1.The relation between vascular endothelial growth factor receptor 3 and bladder cancer lymphatic metastasis
Zhentao YANG ; Huien LIU ; Wanfeng ZHANG ; Hongjie WANG ; Xiaohui DING ; Ming LI ; Baifeng WANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(5):678-680
Objective To explore vascular endothelial growth factor-C (VEGF-C),vascular endothelial growth factor receptor 3 (VEGFR-3) in the bladder cancer tissue of the expression and the relationship with the tumor lymph node metastases of bladder cancer tissue,Methods The VEGF-C,VEGFR-3 expression was detected by Elivision TM plus two footwork.Results In 18 cases of bladder cancer organization,VEGF-C expression positive rate was 72%,VEGFR-3 express positive rate was 67%.VEGF-C in the bladder cancer of the transfer of the expression level compared to the lymph nodes of the transfer of the lymph node has not occurred to high.Conclusion In the bladder cancer organization and the surroundinglymph nodes,VEGF-C,VEGFR-3 expression level and lymph node metastasis is closely related.VEGF-C,VEGFR-3 expression intensity can be used as a lymph node metastasis in bladder cancer index.
2.Photoselective vaporization of prostate for the treatment of very elderly patients with benign prostatic hyperplasia
Wanfeng ZHANG ; Hongjie WANG ; Guiping WANG ; Jialin QU ; Xiaohui DING ; Huien LIU
Chinese Journal of General Practitioners 2009;08(6):412-413
A total of 156 elderly patients (aged ≥ 70 years) with symptomatic bladder outlet obstruction as a result of benign prostatic hyperplasia (BPH) underwent trmsurethral photoselective vaporization (PVP). Pre- or post-operative urine flow rate, residual urine volume level, International Prostate Symptom Score (IPSS), and quality of life (QOL) score were recorded. Our data showed that maximum urine flow rate and residual urine volume were improved at 1, 12, 24, and 36 months following the treatment. There was statistically significant difference in IPSS and QOL when the intervention was considered (P < 0. 05). PVP might be a treatment of choice for high-risk elderly patients with obstructive BPH.