1.Effects of Small Dose of Bupivacaine Lumbar-Epidural Block on Related Indexes in Women Underwent Ce-sarean Section
Tian HAN ; Qiuming XIE ; Huijiang GUO ; Huixian CHU
China Pharmacy 2017;28(9):1200-1203
OBJECTIVE:To investigate the effects of small dose of bupivacaine lumbar-epidural block on related indexes inwomen underwent cesarean section. METHODS:124 singleton term primipara underwent elective cesarean section were randomly divided into observation group(62 cases)and control group(62 cases). Observation group received 0.5% bupivacaine 7.5 mg lum-bar anesthesia+1.6% lidocaine epidural block. Control group received 0.5% bupivacaine 10 mg lumbar anesthesia+1.6% lidocaine epidural block. HR,SBP,DBP,onset time of sensory block,fixation time of block level,operation start time,the occurrence of traction reaction and supine hypotensive syndrome,the application of ephedrine,Apgar score the occurrence of ADR were ob-served in 2 groups before anesthesia(T0),1(T1),3(T2),5 min(T3)after anesthesia,at skin incision(T4),after fetal disengage-ment(T5). RESULTS:There was no statistical significance in HR,SBP and DBP between 2 groups at T0(P>0.05). There was no statistical significance in HR,SBP and DBP of observation group at different time points(P>0.05). At T1-3,SBP and DBP of con-trol group were significantly lower than at T0 and observation group;HR was significantly higher than at T0 and observation group, with statistical significance(P<0.05);there was no statistical significance in HR,SBP and DBP of control group,compared to at T1-3(P>0.05);there was no statistical significance in above 3 indexes of control group at T4-5,compared to at To and observation group(P>0.05). The onset time of sensory block,fixation time of block level and operation start time in observation group were all longer than control group;the incidence of supine hypotensive syndrome,the number of ephedrine cases,the amount of ephed-rine,the incidence of nausea and vomiting,the incidence of postoperative urinary retention were significantly lower than control group;the incidence of traction reaction was significantly higher than control group,with statistical significance(P<0.05). There was no statistical significance in the incidence of respiratory depression,Apgar score,overall incidence of ADR between 2 groups (P>0.05). CONCLUSIONS:The small dose of bupivacaine lumbar-epidural block for women underwent cesarean section keep he-modynamics stable and reduce the incidence of supine hypotensive syndrome without increasing the incidence of ADR.
2.Study on Pulse Recordings of College Students with Different Emotional States
Huijiang SHAO ; Wei YANG ; Weirong PAN ; Rui GUO ; Yiqin WANG ; Haixia YAN
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(7):1214-1218
This paper was aimed to investigate the changes of pulses under different emotional states.Based on the emotional pulse theory of traditional Chinese medicine (TCM),with college students as the research object,through films to stimulate different emotional expressions (i.e.,calm,sad and happy) of college students,the pulse recordings of college students were acquired in this study.The time domain parameters of pulses of college students under three types of emotional states were extracted.The difference among three groups of time-domain parameters was calculated by nonparametric test.Based on the time-domain parameters,the Support Vector Machine (SVM) classifier was used to classify three types of emotional states.The results showed that there were significant differences in three groups of time domain parameters (h3/h1,t and As/(As+Ad)).And the average recognition rate of three types of emotion states was 74.25% based on the time-domain parameters of the pulse recordings.It was concluded that the pulse parameters can provide objective reference for emotional changes.It can be used to identify emotional states.
3. Comparison of short-term and long-term outcomes between thoracoscopic pneumonectomy and open pneumonectomy for non-small cell lung cancer: a study based on propensity score matching
Xiaokang GUO ; Huijiang GAO ; Maolong WANG ; Bin HAN ; Bin WANG ; Nan GE ; Guodong SHI ; Yucheng WEI
Chinese Journal of Surgery 2020;58(2):131-136
Objective:
To compare the short-term and long-term results of thoracoscopic and open pneumonectomy for non-small cell lung cancer.
Methods:
The clinical data of patients with non-small cell lung cancer who underwent pneumonectomy in the Department of Thoracic Surgery, Qingdao University Hospital from January 2008 to December 2016 were collected. Totally 142 patients (55 in the thoracoscopic group and 87 in the open group) were included in the study. A total of 29 pairs of patients were successfully matched by propensity score matching (PSM). Perioperative outcomes and overall survival were compared between the two groups using