methods The effects of sublation solvent,the concentration of sample solution,N2 gas flow rate,pH value of solution,sublation time,and electrolyte NaCl etc.on the sublation efficiency were investigated and the optimal conditions of the solvent sublation were obtained.Results In the optimal conditions,the results of the solvent sublation were evaluated and compared with the solvent extraction.Conclusion The experimental results show that this method is simple and rapid,and the efficiency of coumarin by solvent sublation is far better than that by the solvent extraction.
10.Research in hemodynamics and cardiac function evaluation of preterm infants
International Journal of Pediatrics 2014;(4):341-343,344
Cardiac dysfunction in preterm infants is a common acute and critical illness,associated with higher mortality,and can cause severe short-term and long-term sequelae. Therefore,understanding the main fea-ture of hemodynamics in premature neonates,and the accurate and appropriate clinical monitoring methods are essential to assess cardiac function in early time. This review summarizes the main hemodynamic problem and cardiac function assessment methods in preterm neonates.