1.Clinical Observation on External Application and Enema of Herbal Medicine Combined with Acupuncture for Adhesive Intestinal Obstruction
Huidong LI ; Yangchun HONG ; Mei HUANG
Journal of Guangzhou University of Traditional Chinese Medicine 2000;0(04):-
0.05).Pain-disappearing time,anus-bubbling time,and time for gas-fluid plane disappearing were shortened in group C,and drainage volume from nutrient canal during gastrointestinal decompression obviously reduced on the second day as compared with those in groups A and B(P
2.Effect of Xiongshang RecipeⅠon Tumor Necrosis Factor and Interleukin-8 in Patients with Acute Pulmonary Contusion
Huidong LI ; Yangchun HONG ; Mei HUANG
Journal of Guangzhou University of Traditional Chinese Medicine 2000;0(04):-
Objective To investigate the effect of Xiongshang RecipeⅠ(XPI)on serum inflammatory cytokines of tumor necrosis factor (TNF)and interleukin-8(IL-8)in acute pulmonary contusion patients.Methods Thirty acute pulmonary contusion patients were equally randomized into the control group (receiving routine western medical treatment)and the treatment group (received routine western medical treatment and oral use of XPI).The treatment lasted 2 weeks.Thirty healthy physical examinees served as the contemporaneous normal controls.Secondary pulmonary contusion,recovery time and the serum levels of TNF and IL-8 were observed after pulmonary contusion.Results Serum levels of TNF and IL-8 in the treatment group after treatment were decreased(P
3.Clinical study of pelvic autonomic nerve preservation in curative excision of male patients with rectal cancer
Bin CHEN ; Kuisheng LIN ; Jinqu CHEN ; Bin PU ; Huidong HONG
Clinical Medicine of China 2011;27(12):1316-1318
Objective To evaluate the effects of pelvic autonomic nerve preservation (PANP) during the radical resection of rectal carcinoma on the sexual and urinary function of male patients.Methods The sexual and urinary dysfunction rates from 45 male patients who undergone PANP and 45 control patients who did not undergo PANP during radical resection of rectal carcinoma were analyzed.Results In the PANP group,the incidences of erectile dysfunction,ejaculatory dysfunction and urinary dysfunction were 26.67%,24.44% and 28.89%,respectively.But in control group,the above three rates were 57.78%,60.00% and 62.22% in order.The rates of these three dysfunctions significantly were different between the two groups ( x2 =8.92,11.66,10.08,P < 0.01 ).Conclusion PANP during radical resection of rectal carcinoma could reduce the post-operative sexual dysfunction and urinary dysfunction.
4.Protective effects of splenectomy of small-for-size syndrome in rat models
Gang WU ; Huidong SUN ; Lei YANG ; Hong LI ; Ying CHENG ; Yongfeng LIU
Chinese Journal of Organ Transplantation 2010;31(6):365-368
Objective To explore the role of splenectomy in the prevention and treatment of small-for-size liver in rat models, as well as its pathophysiologic mechanism in the development of a small-for-size syndrome (SFSS). Methods The models of sham-operation and 80 % partial hepatectomy (PH) were used in rats. In the experiment group splenectomy was performed following 80% PH. The concentrations of serum tumor necrosis factor (TNF-α), the content of NF-cB p65 in liver nuclear extracts, the expression of TNF-α, intercellular adhesion molecular (ICAM-1), and proliferating cell nuclear antigen (PCNA) transcripts, the activities of serum aspartate transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH), total bilirubin (TB), albumin (Alb) cholinesterase (CHE), and liver myeloperoxidase (MPO) were analyzed. Portal venous pressures (PVP),incidence of SFSS,and one-wk survival rate were measured. Results In the control rats,The PVP was obviously elevated immediately after PH. The level of NF-κB p65 was obviously increased at the first h and peaked at about 3rd h postoperatively. The transcription of TNF-α and ICAM-1 and the release of serum TNF-α were significantly increased 3 h after PH. Capillary endothelial cells of the livers strongly expressed ICAM-1 24 h after PH. Splenectomy significantly reduced the PVP and the content of NF-κB p65 in the livers in concurrence with the expression of TNF-α and ICAM-1 gene as well as the activity of MPO at the corresponding time points after PH (P<0. 05), while increased the expression of PCNA gene (P<0. 05). Administration of splenectomy resulted in a statistically significant decrease in AST, ALT, LDH, TB, the incidence of SFSS and increase in one-wk survival rate (P < 0.05 ). Conclusion Splenectomy alleviates liver injury and promotes liver regeneration in small-for-size liver rats by reducing portal vein perfusion and pressure,and suppressing NFκB activation and subsequent expression of proinflammatory mediators.