1.Clinical analysis of 50 cases with pulmonary inflammatory pseudotumor
Chinese Journal of Primary Medicine and Pharmacy 2009;16(11):1936-1937
Objective To explore the clinical diagnosis and surgical treatment of inflammatory pseudotumor of the lung. Methods From January 2002 to December 2008,the clinical data of 50 cases with pulmonary inflammatory pseudotumor were retospectively analyzed. Result 18 cases of preoperative diagnosis, the four cases of lobectomy, pulmonary wedge resection in 13 cases, and the rest are mass surgery, intraoperative tumor mostly see substantive, tumor visceral pleural surface without sag and shrinkage, tumor palpation There are hard and soft white felt, with incomplete tumor capsule, easily stripped. Resection of the pathological specimens were confirmed to be inflammatory pseudotumor, no operative complications and death in patients with follow-up 1~8 years, both curvived, without recurrence. Conclusion Inflammatory pseudotumor of their clinical performance and imaging characteristics of the lack of change in the low rate of preoperative diagnosis, surgical treatment of the main diagnostic, intraoperative frozen biopsy to determine pathology surgery, surgical approach to the limitations of pneumonectomy or lobectomy excision.
2.Progress in diagnosis and treatment of acute graft versus host disease
Journal of Leukemia & Lymphoma 2014;23(4):244-247
Graft versus host disease is the most common complication of allogeneic hematopoietic stem cell transplantation.It includes two different types,i.e.acute and chronic types.Acute graft versus host disease (aGVHD) is the immune response of T cells from the donor to unmatched major histocompatibility complex (MHC) from the host.It has unique pathogenesis and pathological changes and complex clinical manifestations with multiple organs involved.This paper reviewed the progress from home and abroad in diagnosis and treatment of acute graft versus host disease.
3.Studies on the changes of fibronectin content in rabbits of hemorrhagic and endotoxic shock
Chinese Journal of Pathophysiology 1986;0(03):-
The changes of plasma Fn content in rabbits of hemorrhagic and endotoxic shock has been assayed by means of single and double immunodiffusion tests. The results showed that Fn level significantly declined at 30 minutes after hemorrhagic shock and remained at low level with development of shock. But in the rabbitns transfused at 30 minutes after shock Fn level turned to normal as blood pressure increased. Fn content was significantly elevated at 30 minutes and significantly decreased at 60 minutes after endotoxic shock. The possible pathophysiologic and clinical significance of these changes was disscussed.
4.Clinical Analysis on 30 Cases of Histiocytosis
Journal of Kunming Medical University 1988;0(03):-
The pathogenesis and clinical manifestation of histiocytosis are veriant, and misdiagnosis is relatively high. We reviewed a total of cases of this disease and related literature, and the possibility pathogenesis and its clinical features. were discussed.
5.Translation of the English Learning Anxiety Scale and Test of its Reliability and Validity
Chinese Mental Health Journal 1992;0(01):-
Objective: To make an English Learning Anxiety Scale (ELAS) based on the Foreign Language Classroom Anxiety Scale (FLCAS) and to do a psychometric test of the ELAS. Method: After translation of the FLCAS into Chinese and did item adaptation to form an ELAS. It was administered to 669 college students with major field other than English. Result: The ELAS was composed of 23 items in four subscales: nervousness , worry, apprehension of being questioned, and sense of anxiety.Factor loadings in the exploratory factor analysis were: A1, 0.46-0.70; A2, 0.53-0.73; A3, 0.55-0.70, A4,0.50-0.67. 48.95% of the total variance could explained. The Cronnbach?is 0.70-0.89, split-half reliability(S-B), 0.71-0.88. ?2/df, RMSEA, GFI, AGFI, NFI, NNFI, CFI, IFI of the goodness of fit indices of confirmatory factor analysis were 2.40, 0.05, 0.92, 0.90, 0.85, 0.89, 0.90, 0.90. The correlation coefficient between ELAS and CET4 score is-0.25~0.64. The correlation coefficient between ELAS and the subscales was 0.69~0.80. The correlation coefficient between the subscales was 0.45~0.63. Conclusion: ELAS has good reliability and validity, could be an effective research instrument in studying anxiety of Chinese college students with major field other than English.
6.Study on the floating characteristics of the calcium alginate-chi-tosan intragastric floating beads
Chinese Journal of Marine Drugs 2000;0(06):-
Objective To prepare calcium alginate-chitosan intragastric floating beads and investigate the influences of various factors on the floating characteristics of beads.Methods Sodium alginate solution added with frother was slowly dripped into chitosan-calcium chloride solution added with acetic acid,calcium alginate-ehitosan intragastric floating beads were obtained after drying.The effects of frother,addition amount of acetic acid,the concentration of alginate solution,chitosan and calcium chloride solution on the floating characteristics of beads were investigated.Results Frother and addition amount of acetic acid were the main influence factors on the floating characteristics,and the concentrations of alginate solution, chitosan and calcium chloride solution also had some influences.Conclusion The calcium alginate-chitosan intragastrie floating beads with favorable floatability could be achieved through adjusting the formula,it laid a foundation for the furether development of the preparations in intragastric floating preparations.
