Purpose: To detect the mRNA expression of epithelial skeleton protein CK19 in the peripheral blood of patients with colorectal cancer; to study its relationship to other clinicopathological parameters; and to discuss if the detection can help post-operative adjuvant therapy. Methods: A total of 39 blood samples from colorectal cancer patients were included in the study. Specific RT-PCR primers were used to avoid the amplification of pseudogenes. Results: Of 39 patients 31 showed CK19 mRNA expression (79.5%) . The patients in Dukes stage C and D showed higher frequency of CK19 mRNA expression than that in Dukes A and B (P

Objective:To explore the factors affecting the safety of home environment for device-aided elderly people, so as to provide a basis for improving the safety of the elderly's home environment and promoting aging-adapted reform.Methods:From August 2021 to March 2022, stratified cluster sampling was used to select 326 device-aided elderly people from 8 communities in Urumqi City as the research subject. The survey was conducted using the General Information Questionnaire, Capacity Assessment Standard Table for the Elderly, Home Environment Safety Assessment Scale for the Elderly, and Home Environment Ageing-adapted Reform Cognition and Needs Concise Questionnaire for the Elderly. Multiple linear regression was used to explore the influencing factors of home environment safety for device-aided elderly people.Results:A total of 326 questionnaires were distributed, and 305 valid questionnaires were collected, with an effective recovery rate of 93.56% (305/326) . The influencing factors of home environment safety for device-aided elderly people included housing area, self-evaluation of the home environment, chronic diseases, monthly pension income, and cognition of aging-adapted reform ( P<0.05) . Conclusions:The aging-adapted reform of home environment should focus on elderly people who suffer from chronic diseases, have poor self-evaluation of the environment, have low monthly pension income and cognition of aging-adapted reform. Relevant departments should promote the self-evaluation methods of home environment and knowledge on home aging-adapted reform.