7.OBSERVATION ON CHROMOSOME FRAGILE SITES AND MICRONUCLEUS OF PATIENTS WITH LUNG CANCER UTERUS CANCER OR OVARY CANCER
Journal of Chongqing Medical University 1987;0(01):-
The ghrompspine fr.agile .sites and micronucleus expression of peripheral lymphocytes were studied in 23 cases with lung cancer 23 cases with uterus cancer 13 cases with ovary cancer and 20 control subjects, using TC199 medium containing 5% bovine serum. The results showed that the chromosome aberration and micronucleus rates of the three group patients were significantly higher than that of the control group, but differences between the three group patients were not statistically significant
8.Expression of interleukin-6 and matrix metalloproteinase-3 in the synovial fluid of osteoarthritis patients
Chinese Journal of Tissue Engineering Research 2015;(33):5259-5263
BACKGROUND:It is confirmed that the onset of osteoarthritis is closely related to inflammatory cytokines. OBJECTIVE: To investigate the levels of interleukin-6 and matrix metaloproteinase-3 in the synovial fluid of patients with osteoarthritis and their correlation with the severity of osteoarthritis. METHODS: Synovial fluid specimens of 78 patients were harvested to detect the levels of interleukin-6 and matrix metaloproteinase-3 using ELISA assay. The severity of osteoarthritis was estimated by the Hospital for Special Surgery (HSS) score. Pearson correlation analysis was adopted to explore the pairwise correlations between interleukin-6, matrix metaloproteinase-3 and HSS score. RESULTS AND CONCLUSION:The levels of interleukin-6 and matrix metaloproteinase-3 in the synovial fluid were (13.1±5.7) and (989.3±429.5) μg/L, respectively; the HSS score was (56.4±12.0) points. Pearson correlation analysis showed that the expression levels of interleukin-6 and matrix metaloproteinase-3 had a significant positive correlation (r=0.70,P< 0.001); the levels of interleukin-6 and matrix metaloproteinase-3 had a negative correlation with the HSS scores (r=-0.70,r=-0.75,P < 0.001). Experimental findings show that there is a positive correlation between interleukin-6 and matrix metaloproteinase-3 in the synovial fluids, and these two cytokines also have a positive correlation with the severity of osteoarthritis, indicating that to measure interleukin-6 and matrix metaloproteinase-3 levels in the synovial fluids of osteoarthritis patients is important for early diagnosis and treatment of osteoarthritis.
9.Training Status of Clinical Pharmacist of Chinese Medicine and Suggestions for Training Mode
China Pharmacist 2015;(6):961-963,991
In the paper, the training situation of clinical pharmacist of Chinese medicine was analyzed through the current work situation of clinical pharmacy of Chinese medicine in China. The lack of staff and low level are the undoubted facts. In order to promote clinical pharmacy of traditional Chinese medicine, clinical pharmacists with high quality should be trained. How to train clinical phar-macists of Chinese medicine with high quality, some suggestions were put forward from two aspects of the college education reform and clinical training:①The existing education system should be reformed to establish reasonable higher education for clinical pharmacy of Chinese medicines, including the reform of education system, the curriculum adjustment, practice direction change and so on;②With the attention of all the parties, practical talents of clinical pharmacy of Chinese medicine should be trained in clinics, including the na-tion should start the training for clinical pharmacist of Chinese medicine, hospitals should train practical clinical pharmacist of Chinese medicine and carry out the corresponding work of clinical pharmacy of Chinese medicine, staff should improve self quality and so on.
10.Clinical Significance in Anatomy of Mesoretal Tail During Radical Operation for Rectal Cancer
Pan CHI ; Huiming LIN ;
Chinese Journal of Bases and Clinics in General Surgery 2003;0(02):-
Objective To investigate the anatomical mark of attachment edge in mesorectal tail and the effect of its morphologic distribution in performing total mesorectal excision (TME). Methods The gross specimens of 220 consecutive patients with the middle lower rectal cancer were collected by a group of surgeons.Patients were divided into two groups.①Group in saving sphincter. Ⅰa group, low anterior resection (LAR): 81 patients with lesions between 5 and 6 cm from the anal verge underwent LAR ; Ⅰb group, anterior resection (AR): 68 patients with lesions between 7 and 8 cm from the anal verge underwent AR.②Group in resecting sphincter. Abdominoperineal resection (APR): 71 patients with lesions between anal verge and 5 cm from the anal verge underwent APR. Results ①The circular edge of mesorectal tail is attached on rectal wall of 1 cm above anal hiatus of levators,which level parallels the lower margin of lower rectal cancer.In order to reset distal rectal wall of 2 and 3 cm,undergoing LAR must avoid injuring rectal wall when dissecting muscular vessel of rectum continue along the levators fascia to the anal hiatus.②The attachment morphology of mesorectal tail is a circular flake and not circular linear in shape. There are a little of fat tissue between posterior rectal wall and mesorectal tail,the length of its longitudinal attachment is (1.269?0.171) cm (81 cases in LAR group and 71 cases in APR gourp).Because the distal resective margin of rectum undergoing AR just locate in area of flake attachment of mesorectum, removing mesorectum around rectal wall must avoid injuring the rectal wall. Conclusion The mesorectal tail is a circular flake and attaches on rectal wall of 1.0 cm above anal hiatus of levatorani.Undergoing LAR or AR must avoid to injure rectal wall,which may result in leakage of anastomosis when removing mesorectal tissuce around distal rectal wall.